4 results match your criteria: "117980The Third Affiliated Hospital of Guangzhou Medical University[Affiliation]"
Molecular Epidemiology and Hematologic Characterization of Thalassemia in Guangdong Province, Southern China.
Clin Appl Thromb Hemost
August 2022
Department of Obstetrics and Gynecology, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, 117980The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
About 2% of the population in the world are carriers of the thalassemia gene. Thalassemia is highly prevalent in Southern China, and traditional clinical testing methods would cause missed diagnosis of partial static thalassemia. Here, we reviewed and summarized a set of simple and clinically feasible thalassemia detection protocols adopted by the Prenatal Diagnosis and Reproductive Center of our hospital.
View Article and Find Full Text PDFElevated apoptosis and abnormal apoptosis signaling of regulatory T cells in patients with systemic lupus erythematosus.
Lupus
October 2022
Department of Dermatology, Southwest Hospital, PLA, 12525Third Military Medical University, Chongqing, China.
In systemic lupus erythematosus (SLE), immune tolerance is influenced by defects in naturally occurring T cells (Tregs). To investigate the apoptosis rate of Tregs and their suppressive activity in patients with SLE and then to recognize the genes and signaling pathways that cause Treg apoptosis. FACS was used to assess the frequency and apoptosis rates of Tregs in 48 SLE patients and 28 normal controls (NCs).
View Article and Find Full Text PDFMagnetic resonance imaging thicknesses and apparent diffusion coefficient values of the endometrium and junction zone in women of reproductive age.
Acta Radiol
March 2023
Personnel Department, Shantou Chenghai District Chronic Disease Prevention and Treatment Station, Guangdong Province, Shantou, PR China.
Background: The endometrium and uterine junction zone often change throughout the menstrual cycle. Some pathological conditions may appear normal in uterine imaging, which will lead to missed diagnosis and misdiagnosis.
Purpose: To evaluate the changes in the thickness and apparent diffusion coefficient (ADC) values of the endometrium and uterine junction zone throughout the menstrual cycle in magnetic resonance imaging (MRI) of women of reproductive age.
Insulin-like growth factor reduced against decabromodiphenyl ether-209-induced neurodevelopmental toxicity in vivo and in vitro.
Hum Exp Toxicol
December 2021
Department of Obstetrics and Gynecology, Department of Fetal Medicine and Prenatal Diagnosis, Key Laboratory for Major Obstetric Diseases of Guangdong Province, 117980The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Objective: How to reduce the neurodevelopmental toxicity of decabromodiphenyl ether PBDE-209 remains unclear. This study investigated neurodevelopmental toxicity of PBDE-209 and the protective effects of insulin-like growth factor-1 (IGF-1).
Methods: Pregnant Sprague-Dawley rats were treated with PBDE-209 and IGF-1, and the offspring were subjected to the Morris Water Maze test.