4 results match your criteria: "1 Universitatii Alley[Affiliation]"

Evaluation of MELD Scores and Thyroid Hormones as Prognostic Factors of Liver Cirrhosis.

Medicina (Kaunas)

September 2024

Faculty of Medicine, Ovidius University of Constanta, 1 Universitatii Alley, 900470 Constanta, Romania.

Article Synopsis
  • Hepatic cirrhosis is increasingly common worldwide, but its development mechanisms are not fully understood; this study aimed to link thyroid hormone levels (T3, fT4, and TSH) with survival in chronic liver disease patients.
  • The study involved 419 patients with liver cirrhosis, using the MELD score and ELISA procedures to analyze thyroid hormone levels and confirm diagnoses through clinical symptoms and tests.
  • Results showed a positive correlation between MELD scores and TSH levels; patients who did not survive had higher TSH levels, while T3 and fT4 changes were not significant, suggesting TSH could be an important marker for monitoring liver cirrhosis progression.
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: Calprotectin is a marker for intestinal inflammation. Recent research suggests a link between inflammation and depression. This study assessed the association between the levels of calprotectin in patients from South-Eastern Europe and the severity of depression, anxiety, and quality of life.

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Objective: The present study aims to estimate the public cost of depression in Romania during a seven-year time span to complement existing papers with data from Central and Eastern Europe and to identify and propose measures that allow efficient use of funds.

Methods: We used data collected from the National Health Insurance System to analyze the main components of the cost.

Findings: Indirect costs exceed direct costs.

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Depression is a global health problem that requires an early and accurate diagnosis to ensure quick access to appropriate treatment. Among multiple psychopathological paths, recent attention has focused on analysing the brain-gut-microbiota axis. The intestinal barrier plays a key role, and dysfunctions occurring at this level have implications for mental health.

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