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Quantitative trait loci affecting the behavior of A/J and CBA/J intercross mice in the elevated plus maze.

Mamm Genome

July 2001

Laboratory of Cerebral Metabolism and Geriatric Psychiatry Branch, National Institute of Mental Health, NIH, Bldg. 10, Room 3N218, 10 Center Dr. MSC 1274, Bethesda, Maryland, 20892-1274, USA.

How allelic diversity affects neural mechanisms to produce behavioral variation is largely unknown. The elevated plus maze, consisting of open and closed arms, has been used as a model of behavioral variation in rodent exploration. Under dim illumination the nature of the sensory stimuli that influence arm choice is uncertain.

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