Adult ADHD Is Associated With Gambling Severity and Psychiatric Comorbidity Among Treatment-Seeking Problem Gamblers.

The aim of this study is as follows: (a) exploring retrospective childhood and adult ADHD symptomatology in treatment-seeking gamblers, (b) providing detailed characteristics of the association between pathological gambling (PG) and ADHD, and (c) identifying risk factors for a history of ADHD. Eighty problem gamblers (20% female) were examined using a standardized interview (PG: [4th ed.; ] criteria, Gambling Attitudes and Beliefs Survey; ADHD: Wender Utah Rating Scale-, Adult ADHD Self-Report Scale; comorbidities: Mini International Neuropsychiatric Interview).

Virtual Screening of DrugBank Reveals Two Drugs as New BCRP Inhibitors.

The breast cancer resistance protein (BCRP) is an ABC transporter playing a crucial role in the pharmacokinetics of drugs. The early identification of substrates and inhibitors of this efflux transporter can help to prevent or foresee drug-drug interactions. In this work, we built a ligand-based in silico classification model to predict the inhibitory potential of drugs toward BCRP.

Footedness Is Associated With ADHD Symptoms in the Adult General Population.

Objective: Mixed-handedness among children has recently been proposed as a marker of neurodevelopmental disorder and ADHD. This study expanded this initial evidence to the questions of whether mixed-handedness as well as mixed-footedness are similarly associated with ADHD among adults.

Method: Self-reported ADHD symptoms, handedness, footedness, and current depression and anxiety were assessed in a large, heterogeneous general population sample ( N = 2,592).