1 results match your criteria: "1 Shanghai Institute of Ceramics[Affiliation]"
Influence of patterned titanium coatings on polarization of macrophage and osteogenic differentiation of bone marrow stem cells.
J Biomater Appl
February 2018
1 Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, PR China.
Article Synopsis
- Biomaterial surface topography significantly influences how implants integrate with bone by affecting early cell responses and tissue development, with this study focusing on macrophage behavior rather than just osteogenic cells.
- * The research found that macrophages on patterned titanium coatings showed a preference for the anti-inflammatory M2 polarization, leading to increased expression of anti-inflammatory genes compared to those on traditional coatings, which leaned towards the pro-inflammatory M1 polarization.
- * Patterned titanium surfaces not only promoted better macrophage behavior but also enhanced osteogenic activity in bone marrow stem cells, suggesting that using patterned surfaces can improve the immune response and support bone healing around implants.