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SeDuS: segmental duplication simulator.
Bioinformatics
January 2016
Institute of Evolutionary Biology (Universitat Pompeu Fabra - CSIC), PRBB, 08003, National Institute for Bioinformatics, 08003, Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 and Centre for Genomic Regulation (CRG), 08003, Barcelona, Spain.
Summary: SeDuS is the first flexible and user-friendly forward-in-time simulator of patterns of molecular evolution within segmental duplications undergoing interlocus gene conversion and crossover. SeDuS introduces known features of interlocus gene conversion such as biased directionality and dependence on local sequence identity. Additionally, it includes aspects such as different selective pressures acting upon copy number and flexible crossover distributions.
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