1,751 results match your criteria: "08025 Barcelona Spain; Josep Carreras Leukaemia Research Institute (IJC)[Affiliation]"
3D Print Med
December 2024
Diagnostic Imaging Department, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025, Barcelona, Spain.
Background: 3D technologies [Virtual and Augmented 3D planning, 3D printing (3DP), Additive Manufacturing (AM)] are rapidly being adopted in the healthcare sector, demonstrating their relevance in personalized medicine and the rapid development of medical devices. The study's purpose was to understand the state and evolution of 3DP/AM technologies at the Point-of-Care (PoC), its adoption, organization and process in Spanish hospitals and to understand and compare the evolution of the models, clinical applications, and challenges in utilizing the technology during the COVID-19 pandemic and beyond.
Methods: This was a questionnaire-based qualitative and longitudinal study.
J Pers Med
November 2024
Otorhinolaryngology Department, Hospital Clinic of Barcelona, Universitat de Barcelona (UB), 08036 Barcelona, Spain.
: Sinonasal mucosal melanomas (SNMMs) are rare and aggressive malignancies with poor survival outcomes. Our systematic review and meta-analysis aim to evaluate overall survival (OS) rates in patients with SNMM; : We conducted a systematic search, following PRISMA guidelines across PubMed, Web of Science (WOS), and citation searching for studies reporting survival and prognosis outcomes for SNMMs. Inclusion criteria included studies with 5-year OS rates.
View Article and Find Full Text PDFBMC Med
December 2024
Centre for Fertility and Health, Norwegian Institute of Public Health, Skøyen, PO Box 222, 0213, Oslo, Norway.
Background: Telomere length (TL) has been reported to be associated with conditions such as endometriosis and polycystic ovary syndrome, with some studies finding associations with shorter TL and others with longer TL. In men, studies mostly report associations between shorter TL and sperm quality. To our knowledge, no studies have thus far investigated associations between TL and fecundability or the use of assisted reproductive technologies (ART).
View Article and Find Full Text PDFJ Clin Med
November 2024
RedGDPS Foundation, 08204 Sabadell, Spain.
: This study aimed to assess the incidence of diabetic retinopathy (DR) in patients with type 2 diabetes (T2DM) treated in primary-care settings in Catalonia, Spain, and identify key risk factors associated with DR development. : A retrospective cohort study was conducted using the SIDIAP (System for Research and Development in Primary Care) database. Patients aged 30-90 with T2DM who underwent retinal screening between 2010 and 2015 were included.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
Facultat de Ciències de la Salut Blanquerna, Universitat Ramon Llull, 08025 Barcelona, Spain.
Background/objectives: During pregnancy, women can experience stress, anxiety, and insomnia, which affect their health and wellbeing. Since many conventional medications are contraindicated for pregnant women, there is a need to find alternative therapies for alleviating their discomfort. Lavender essential oil (EO) is recognized for its calming and relaxing properties; therefore, our goal was to review current knowledge of lavender EO use to reduce anxiety and stress as well as to improve sleep quality in pregnant women.
View Article and Find Full Text PDFNutrients
November 2024
Nephrology Department, Hospital Universitari Dr. J Trueta, 17007 Girona, Spain.
Background And Objective: To evaluate the effectiveness and safety of intradialytic parenteral nutrition (IDPN) on different nutritional outcomes.
Methods: This was a retrospective analysis for a "routinely collected data bank" in a multicenter cohort, conducted on consecutive malnourished or at-risk of malnutrition patients with chronic kidney disease on hemodialysis who underwent IDPN with a three-in-one parenteral nutrition formula for a period ≥ 2 weeks. The primary endpoint was the mean change in the malnutrition inflammation score (MIS) score between baseline and the last follow-up visit on IDPN.
Cancers (Basel)
December 2024
Colorectal Unit, Department of Surgery, La Paz University Hospital, 28046 Madrid, Spain.
Colorectal cancer (CRC) is a neoplasm with a high prevalence worldwide, with a multimodal treatment that includes a combination of chemotherapy, radiotherapy, and surgery in locally advanced stages with acceptable pathological complete response (pCR) rates, this has improved with the introduction of total neoadjuvant therapy (TNT) reaching pCR rates up to 37% in compare with classic neoadjuvant treatment (NAT) where pCR rates of around 20-25% are achieved. However, the patient population that benefits most from this therapy has not been determined, and there is a lack of biomarkers that can predict the course of the disease. Multiple biomarkers have been studied, ranging from hematological and molecular markers by imaging technique and combinations of them, with contradictory results that prevent their use in routine clinical practice.
View Article and Find Full Text PDFCancers (Basel)
November 2024
Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Background/objectives: Patients with relapsed/refractory (R/R) AML with mutation () have a dismal prognosis. offers a target for therapy in these patients. Gilteritinib (gilter) and quizartinib (quizar) have demonstrated efficacy as single agents in two phase 3 clinical trials.
View Article and Find Full Text PDFMil Med Res
December 2024
Department of Urology, University College Hospital of London, London, NW1 2BU, UK.
Brain Commun
October 2024
Neuro-Policy Program, Center for Health and Bioscience, Baker Institute for Public Policy, Rice University, Houston, TX 77006, USA.
Optimal brain health is essential to smoothing major global skill-intensive economic transitions, such as the bioeconomy, green, care economy and digital transitions. Good brain health is vital to socio-economic sustainability, productivity and well-being. The care transition focuses on recognizing and investing in care services and care work as essential for economic growth and social well-being.
View Article and Find Full Text PDFRespir Investig
December 2024
Servicio de Neumología, Hospital Universitario Gregorio Marañón, UCM, C. del Dr. Esquerdo, 46, Retiro, 28007, Madrid, Spain.
J Clin Epidemiol
December 2024
Institut de Recerca Sant Pau (IR SANT PAU), Sant Quintí 77-79, 08041, Barcelona, Spain; Centro Cochrane Iberoamericano, Sant Antoni Maria Claret, 167, 08025 Barcelona, Spain; CIBER de Epidemiología y Salud Pública, Instituto de Salud Carlos III (CIBERESP), Spain.
Objective: to assess the associations between cost-effectiveness analysis' (CEA) methodological characteristics and Incremental Cost-Effectiveness Ratio (ICER) outcomes and conclusions, in biological treatments for asthma.
Study Design And Setting: We included CEAs comparing biological treatments to standard care, in adults with severe asthma. We performed a search in MEDLINE, EMBASE, and Web of Science (Sep 2022).
J Clin Med
November 2024
Nephrology Department, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.
The document provides a comprehensive overview of the diagnosis, monitoring, and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with renal involvement, focusing on granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It outlines the definitions, clinical presentation, histopathological classification, monitoring strategies, induction and maintenance treatments, as well as special considerations for relapsing, refractory, and frail patients with renal AAV. The document was prepared by the Catalan Group for the Study of Glomerular Diseases (GLOMCAT), which comprises nephrologists with extensive experience in the diagnosis and treatment of AAV patients.
View Article and Find Full Text PDFBrain Sci
October 2024
Department of Neurosurgery, University Hospital La Princesa, 28006 Madrid, Spain.
Biomolecules
November 2024
Cardiac Rhythm and Contraction Group, Biomedical Research Institute of Barcelona (IIBB-CSIC), Rosselló 161, 08036 Barcelona, Spain.
Human atrial myocytes afford an attractive experimental model to investigate mechanisms underlying electrophysiological alterations in cardiovascular disease. However, this model presents limitations, such as the availability of human atrial tissue and a variable yield of myocytes isolation. Therefore, we aimed to determine whether overnight storage can increase the time window where the electrophysiological properties of human atrial myocytes can be determined.
View Article and Find Full Text PDFBiomolecules
November 2024
CIBERehd (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Frailty in cirrhosis or advanced chronic liver disease (ACLD) is a relevant prognostic factor. In the present study, we aimed to analyze potential biomarkers associated with frailty and its improvement in patients with ACLD. We analyzed the serum of outpatients with ACLD who participated in a previous study (Román, Hepatol Commun 2024) in which frailty was assessed using the liver frailty index (LFI), and patients who were frail or prefrail were randomized to a multifactorial intervention (home exercise, branched-chain amino acids, and probiotics) or control for 12 months.
View Article and Find Full Text PDFBiomolecules
October 2024
Laboratoire de Physique Théorique, Université de Toulouse, CNRS, UPS, 31062 Toulouse, France.
Myocardial fibrosis is a major pathologic disorder associated with a multitude of cardiovascular diseases (CVD). The pathogenesis is complex and encompasses multiple molecular pathways. Integration of fibrosis-associated genes into the global MetaCore network of protein-protein interactions (PPI) offers opportunities to identify PPI with functional and therapeutic significance.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2024
Department of Medicine, Universitat Autònoma de Barcelona (UAB), 08193 Barcelona, Spain.
Introduction: We conducted a comprehensive comparative analysis of the Okazaki, Umehara, and American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for diagnosing immunoglobulin G4-related disease (IgG4-RD).
Materials And Methods: A retrospective study was conducted in a single tertiary hospital, using expert clinical judgment as the gold standard. We compared the diagnostic accuracy of the Okazaki, Umehara, and ACR/EULAR criteria in a cohort of 41 patients with suspected IgG4-RD.
Toxins (Basel)
November 2024
Anemia Working Group of the Spanish Society of Nephrology, 39008 Santander, Spain.
J Healthc Qual Res
November 2024
Enginyeria Biomédica, Universitat Pompeu Fabra, Barcelona, Spain.
Introduction: Primary health care is essential in a well-designed health system. A way of approaching the quality of an institution or service is evaluating different aspects like accessibility, treatment, satisfaction, and efficiency. The COVID-19 pandemic caused substantial disruptions in health systems.
View Article and Find Full Text PDFEur J Pediatr
November 2024
Julius Center for Health Sciences and Primary Care, Department of Data Science & Biostatistics, University Medical Center Utrecht, Utrecht, The Netherlands.
Unlabelled: We aim to estimate the incidence rates (IRs) of SARS-CoV-2 infections stratified by disease severity and comorbidities in pediatric population and to describe the COVID-19 vaccination coverage in children with and without comorbidities. A population-based cohort study was conducted in 6 electronic healthcare records databases from Italy, Spain, and Norway. The study lasted from 1 January 2020 to the latest databases' available data in each site, i.
View Article and Find Full Text PDFInt J Mol Sci
October 2024
Department of Neurology, Donostia University Hospital, Dr Begiristain sn., 20003 San Sebastian, Spain.
Despite recent advances in treatment options, stroke remains a highly prevalent and devastating condition with significant socioeconomic impact. Recanalization therapies, including intravenous thrombolysis and endovascular treatments, have revolutionized stroke management and prognosis, providing a promising framework for exploring new therapeutic strategies. Endothelial dysfunction plays a critical role in the pathophysiology, progression, and prognosis of stroke.
View Article and Find Full Text PDFJ Clin Med
November 2024
Cardiology Department, Hospital Santa Creu i Sant Pau, Biomedical Research Institute (IIB Sant Pau), 08025 Barcelona, Spain.
Aortic stenosis is the most [...
View Article and Find Full Text PDFJ Clin Med
October 2024
Department of Nephrology, Fundació Puigvert, 08025 Barcelona, Spain.
J Nutr Health Aging
December 2024
Hospital del Mar Research Institute (IMIM), Carrer Doctor Aiguader 88, 08003 Barcelona, Spain; Blanquerna School of Health Sciences, Universitat Ramon Llull, Carrer Padilla 326, 08025 Barcelona, Spain; Consorcio Centro de Investigación Biomédica En Red (CIBER), M.P. Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Avenida Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, Spain. Electronic address:
Objectives: Not skipping breakfast is associated with a better overall diet quality and lower cardiometabolic risk. However, the impact of calorie intake and dietary quality of breakfast on cardiovascular health remains unexplored. We aimed to study the associations between breakfast energy intake and quality and time trajectories of cardiometabolic traits in high cardiovascular risk participants.
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