2 results match your criteria: "1 Tokyo Women's Medical University[Affiliation]"
In Vivo Antitumor Effects of MK615 Led by PD-L1 Downregulation.
Integr Cancer Ther
September 2018
1 Tokyo Women's Medical University, Tokyo, Japan.
Background/aim: MK615 extracted from Prunus mume was reported to have anti-inflammatory effects. In this article, we examined the in vivo antitumor effect of MK615 (an extract from Japanese apricot) using mouse tumor xenografts and focusing on the downregulation of PD-L1 (programmed death-ligand 1), a ligand of programmed cell death-1, a surface protein of activated T cells.
Materials And Methods: B16/BL6 melanoma cells were injected into C57BL/6 or BALB/c-nu/nu mice to establish lung metastasis.
Outcomes of Kidney Transplantation from Circulatory Death Donors With Increased Terminal Creatinine Levels in Serum.
Transplantation
July 2016
1 Tokyo Women's Medical University, Department of Surgery III, Tokyo, Japan. 2 International University of Health and Welfare, Atami Hospital, Department of Transplant Surgery, Shizuoka, Japan.
Background: To alleviate chronic renal graft shortages in Japan, donation after circulatory death (DCD) is an increasingly used organ resource. Organs from DCD donors with progressively increased terminal creatinine (t-Cr) levels are frequently used, but the effects of this condition on kidney transplantation (KTx) remain unclear.
Methods: Between 1996 and 2013, 99 KTx from DCD donors were conducted in our department.