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1 Upstate Community Hospital[Affiliation] Publications | LitMetric

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Article Synopsis
  • Cholinesterase (ChE) inhibitors are used for treating Alzheimer's symptoms, but hospitalization often includes anticholinergic medications that counteract these inhibitors.
  • A study analyzed the effect of high anticholinergic burden (ACB) on hospital length of stay (LOS) and 30-day readmissions for patients taking ChE inhibitors during their hospital stay.
  • Results showed that patients with high ACB experienced a significantly longer hospital stay (5.50 days vs 4.25 days), but the 30-day readmission rate difference was not statistically significant (6.8% vs 2.2%).
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Parkinson's disease (PD) is a debilitating condition that affects 1.8% of people 65 years of age and older. Patients with PD often require hospitalization and are frequently admitted through the emergency department (ED).

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Currently, our institution does not have a full-time pharmacist rounding with the inpatient acute care of the elderly (ACE) team daily. We sought to evaluate the involvement of a clinical pharmacy service within the ACE team and its impact on appropriate medication use. The primary outcome was the number of drug-related problems (DRPs) and potentially inappropriate medications (PIMs) detected by the pharmacist compared with no pharmacist on the ACE team.

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