Evaluation of Quality of Life and Psychosocial Status in Children with Inflammatory Bowel Disease.

Objectives: Inflammatory bowel disease (IBD) in children is a chronic condition that affects the psychosocial status and physical activities of children and their parents. This study aimed to investigate the impact of IBD on the quality of life of adolescents and their families and the variability of behavioral and emotional adjustment issues compared to a healthy control group.

Methods: This study was designed as a prospective controlled study.

Unusual Presentation of Acute Generalized Exanthematous Pustulosis with Unilateral Anterior Trunk Involvement.

Acute generalized exanthematous pustulosis (AGEP) is a rare drug eruption characterized by the rapid occurrence of many sterile, non-follicular pustules, neutrophilic leukocytosis, high fever and spontaneous resolution usually within two weeks. The distribution of rash predilection in the trunk and intertriginous regions. In treatment, the causative drug must be initially discontinued.

Drayer Syndrome due to Chromosome 15q26.3 Deletion: Response to Growth Hormone Treatment.

Chromosome 15q26 deletion is a rare condition that causes short stature and is associated with intrauterine growth restriction (IUGR), failure to thrive, congenital heart disease and many congenital malformations. The insulin growth factor receptor (IGF-1R) on chromosome 15 has many important roles, especially in growth regulation. Our case is an 18-month-old small for gestational age girl who presented with severe short stature, microcephaly and minor dysmorphic features.

The Association of Plasma Asymmetric Dimethylarginine Concentrations and Inflammation Markers in Non-small Cell Lung Cancer.

Objectives: Nonsmall cell lung cancer (NSCLC) accounts for about 85% of all lung cancers. Asymmetric dimethylarginine (ADMA) is an emerging molecule that is highlighted in carcinogenesis and tumor progression in lung cancer. Since elevated concentrations of ADMA are observed in lung cancer patients, we aimed to explore its associations with inflammation markers and established prognostic indices.

Endovascular Treatment in Symptomatic Intracranial Artery Stenosis: Experience from Two Centers.

Objectives: To assess the efficacy of endovascular treatment and clinical outcomes in individuals with symptomatic intracranial stenosis who had not responded adequately to medical intervention.

Methods: The study included 32 patients who received endovascular treatment due to high-grade (70%-99% severity) intracranial atherosclerotic stenosis from December 2021 to December 2023. The patients had not experienced any acute ischemic or hemorrhagic infarction within the last three weeks, had a Modified Rankin Scale score of ≤3 at baseline, and developed a transient ischemic attack or non-disabling stroke despite having received the best medical treatment.

The Role of Pre-operative "6 Minutes Walk Test" in Predicting the Risk of Early Pneumonia After Operation.

Objectives: The study's goal is to find out if there is a link between the results of the 6-minute walk test (6MWT) done before surgery and the chance of getting pneumonia after surgery in people with stage I lung cancer who are having a video-assisted thoracoscopic lobectomy.

Methods: We conducted a retrospective analysis on data from 194 patients with lung cancer who underwent VATS lung resection between January 2020 and August 2023. We assessed the preoperative 6MWT findings and the likelihood of developing postoperative pneumonia using a logistic regression model.

Surgical Management of Acute Appendicitis in a Patient with Diagnosed but "Unprepared" Pheochromocytoma: A Case Report.

Pheochromocytoma is a rare tumor originating from the adrenal gland, characterized by the secretion of catecholamines. Due to the risk of hypertensive crises associated with catecholamine release, surgical procedures in pheochromocytoma patients are risky. In this case report, laparoscopic appendectomy for acute appendicitis in a patient who has pheochromocytoma will be presented.

Mini-crush or Nano-crush Stenting Technique for Complex Coronary Bifurcation Lesions: The Multicenter MINANO Registry.

Background: This multicenter study aimed to retrospectively evaluate the mid-term clinical outcomes of mini-crush (MCT) and nano-crush (NCT) techniques in patients with complex bifurcation lesions (CBLs).

Methods: The study comprised 431 patients [male: 318 (73.8%), mean age: 60.

The effect of ultrasound-guided botulinum toxin injections on pain, functionality, spasticity, and range of motion in patients with post-stroke upper extremity spasticity.

Objective: Spasticity developing in the upper extremity in stroke patients causes disability by limiting movement and causing pain. This study investigates the effects of botulinum toxin injections on pain, functionality, spasticity, and range of motion in hemiplegic patients with post-stroke spasticity.

Materials And Methods: The study involved a double-blind, prospective, randomized controlled trial with thirty-one stroke patients aged 35-80 who developed upper extremity spasticity.

Effects of Rosmarinus officinalis extract on wound healing, colon anastomosis, and postoperative adhesion in colon anastomosis rats.

Background: Intraabdominal adhesions increase the incidence and length of surgical complications. Many anti-adhesive agents have been used for this purpose, but no definitive solution has yet been found. Studies on the prevention and reduction of anastomotic leakage, therefore, remain up to date.

External Auditory Canal Transillumination-Guided Middle Fossa Approaches: An Anatomical Feasibility Study.

Background And Objectives: The middle fossa approaches are tremendously versatile for treating small vestibular schwannomas, selected petroclival meningiomas, midbasilar trunk aneurysms, and lesions of the petrous bone. Our aim was to localize the internal acoustic canal and safely drill the petrous apex with these approaches. This study demonstrates a new method to locate the internal acoustic canal during surgery in the middle fossa.

Radiological Perspectives in Congenital Sensorineural Hearing Loss: Insights from Cochlear Implant Candidates.

Congenital hearing loss is a significant health concern, with diverse etiologies encompassing cochlear and cochleovestibular pathologies. Preoperative radiological evaluation in cochlear implant candidates is pivotal for treatment planning. We aim to elucidate the spectrum of radiological findings in patients with congenital hearing loss undergoing cochlear implant assessment.

Comparison of Smoking Cessation Outcomes in Smokers With Chronic Obstructive Pulmonary Disease, Coronary Artery Disease, Asthma, and Healthy Smokers: A Prospective Study of 400 Participants.

Objectives: In this study, we aimed to demonstrate the effect of motivational interviewing with a specific cohort of smokers on smoking cessation. Furthermore, we investigated the influence of medical conditions and individual traits on the efficacy of motivational interviewing for smoking cessation.

Methods: This prospective study was conducted with smokers who presented at the pulmonology and cardiology outpatient clinic.

Diagnosis, treatment, surgical practices and review of the literature in rare coagulation factor deficiencies.

Background: Rare bleeding disorders (RBDs) include fibrinogen (Factor I), prothrombin (Factor II), Factor V(FV), combined Factor V and Factor VIII, Factor VII, Factor X, Factor XI, Factor XII, and Factor XIII deficiencies. This group accounts for 3-5% of all factor deficiencies. Different symptoms may occur, ranging from mild or moderate bleeding to serious and life-threatening bleeding, which may not be related to the factor level.

Evaluating round window niche visibility in cochlear implantation: anatomical insights and electrode insertion strategies.

Purpose: Cochlear implantation (CI) surgery is essential for restoring hearing in individuals with severe sensorineural hearing loss. Accurate placement of the electrode within the cochlea is essential for successful auditory outcomes and minimizing complications. This study aims to analyze the relationship between the round window niche (RWN) alignment, its visibility during surgery, and the impact on surgical techniques and outcomes.

Comparison of the efficacy of treatment with clobetasol propionate or bexarotene in early-stage mycosis fungoides.

Background: There are few studies in the literature comparing the effectiveness of topical treatments in early-stage mycosis fungoides (MF).

Objectives: It was aimed to evaluate the clinical efficacy, side effects and topical treatment compliance with bexarotene or clobetasol propionate in early-stage MF.

Methods: A total of 40 patients with stage IA-IB MF were enrolled in the study.

Evaluating LLM-based generative AI tools in emergency triage: A comparative study of ChatGPT Plus, Copilot Pro, and triage nurses.

Background: The number of emergency department (ED) visits has been on steady increase globally. Artificial Intelligence (AI) technologies, including Large Language Model (LLMs)-based generative AI models, have shown promise in improving triage accuracy. This study evaluates the performance of ChatGPT and Copilot in triage at a high-volume urban hospital, hypothesizing that these tools can match trained physicians' accuracy and reduce human bias amidst ED crowding challenges.

Reality of Zuckerkandl tubercle and relationship with other anatomical variations.

Aim: The tubercle of Zuckerkandl (TZ) is considered to be the fusion point of the ultimabranchial body and the median thyroid body. We aimed to evaluate the frequency of TZ and its relationship with other anatomical variations and recurrent laryngeal nerve (RLN) paralysis.

Material And Methods: Data regarding the thyroid lobe and RLN of patients with thyroidectomy between June 2016 and December 2019 were retrospectively evaluated.

Can fecal calprotectin be used as a biomarker of non-alcoholic fatty liver disease in obese adolescents?

Background: The incidence of non-alcoholic fatty liver disease (NAFLD) is increasing with obesity, and it is believed that the ongoing low-grade inflammation in obesity and alterations in the enterohepatic axis contributing this process. This study aimed to determine the role of fecal calprotectin (FC) as inflammatory biomarker in obesity and NAFLD.

Methods: Between November 2022-August 2023, 31 obese and 10 healthy adolescents aged between 10 and 18 years enrolled in this prospective controlled study.

Factors Affecting Non-sentinel Lymph Node Metastasis in Early-Stage Breast Cancer.

Objective Breast cancer most commonly metastasizes to axillary lymph nodes via lymphatic drainage. Today, axillary lymph node surgery is at least as important as primary breast surgery. In today's breast surgery, supported by chemotherapy and radiotherapy, current approaches are taken to avoid axillary dissection in appropriate patient groups.

Acellular dermal matrices in reconstructive surgery; history, current implications and future perspectives for surgeons.

Large-scale defects of body in the reconstructive surgical practice, and the helplessness of their repair with autologous tissues, have been an important factor in the development of artificial biological products for the temporary, definitive, or staged repair of these defects. A major advance in the field of plastic and other reconstructive surgery in this regard has been the introduction and successful use of acellular dermal matrices (ADMs). In recent years, not only the type of tissue from which ADMs are produced, product range, diversity and areas of use have increased, but their use in reconstructive fields, especially in post oncologic breast surgery, has become highly regarded and this has favored ADMs to be a potential cornerstone in specific and well-defined surgical fields in future.

An appraisal and comparative analysis of superb microvascular imaging with conventional ultrasound and MRI for greater trochanteric pain syndrome management.

Greater trochanteric pain syndrome (GTPS) is a common cause of hip pain and is often associated with chronic lower back pain and lower extremity osteoarthritis. Its diagnosis is clinical; however, imaging has been shown to aid in the differential diagnosis of challenging cases. Superb microvascular imaging (SMI) is a new technique that may be more effective than power Doppler ultrasonography (PDUS) in the detection of inflammation-related vascularity in patients.