N-terminal Backbone Pairing Shifts in CCL5-AAA Dimer Interface: Structural Significance of the FAY Sequence.

CC-type chemokine ligand 5 (CCL5) has been known to regulate immune responses by mediating the chemotaxis of leukocytes. Depending on the environment, CCL5 forms different orders of oligomers to interact with targets and create functional diversity. A recent CCL5 trimer structure revealed that the N-terminal conversed F12-A13-Y14 (FAY) sequence is involved in CCL5 aggregation.

Synthesis, Structural Characterization and Ligand-Enhanced Photo-Induced Color-Changing Behavior of Two Hydrogen-Bonded Ho(III)-Squarate Supramolecular Compounds.

Two coordination polymers (CPs) with chemical formulas, [Ho(CO)(CO)(HO)]·4HO (1) and [Ho(CO)(HO)] (2), (CO = dianion of squaric acid, CO = oxalate), have been synthesized and their structures were determined by single-crystal X-ray diffractometer (XRD). In compound , the coordination environment of Ho(III) ion is eight-coordinate bonded to eight oxygen atoms from two squarate, one oxalate ligands and four water molecules. The squarates and oxalates both act as bridging ligands with -bis-monodentate and -chelating coordination modes, respectively, connecting the Ho(III) ions to form a one-dimensional (1D) ladder-like framework.