67 results match your criteria: "155 College St. Room 500[Affiliation]"

Deep learning model meets community-based surveillance of acute flaccid paralysis.

Infect Dis Model

March 2025

Artificial Intelligence & Mathematical Modeling Lab (AIMM Lab), Dalla Lana School of Public Health, University of Toronto, 155 College St Room 500, Toronto, ON, M5T 3M7, Canada.

Acute flaccid paralysis (AFP) case surveillance is pivotal for the early detection of potential poliovirus, particularly in endemic countries such as Ethiopia. The community-based surveillance system implemented in Ethiopia has significantly improved AFP surveillance. However, challenges like delayed detection and disorganized communication persist.

View Article and Find Full Text PDF

Background: Equitable access to vaccination remains a concern, particularly among population groups made structurally vulnerable. These population groups reflect the diversity of communities that are confronted with structural barriers caused by systemic racism and oppression and result in them experiencing suffer disadvantage and discrimination based on citizenship, race, ethnicity, ancestry, religion, spiritual beliefs, and/or gender identity. In Canada, Ontario public health units (PHUs) engage with faith-based organizations (FBOs) to improve vaccine confidence among populations made structurally vulnerable.

View Article and Find Full Text PDF

Improving social and emotional well-being (SEWB) among Indigenous adolescents is crucial. Since neurodevelopmental disorders (NDDs) are common in Indigenous people and adverse childhood experiences (ACEs) are important contributors to negative health outcomes throughout the lifespan, we investigated whether limited ACE exposure is associated with reduced risk of NDDs in Australian Indigenous teens using the data from multiple waves (Wave 1 to Wave 9, and Wave 11) of the Longitudinal Study of Indigenous Children (LSIC). We also examined the role of other protective factors, such as Indigenous cultural identity and school connectedness, against NDDs.

View Article and Find Full Text PDF

N-acetyl-aspartate (NAA) and myo-inositol (mI) are neurometabolites reflecting neuronal viability and astrocyte activity, respectively. These are quantified using proton magnetic resonance spectroscopy (1H-MRS) and may be biomarkers for Alzheimer's disease dementia (AD). Our objectives were: 1) Compare dorsolateral prefrontal cortex (DLPFC) NAA and mI levels between AD and cognitively healthy control participants (HC) 2) assess if NAA/mI ratio can distinguish groups, and 3) explore the relationship between metabolites and cognition.

View Article and Find Full Text PDF
Article Synopsis
  • * Using data from the Longitudinal Study of Indigenous Children (LSIC), researchers analyzed mother-child pairs to assess the correlation between healthy pregnancy practices and child development outcomes over a ten-year period.
  • * Results indicated that a significant majority of mothers maintained healthy pregnancies, and a high percentage of children had appropriate birthweights and showed no developmental delays, suggesting a positive association between maternal health and child development.
View Article and Find Full Text PDF

Dietary changes among people practicing Meatless Monday: A cross-sectional study.

Appetite

January 2025

Johns Hopkins Center for a Livable Future, Johns Hopkins University, 111 Market Place Suite 840, Baltimore, MD, 21202, USA.

Background: High meat consumption negatively impacts human and planetary health. Meatless Monday (MM) is a widely known public health initiative that promotes healthy and sustainable diets by encouraging people to eliminate meat for one day each week.

Objectives: This study investigated whether exposure to MM, through practicing MM and receiving the MM e-newsletter, is associated with reduced meat intake on days other than Mondays.

View Article and Find Full Text PDF

Trans subjectivities continue to be included in major compendia of mental illness, despite recent moves to depathologize "cross-gender identification." Regardless, the inclusion of "gender dysphoria" is often framed as a formal mechanism to support access to gender affirming care as transgender subjectivities are re-conceptualized as part of sex/gender diversity and away from madness. The latter permits trans individuals to evade sanist oppressions.

View Article and Find Full Text PDF

A longitudinal study on impact of emergency cash transfer payments during the COVID pandemic on coping among Australian young adults.

Sci Rep

August 2024

Faculty of Medicine and Health, School of Public Health, The University of Sydney, Edward Ford Building, A27 Fisher Rd, Sydney, NSW, 2006, Australia.

The coronavirus (COVID-19) pandemic has caused financial hardship and psychological distress among young Australians. This study investigates whether the Australian Government's emergency cash transfer payments-specifically welfare expansion for those unemployed prior to the pandemic (known in Australia as the Coronavirus Supplement) and JobKeeper (cash support for those with reduced or stopped employment due to the pandemic)-were associated with individual's level of coping during the coronavirus pandemic among those with and without mental disorders (including anxiety, depression, ADHD and autism). The sample included 902 young adults who participated in all of the last three waves (8, 9C1, 9C2) of the Longitudinal Study of Australian Children (LSAC), a nationally representative cohort study.

View Article and Find Full Text PDF

Decolonizing global AI governance: assessment of the state of decolonized AI governance in Sub-Saharan Africa.

R Soc Open Sci

August 2024

Artificial Intelligence & Mathematical Modeling Lab (AIMM Lab), Dalla Lana School of Public Health, University of Toronto, 155 College St Room 500, Toronto, ON M5T 3M7.

Global artificial intelligence (AI) governance must prioritize equity, embrace a decolonial mindset, and provide the Global South countries the authority to spearhead solution creation. Decolonization is crucial for dismantling Western-centric cognitive frameworks and mitigating biases. Integrating a decolonial approach to AI governance involves recognizing persistent colonial repercussions, leading to biases in AI solutions and disparities in AI access based on gender, race, geography, income and societal factors.

View Article and Find Full Text PDF

Factors associated with satisfaction of the australian rural resident medical officer cadetship program: results from a cross-sectional study.

BMC Med Educ

July 2024

Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Edward Ford Building, A27 Fisher Road, Camperdown Sydney, NSW, 2006, Australia.

Background: Australian Rural Resident Medical Officer Cadetships are awarded to medical students interested in a rural medical career. The Rural Residential Medical Officer Cadetship Program (Cadetship Program) is administered by the Rural Doctors Network on behalf of the NSW Ministry of Health. This study aimed to assess the overall experience of medical students and key factors that contributed to their satisfaction with the Cadetship Program.

View Article and Find Full Text PDF

Assessment of bidirectional impact of stigmatization induced self-medication on COVID-19 and malaria transmissions using mathematical modeling: Nigeria as a case study.

Math Biosci

October 2024

Africa-Canada Artificial Intelligence and Data Innovation Consortium (ACADIC), York University, Canada; Artificial Intelligence & Mathematical Modeling Lab (AIMM Lab), Dalla Lana School of Public Health, University of Toronto, 155 College St Room 500, Toronto, ON M5T 3M7, Canada; Department of Mathematics, University of Toronto, Bahen Centre for Information Technology, Room 6291, 40 St. George Street, Toronto, Ontario, Canada; Global South Artificial Intelligence for Pandemic and Epidemic Preparedness and Response Network (AI4PEP), Canada. Electronic address:

The continual social and economic impact of infectious diseases on nations has maintained sustained attention on their control and treatment, of which self-medication has been one of the means employed by some individuals. Self-medication complicates the attempt of their control and treatment as it conflicts with some of the measures implemented by health authorities. Added to these complications is the stigmatization of individuals with some diseases in some jurisdictions.

View Article and Find Full Text PDF

Understanding the impact of HIV on mpox transmission in the MSM population: A mathematical modeling study.

Infect Dis Model

December 2024

Laboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, Ontario, Canada.

The recent mpox outbreak (in 2022-2023) has different clinical and epidemiological features compared with previous outbreaks of the disease. During this outbreak, sexual contact was believed to be the primary transmission route of the disease. In addition, the community of men having sex with men (MSM) was disproportionately affected by the outbreak.

View Article and Find Full Text PDF

Surveillance bias occurs when variations in cancer incidence are the result of changes in screening or diagnostic practices rather than increases in the true occurrence of cancer. This bias is linked to the issue of overdiagnosis and can be apprehended by looking at epidemiological signatures of cancer. We explain the concept of epidemiological signatures using the examples of melanoma and of lung and prostate cancer.

View Article and Find Full Text PDF

Associations between noticing public health education campaigns about cannabis and risk perceptions in the northern Canadian territories: a cross-sectional study.

Health Educ Res

December 2024

Health Promotion, Chronic Disease and Injury Prevention, Public Heath Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1, Canada.

This study investigated whether noticing cannabis education campaigns was associated with increased cannabis risk perceptions in Canada's three territories following non-medical cannabis legalization. Data were from the Cannabis Policy Study in the Territories, including 2452 participants, age ≥16 years residing in Yukon, Northwest Territories and Nunavut. Poisson regression with robust standard errors were used to estimate associations between noticing cannabis education campaigns and moderate to very high risk perceptions of daily cannabis smoking, vaping, edible use and exposure to second-hand cannabis smoke, adjusting for sociodemographic characteristics and cannabis-use frequency.

View Article and Find Full Text PDF

Objective: Estimate the impact of 20 % flat-rate and tiered sugary drink tax structures on the consumption of sugary drinks, sugar-sweetened beverages and 100 % juice by age, sex and socio-economic position.

Design: We modelled the impact of price changes - for each tax structure - on the demand for sugary drinks by applying own- and cross-price elasticities to self-report sugary drink consumption measured using single-day 24-h dietary recalls from the cross-sectional, nationally representative 2015 Canadian Community Health Survey-Nutrition. For both 20 % flat-rate and tiered sugary drink tax scenarios, we used linear regression to estimate differences in mean energy intake and proportion of energy intake from sugary drinks by age, sex, education, food security and income.

View Article and Find Full Text PDF

Background: Health care routinely fails Indigenous peoples and anti-Indigenous racism is common in clinical encounters. Clinical training programs aimed to enhance Indigenous cultural safety (ICS) rely on learner reported impact assessment even though clinician self-assessment is poorly correlated with observational or patient outcome reporting. We aimed to compare the clinical impacts of intensive and brief ICS training to control, and to assess the feasibility of ICS training evaluation tools, including unannounced Indigenous standardized patient (UISP) visits.

View Article and Find Full Text PDF

Delivering health promotion during school closures in public health emergencies: building consensus among Canadian experts.

Health Promot Int

December 2023

MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria St, Toronto, ON M5B 1T8, Canada.

School-based health promotion is drastically disrupted by school closures during public health emergencies or natural disasters. Climate change will likely accelerate the frequency of these events and hence school closures. We identified innovative health promotion practices delivered during COVID-19 school closures and sought consensus among education experts on their future utility.

View Article and Find Full Text PDF

Genetic endowments for social capital: An investigation accounting for genetic nurturing effects.

Econ Hum Biol

January 2024

Institute of Health Policy, Management and Evaluation (IHPME), University of Toronto,  155 College St 4th Floor, Toronto, ON M5T 3M6, Canada; Canadian Centre for Health Economics,  155 College St 4th Floor, Toronto, ON M5T 3M6, Canada.

Despite social capital having been shown to be important for health and well-being, relatively little research has examined genetic determinants. Genetic endowments for education have been shown to influence human, financial, and health capital, but few studies have examined social capital, and those conducted have yet to account for genetic nurturing. We used the Add-Health data to study the effect of genetic endowments on individual social capital using the education polygenic score (PGS).

View Article and Find Full Text PDF

Minimal important difference of the 12-item World Health Organization Disability Assessment Schedule (WHODAS) 2.0 in persons with chronic low back pain.

Chiropr Man Therap

December 2023

Institute for Disability and Rehabilitation Research, Faculty of Health Sciences, Ontario Tech University, 2000 Simcoe Street North, Oshawa, ON, L1G 0C5, Canada.

Background: The World Health Organization Disability Assessment Schedule 2.0 12-item survey (WHODAS-12) is a questionnaire developed by the WHO to measure functioning across health conditions, cultures, and settings. WHODAS-12 consists of a subset of the 36 items of WHODAS-2.

View Article and Find Full Text PDF

Characteristics, treatment patterns and retention with extended-release subcutaneous buprenorphine for opioid use disorder: A population-based cohort study in Ontario, Canada.

Drug Alcohol Depend

January 2024

Li Ka Shing Knowledge Institute of St. Michael's Hospital, 30 Bond Street, Toronto, Ontario M5B 1W8, Canada; University of Toronto Leslie Dan Faculty of Pharmacy, 144 College StToronto, Ontario M5S 3M2, Canada; ICES, V1 06, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada; University of Toronto Institute for Health Policy, Management and Evaluation,  155 College St 4th Floor, Toronto Ontario M5T 3M6, Canada. Electronic address:

Background: Uptake and retention for opioid agonist treatment (OAT) remains low. Novel extended-release formulations may improve OAT accessibility by reducing the frequency of healthcare visits. Our aim was to examine uptake, characteristics, treatment patterns and retention of individuals initiating extended-release subcutaneous buprenorphine (BUP-ER), a monthly injectable OAT.

View Article and Find Full Text PDF

Reducing disease prevalence rather than promoting health has long been the objective of significant population health initiatives, such as the social determinants of health (SDH) framework. However, empirical evidence suggests that people with diagnosed diseases often answer the self-reported health (SRH) question positively. In pursuit of a better proxy to understand, measure and improve health, this scoping review of reviews examines the potential of SRH to be used as an outcome of interest in population health policies.

View Article and Find Full Text PDF

Expanding access to high-cost medicines under the Universal Health Coverage scheme in Thailand: review of current practices and recommendations.

J Pharm Policy Pract

November 2023

Health Intervention and Technology Assessment Program (HITAP), Department of Health, Ministry of Public Health, 6th Floor, 6th Building, Tiwanon Road, Nonthaburi, 11000, Thailand.

Background: There has been an increasing demand to reimburse high-cost medicines, through public health insurance schemes in Thailand.

Methods: A mixed method approach was employed. First, a rapid review of select high-income countries was conducted, followed by expert consultations and an in-depth review of three countries: Australia, England and Republic of Korea to understand reimbursement mechanisms of high-cost medicines.

View Article and Find Full Text PDF

Purpose: Workplace support needs for women and men living with mental health conditions are not well understood. This study examined workplace accommodation and support needs among women and men with and without mental health or cognitive conditions and individual and workplace factors associated with having unmet needs.

Methods: A cross-sectional survey of 3068 Canadian workers collected information on disability, gender, gendered occupations, job conditions, work contexts, and workplace accommodations.

View Article and Find Full Text PDF

Trajectories of patients relisted for liver transplantation.

Ann Hepatol

January 2024

University Health Network, 585 University Avenue, Toronto, M5G 2N2, Canada; University of Toronto, 27 King's College Clr, Toronto, M5S 1A1, Canada; Toronto General Hospital Research Institute, 200 Elizabeth Street, Toronto, M5G 2C4, Canada. Electronic address:

Introduction And Objectives: Recurrent cirrhosis complicates 10-30% of Liver transplants (LT) and can lead to consideration for re-transplantation. We evaluated the trajectories of relisted versus primary listed patients on the waitlist using a competing risk framework.

Materials And Methods: We retrospectively examined 1,912 patients listed for LT at our centre between from 2012 to 2020.

View Article and Find Full Text PDF

Bridging ethics and epidemiology: Modelling ethical standards of health equity.

SSM Popul Health

December 2023

School of Health Studies, Faculty of Health Sciences, Western University, 1151 Richmond Street, London, ON, N6A 3K7, Canada.

Health inequities are differences in health that are 'unjust'. Yet, despite competing ethical views about what counts as an 'unjust difference in health', theoretical insights from ethics have not been systematically integrated into epidemiological research. Using diabetes as an example, we explore the impact of adopting different ethical standards of health equity on population health outcomes.

View Article and Find Full Text PDF