3 results match your criteria: "1 Carol Davila University of Medicine and Pharmacy[Affiliation]"
The importance of the enzyme Gamma-glutamyltransferase in the pathogenic cluster in type2 diabetic patient.
Rom J Intern Med
June 2024
2National Institute of Diabetes, Nutrition and Metabolic Diseases, Bucharest, Romania.
Article Synopsis
- Gamma-glutamyltransferase (GGT) is a liver enzyme that indicates inflammation and oxidative stress, and its levels are elevated in type 2 diabetes, particularly in patients with dysglycaemia and dyslipidemia.
- The study involved 85 type 2 diabetes patients aged 40-70 years, divided into subgroups based on GGT levels, revealing that those with high GGT exhibited higher inflammatory markers and signs of endothelial dysfunction.
- The findings suggest that in non-alcoholic diabetic patients with less than 6 years of diabetes, elevated GGT levels, along with markers like sICAM, serum MCP-1, and TNF-α, may signal significant metabolic issues.
Factor XI and coagulation. Factor XI inhibitors - antithrombotic perspectives.
Rom J Intern Med
June 2024
2"Carol Davila" University of Medicine and Pharmacy, Department of Functional Sciences, Division of Physiology, Bucharest, Romania.
Factor XI is a zymogen with an important role in the coagulation cascade. It is activated by FXII, thrombin and or it can be autoactivated. It has a prothrombotic effect after being activated by thrombin, but also through its antifibrinolytic action, stabilizing the formed clot.
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