5 results match your criteria: "162698The First Affiliated Hospital of Jinan University[Affiliation]"
Analysis of Prognostic Factors of Low-Grade Gliomas in Adults Using Time-Dependent Competing Risk Models: A Population Study Based on the Surveillance, Epidemiology, and End Results Database.
Cancer Control
December 2022
Department of Neurology and Stroke Center, Ringgold: 162698The First Affiliated Hospital of Jinan University, Guangzhou, China.
Background: Because of multiple competing death outcomes and time-varying coefficients, using a Cox regression model to analyze the prognostic factors of low-grade gliomas (LGG) may lead to a possible bias. Therefore, we adopted time-dependent competing risk models to obtain accurate prognostic factors for LGG.
Methods: In this retrospective cohort study, data were extracted from patients enrolled in the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2018.
The Incidence Trend of Papillary Thyroid Carcinoma in the United States During 2003-2017.
Cancer Control
October 2022
Department of Clinical Research, 162698The First Affiliated Hospital of Jinan University, Guangzhou, China.
Article Synopsis
- The incidence of papillary thyroid carcinoma (PTC) increased significantly from 2003 to 2017, but the growth rate began to slow down after 2009 and showed a decline starting from 2015.
- Various demographic factors, such as sex, age, race, and tumor characteristics, reflected similar downward trends in PTC incidence, suggesting a comprehensive change in detection and diagnosis.
- The study emphasizes the importance of addressing overdiagnosis in reducing PTC prevalence, recommending further research to confirm these trends with more recent data.
Identification and analysis of the predictive urinary exosomal miR-195-5p in lupus nephritis based on renal miRNA-mRNA co-expression network.
Lupus
December 2022
Key Laboratory of Drug Metabolism Research and Evaluation of National Medical Products Administration, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, 70570Southern Medical University, Guangzhou, China.
Objective: Lupus nephritis (LN) is the main complication of systemic lupus erythematosus (SLE), causing huge financial burden and poor quality of life. Due to the low compliance of renal biopsy, we aim to find a non-invasive biomarker of LN to optimize its predictive, preventive, and personalized medical service or management.
Method: Herein, we provided a bioinformatic screen combined clinical validation strategy for rapidly mining exosomal miRNAs for LN diagnosis and management.
A monoclonal antibody against basic fibroblast growth factor attenuates cisplatin resistance in lung cancer by suppressing the epithelial-mesenchymal transition.
Int J Immunopathol Pharmacol
June 2022
Department of Traditional Chinese Medicine, 144991Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
: To investigate the underlying mechanisms of how the basic fibroblast growth factor monoclonal antibody (bFGFmAb) attenuates cisplatin (DDP) resistance in lung cancer using A549 cells and cisplatin-resistant A549 cells (A549/DDP). : Cancer cell proliferation, cell viability, and 50% inhibitory concentration (IC50) of cisplatin were assessed. Transwell assays were utilized to evaluate the invasion activity of tumor cells in response to treatment.
View Article and Find Full Text PDFEpidemiology, Management, and Long-Term Survival Outcomes of Intracranial Typical Site Germinomas: An Analysis of the Surveillance, Epidemiology, and End-Results (SEER) Database.
Cancer Control
April 2022
Department of Clinical Research, 162698The First Affiliated Hospital of Jinan University, Guangzhou, China.
Background: The correlations of epidemiological characteristics and clinical outcomes with different tumor sites in patients with intracranial typical site germinomas (ICTSGs) have not yet been well established. We analyzed ICTSGs using a multicenter database, focusing on its demographic, management patterns, and long-term survival outcomes.
Methods: Patients diagnosed with ICTSGs were selected from the Surveillance, Epidemiology, and End-Results (SEER) database.