8 results match your criteria: "12296New York University School of Medicine[Affiliation]"

Background: There has been a significant increase in methamphetamine use among persons who use drugs in Vietnam in the last 5-10 years. We examined the degree to which adherence to antiretroviral therapy (ART) mediates the relationship between recent methamphetamine use and unsuppressed HIV viral load among people who inject drugs (PWID) in Hai Phong, Vietnam.

Methods: We recruited PWID from October 2016-October 2018 and enrolled HIV positive PWID into a cohort, with up to three years of total follow-up.

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: This study describes and demonstrates the applicability of a novel in silico method for modeling progressive carotid artery stenosis using the oscillatory shear index (OSI) as the basis of stenosis. : Three-dimensional reconstructions of 11 carotid arteries were generated using patient-derived magnetic resonance angiography and duplex ultrasound data. Computational fluid dynamic simulations were sequentially generated following computational stenosis assessment, and corresponding changes in OSI were observed and used as measure of morphological stabilization.

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Efficiency of a randomized confirmatory basket trial design constrained to control the family wise error rate by indication.

Stat Methods Med Res

July 2022

Department of Biostatistics, Bioinformatics and Biomathematics, Lombardi Comprehensive Cancer Center, 12231Georgetown University Medical Center, Washington, DC, USA.

Basket trials pool histologic indications sharing molecular pathophysiology, improving development efficiency. Currently, basket trials have been confirmatory only for exceptional therapies. Our previous randomized basket design may be generally suitable in the resource-intensive confirmatory phase, maintains high power even with modest effect sizes, and provides nearly -fold increased efficiency for indications, but controls false positives for the pooled result only.

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The electric stimulation provided by current cochlear implants (CI) is not power efficient. One underlying problem is the poor efficiency by which information from electric pulses is transformed into auditory nerve responses. A novel stimulation paradigm using ramped pulse shapes has recently been proposed to remedy this inefficiency.

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Outpatient antimicrobial stewardship programs (ASPs) are becoming increasingly prevalent in healthcare. Many programs have demonstrated the effectiveness of pharmacist-driven outpatient consultations or follow-up programs to ensure appropriate antimicrobial prescribing. However, there is a paucity of literature describing multidisciplinary approaches in large healthcare systems for patients discharged from the emergency department (ED).

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Machine learning algorithms are increasingly used in the clinical literature, claiming advantages over logistic regression. However, they are generally designed to maximize the area under the receiver operating characteristic curve. While area under the receiver operating characteristic curve and other measures of accuracy are commonly reported for evaluating binary prediction problems, these metrics can be misleading.

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Purpose: This study describes the frequency of JUUL e-cigarette (referred to as JUUL) quit attempts and identifies characteristics associated with confidence in quitting and perceived difficulty quitting JUUL.

Design: Cross-sectional study from a self-administered online survey.

Setting: Two public southern California universities.

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Objectives: The objective of this study is to identify contextual access factors to home and community health services for end-of-life support for older adults with serious life-limiting illness, as well as determine if access to home and community services is associated with health-care utilization.

Design: This study includes an environmental scan, grey literature review, qualitative interviews, and health-care utilization analysis. This study is a subproject of the Grudzen et al.

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