Establishing MRI-guided prostate intervention at a UK Centre.

Objectives: To describe our preliminary experience in establishing an MRI suite capable to deliver targeted prostate biopsy and cryoablation.

Methods: This article includes a description of the necessary infrastructure alterations, scanning sequence suggestions, anaesthetic advice, and practical procedural considerations. We aim to examine the anticipated issues most UK centres would encounter and offer our experience in overcoming them.

Impact of cardiopulmonary bypass surgery on cytokines in epicardial adipose tissue: comparison with subcutaneous fat.

Background: Cardiac surgery and cardiopulmonary bypass (CPB) have been shown to stimulate a systemic inflammatory response which has been associated with adverse postoperative outcomes. Adipose tissue, both epicardial (EAT) and subcutaneous (SAT), is a known source of inflammatory cytokines, but its role in the pathophysiology of surgery- and CPB-induced systemic inflammatory response has not been fully elucidated. Therefore, we conducted a study to establish levels of selected cytokines in EAT and SAT prior to and after surgery with CPB.