1 results match your criteria: "1083 HV Amsterdam (The Netherlands). rtdame@chem.leidenuniv.nl.[Affiliation]"

Single-molecule unzipping force analysis of HU-DNA complexes.

Chembiochem

October 2013

Leiden Institute of Chemistry and Cell Observatory, Leiden University, Einsteinweg 55, 2333 CC Leiden (The Netherlands); Department of Physics and Astronomy, VU University, De Boelelaan 1083, 1083 HV Amsterdam (The Netherlands).

The genome of bacteria is organized and compacted by the action of nucleoid-associated proteins. These proteins are often present in tens of thousands of copies and bind with low specificity along the genome. DNA-bound proteins thus potentially act as roadblocks to the progression of machinery that moves along the DNA.

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