11 results match your criteria: "1 Joslin Diabetes Center[Affiliation]"
Asian Americans have a higher prevalence of developing type 2 diabetes mellitus (T2DM) compared with White Americans. A two-phase evidence-based project developed specifically for Chinese American employees at an urban catering company worksite was led by a registered nurse/certified diabetes educator. The purpose of this project was to (a) identify Chinese employees at risk for T2DM, and (b) develop and implement a customized diabetes prevention program in Chinese.
View Article and Find Full Text PDFJ Diabetes Sci Technol
November 2018
3 Abbott Diabetes Care, Alameda, CA, USA.
Background: The goal of this uncontrolled pilot study was to assess the feasibility of a self-care management mobile app, called Sugar Sleuth, which incorporates the FreeStyle Libre™ glucose sensor, to help clinicians and people with type 1 diabetes (PWD) identify and mitigate self-care behaviors that contribute to glucose variability.
Methods: PWDs with a baseline A1c between 7.5 and 9.
J Diabetes Sci Technol
September 2017
1 Joslin Diabetes Center, Boston, MA, USA.
Background: This study investigated unique burdens experienced by parents of young children with type 1 diabetes in the context of contemporary diabetes management.
Methods: Self-report surveys and medical record information from the T1D Exchange clinic registry were used. Parental burden and family impact scores were tabulated across demographic and clinical characteristics, overall and according to age group (<4, 4-<6, and 6-<7 years).
J Diabetes Sci Technol
February 2017
1 Joslin Diabetes Center, Boston, MA, USA.
Diabetes Technol Ther
June 2017
1 Joslin Diabetes Center , Harvard Medical School, Boston, Massachusetts.
Background: Managing type 1 diabetes (T1D) in young children presents challenges to families and caregivers. Pump therapy may reduce challenges and benefit glycemic control. However, pump use is not universal; parent-reported reasons for lack of uptake are not well described.
View Article and Find Full Text PDFDiabetes Technol Ther
October 2016
1 Joslin Diabetes Center, Boston, Massachusetts.
Background: The cost of diabetes care accounts for a significant proportion of healthcare expenditures. Cost models based on updated incident complication rates and associated costs are needed to improve financial planning and quality assessment across the U.S.
View Article and Find Full Text PDFDiabetes Technol Ther
February 2016
4 MIT Media Lab , Cambridge, Massachusetts.
Background: Overseeing proper insulin initiation and titration remains a challenging task in diabetes care. Recent advances in mobile technology have enabled new models of collaborative care between patients and healthcare providers (HCPs). We hypothesized that the adoption of such technology could help individuals starting basal insulin achieve better glycemic control compared with standard clinical practice.
View Article and Find Full Text PDFTelemed J E Health
December 2015
1 Joslin Diabetes Center, SUNY Upstate Medical University, Syracuse, New York.
Background: The Informatics for Diabetes Education and Telemedicine (IDEATel) project demonstrated that a telemedicine intervention can improve glycemic, lipid, and blood pressure control. The focus of the current study was to evaluate factors associated with primary care providers' (PCPs') decision on whether to follow recommendations from the remote diabetes team in Upstate New York.
Materials And Methods: In the intervention group, diabetes educators videoconferenced with patients monthly to download and review glucose and blood pressure readings, diabetes-related issues, and laboratory data.
Nat Med
April 2015
1] Diabetes Center, University of California, San Francisco (UCSF), San Francisco, California, USA. [2] Department of Cell and Tissue Biology, UCSF, San Francisco, California, USA. [3] Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, California, USA.
Brown adipose tissue (BAT) acts in mammals as a natural defense system against hypothermia, and its activation to a state of increased energy expenditure is believed to protect against the development of obesity. Even though the existence of BAT in adult humans has been widely appreciated, its cellular origin and molecular identity remain elusive largely because of high cellular heterogeneity within various adipose tissue depots. To understand the nature of adult human brown adipocytes at single cell resolution, we isolated clonally derived adipocytes from stromal vascular fractions of adult human BAT from two individuals and globally analyzed their molecular signatures.
View Article and Find Full Text PDFNature
March 2015
1] Joslin Diabetes Center, One Joslin Place, Boston, Massachusetts 02215, USA [2] Harvard Stem Cell Institute, 7 Divinity Avenue, Cambridge, Massachusetts 02138, USA [3] Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02215, USA.
Interventions that delay ageing mobilize mechanisms that protect and repair cellular components, but it is unknown how these interventions might slow the functional decline of extracellular matrices, which are also damaged during ageing. Reduced insulin/IGF-1 signalling (rIIS) extends lifespan across the evolutionary spectrum, and in juvenile Caenorhabditis elegans also allows the transcription factor DAF-16/FOXO to induce development into dauer, a diapause that withstands harsh conditions. It has been suggested that rIIS delays C.
View Article and Find Full Text PDFDiabetes Technol Ther
December 2014
1 Joslin Diabetes Center, Boston, Massachusetts.