Adsorbing Volatile Organic Chemicals by Soluble Triazine-Based Dendrimers under Ambient Conditions with the Adsorption Capacity of Pyridine up to 946.2 mg/g.

Two triazine-based dendrimers with peripheral 1,3,5-triamidobenzene (1-3-5-TAB) functionality were prepared, and their void spaces in the bulk solid were investigated. We examined dendrimers of three core lengths and determined the one with the longest core exhibits the largest void space because the peripheral amides were not imbedded in the internal space of each dendritic molecule. The new dendrimers as solids were observed to adsorb volatile organic chemicals efficiently.

Computer-Assisted System in Stress Radiography for Anterior Cruciate Ligament Injury with Correspondent Evaluation of Relevant Diagnostic Factors.

We sought to design a computer-assisted system measuring the anterior tibial translation in stress radiography, evaluate its diagnostic performance for an anterior cruciate ligament (ACL) tear, and assess factors affecting the diagnostic accuracy. Retrospective research for patients with both knee stress radiography and magnetic resonance imaging (MRI) at our institution was performed. A complete ACL rupture was confirmed on an MRI.

CBM drilling technical parameter optimization methodology and software development: a case study of LUAN mining area.

Based on the leakage of the coalbed methane (CBM) drilling engineering practice of Luan mining area in China, the author determines the safe drilling fluid density range for the stable borehole wall based on borehole wall collapse and fracture pressure. Such parameters as the drilling fluid hydraulic parameters (including pump pressure, pump power and displacement, nozzle diameter, bit pressure drop, bit hydraulic horsepower, circulation pressure drop, impact force and jet velocity) and drilling parameters (including weight-on-bit, drilling rotary speed, bit tooth wear) in each borehole section are optimized. Taking the lowest drilling cost as the controlling target, the drilling parameter optimization model is designed and solved by the genetic algorithm.

The Relationship between Clinic Visit Accompanied by Family and Dementia Severity in Taiwan.

Introduction: This study analyzes the severity of dementia status with clinical dementia rating (CDR) score distribution among patients according to various family functional and sociodemographic issues.

Methods: A cross-sectional study was performed in a regional hospital in Central Taiwan. The sample consisted of 318 patients who came to the clinic from May 2018 to April 2019, and who were diagnosed by the physicians with CDR scores ≧ 0.

Rottlerin, BDNF, and the impairment of inhibitory avoidance memory.

Rationale And Objective: As a eukaryotic elongation factor 2 kinase (eEF2K) inhibitor and a mitochondrial uncoupler, oncologists have extensively studied rottlerin. Neuroscientists, however, have accumulated scarce data on the role of rottlerin in affective and cognitive functions. Only two prior studies have, respectively, documented its antidepressant-like effect and how it impairs psychostimulant-supported memory.

Approaching environmental human thermophysiological thresholds for the case of Ankara, Turkey.

The disclosed study undertook a 'human centred-approach' that ascertained and categorised environmental human thermophysiological risk factors by relating them to the human biometeorological system through the use of three widely utilised energy balance model (EBM) indices, the physiologically equivalent temperature (PET), the modified PET, and the universal thermal climate index (UTCI). The disclosed assessment was carried out over the past decade (i.e.

Naturally derived DNA nanogels as pH- and glutathione-triggered anticancer drug carriers.

Conventional chemotherapeutic drugs are nonselective and harmful toward normal tissues, causing severe side effects. Therefore, the development of chemotherapeutics that can target cancer cells and improve therapeutic efficacy is of high priority. Biomolecules isolated from nature serve as green solutions for biomedical use, solving biocompatibility and cytotoxicity issues in human bodies.

Association of the Hepatitis B Virus Large Surface Protein with Viral Infectivity and Endoplasmic Reticulum Stress-mediated Liver Carcinogenesis.

Hepatitis B is the most prevalent viral hepatitis worldwide, affecting approximately one-third of the world's population. Among HBV factors, the surface protein is the most sensitive biomarker for viral infection, given that it is expressed at high levels in all viral infection phases. The large HBV surface protein (LHBs) contains the integral pre-S1 domain, which binds to the HBV receptor sodium taurocholate co transporting polypeptide on the hepatocyte to facilitate viral entry.

The anti-TH17 polarization effect of Indigo naturalis and tryptanthrin by differentially inhibiting cytokine expression.

Ethnopharmacological Relevance: The Chinese herbal medicine Qing-Dai (also known as Indigo naturalis) extracted from indigo-bearing plants including Baphicacanthus cusia (Ness) Bremek was previously reported to exhibit anti-psoriatic effects in topical treatment. TH17 was later established as a key player in the pathogenesis of psoriasis. We investigated the anti-TH17 effect of Indigo naturalis and its active compounds.

Temporal physicochemical changes and transformation of biochar in a rice paddy: Insights from a 9-year field experiment.

Biochar application to soil has attracted extensive attention worldwide due to its carbon (C) sequestration and fertility-enhancing properties. However, the lack of biochar accumulation in highly disturbed agroecosystems challenges the perceived long-term stability of biochars in soil. This 9-year field experiment was conducted in rice paddy fields to understand the temporal degradation of biochars produced from two contrasting feedstocks (rice straw vs.

Biochar drives microbially-mediated rice production by increasing soil carbon.

The effects of an on-site biomass (rice straw) equivalent biochar-returning strategy (RSC) on rice yield, soil nutrients and bacterial community composition were examined in a four-year field trial (2013-2016) conducted in a paddy field in south China. Three treatments were set up including annual on-site biomass return (RS, rice straw at 8 t ha yr), annual on-site biomass equivalent biochar-return (RSC, rice straw biochar at 2.8 t ha yr with a 35 % carbonization rate) and control (CK, no rice straw or biochar added).

In-mold and Machine Sensing and Feature Extraction for Optimized IC-tray Manufacturing.

Injection molding is a mature technology that has been used for decades; factors including processed raw materials, molds and machines, and the processing parameters can cause significant changes in product quality. Traditionally, researchers have attempted to improve injection molding quality by controlling screw position, injection and packing pressures, and mold and barrel temperatures. However, even when high precision control is applied, the geometry of the molded part tends to vary between different shots.

Tie-Bar Elongation Based Filling-To-Packing Switchover Control and Prediction of Injection Molding Quality.

Filling-to-packing switchover (also called V/P switchover) is critical for assuring injection molding quality. An improper V/P switchover setting may result in various defects of injection-molded parts, such as excessive residual stress, flash, short shot, and warpage, etc. To enhance a consistent molding quality, recent V/P switchover approaches adopt cavity pressure profiles requiring sensors embedded in mold cavities, which is invasive to mold cavities and more expensive.

Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data.

Background: This study estimated the long-term changes of opioid agonist treatment (OAT) in quality of life (QOL) and quantified the quality-adjusted life years (QALY) from the loss of quality-adjusted life expectancy (QALE) in heroin users.

Methods: A total of 1283 heroin users stratified by OAT were linked to the National Mortality Registry for 8 years (2006-2014) to obtain survival functions, which were extrapolated to lifetime by applying a rolling extrapolation algorithm to survival ratio between the sub-cohorts and age- and sex-matched referents simulated from vital statistics of Taiwan. We performed cross-sectional measurement of EQ-5D on 349 participants, including those with a valid state of OAT or non-OAT plus newly recruited consecutive patients, during 2015-2017 for utility values, while the QOL of referents were abstracted from the 2009 National Health Interview Survey.

The application of a high-density street-level air temperature observation network (HiSAN): The relationship between air temperature, urban development, and geographic features.

The urban heat island effect in cities has become an important problem in relation to not only urban climate but also public health and urban planning. Tainan, which located in Southern Taiwan, is a compact city with intense development. Therefore, this study investigated the urban thermal condition by employing a high-density street-level air temperature observation network (HiSAN).

Evaluate five different diagnostic tests for dry mouth assessment in geriatric residents in long-term institutions in Taiwan.

Background: Residents in long-term care (LTC) institutions require care plans to effectively resolve dry mouth. Simple and easily comprehensible dry mouth indices must be developed to assist care professionals in determining dry mouth among residents. Therefore, this study aim of the study was to evaluate five different diagnostic tests for dry mouth assessment.

The biochemical and electrophysiological profiles of amniotic fluid-derived stem cells following Wnt signaling modulation cardiac differentiation.

Owing to the beneficial properties of amniotic fluid-derived stem cells (AFSCs), including pluripotency and the lack of ethical issues associated with embryonic stem cells (ESCs), they should be a promising cell source for regenerative medicine. However, how to differentiate AFSCs into contracting cardiomyocytes has not been established. In this study, a well-established, direct cardiac differentiation protocol involving the modulation of Wnt signaling was used to differentiate Oct 3/4 AFSCs into cardiomyocytes.

Osteochondral Tissue Regeneration Using a Tyramine-Modified Bilayered PLGA Scaffold Combined with Articular Chondrocytes in a Porcine Model.

Repairing damaged articular cartilage is challenging due to the limited regenerative capacity of hyaline cartilage. In this study, we fabricated a bilayered poly (lactic-co-glycolic acid) (PLGA) scaffold with small (200⁻300 μm) and large (200⁻500 μm) pores by salt leaching to stimulate chondrocyte differentiation, cartilage formation, and endochondral ossification. The scaffold surface was treated with tyramine to promote scaffold integration into native tissue.

Using Internet Search Trends and Historical Trading Data for Predicting Stock Markets by the Least Squares Support Vector Regression Model.

Historical trading data, which are inevitably associated with the framework of causality both financially and theoretically, were widely used to predict stock market values. With the popularity of social networking and Internet search tools, information collection ways have been diversified. Instead of only theoretical causality in forecasting, the importance of data relations has raised.

Rap1 Negatively Regulates the Hippo Pathway to Polarize Directional Protrusions in Collective Cell Migration.

In collective cell migration, directional protrusions orient cells in response to external cues, which requires coordinated polarity among the migrating cohort. However, the molecular mechanism has not been well defined. Drosophila border cells (BCs) migrate collectively and invade via the confined space between nurse cells, offering an in vivo model to examine how group polarity is organized.

Identifying outdoor thermal risk areas and evaluation of future thermal comfort concerning shading orientation in a traditional settlement.

The outdoor thermal environment is expected to be deteriorated under climate change. An approach of risk identification including assessment from aspects of thermal stress effect, people's exposure, and local's vulnerability were adopted to study a hot-and-humid traditional rural community located at Tainan, Taiwan. Layers of each aspect were either constructed by in-situ measurements or simulations.

The application of a high-density street-level air temperature observation network (HiSAN): Dynamic variation characteristics of urban heat island in Tainan, Taiwan.

The effects of urban heat island (UHI) have recently become a crucial issue. This study utilized a high-density street-level air temperature observation network (HiSAN) to understand the UHI characteristics in Tainan City. A total of 100 measurement points were established throughout the city.

The Complex Relations Between Wisdom and Significant Life Learning.

This study explores the various relations between two important processes in life-span development: wisdom and learning from significant life experience. A diverse sample of 375 individuals from Taiwan, culled from an initial sample of 475, completed a sequence of three questionnaires that asked them to describe their most significant life learning, the wisdom they had displayed, and the relation between the two. The 375 participants specified one of five relations: (a) their most significant life learning led to their display of wisdom ( = 191, 51%); (b) the two were unrelated ( = 91, 24%); (c) their display of wisdom led to their most significant life learning ( = 67, 18%); (d) the wisdom displayed was part of their most significant life learning ( = 20, 5%); (e) their most significant life learning was part of the wisdom they displayed ( = 6, 2%).