The efficacy and application of tranexamic acid in emergency medicine: Emergency Medicine Association of Türkiye clinical policy- 2024.

The clinical policy of the Emergency Medicine Association of Türkiye (EMAT) provides guidance on the use of tranexamic acid (TXA) in emergency settings. TXA, an antifibrinolytic drug, is used to control bleeding by inhibiting plasminogen. Its applications have expanded from hemophilia and severe menstrual bleeding to include various forms of trauma and surgery-related bleeding.

Predictors of Poor Outcomes in Chronic Obstructive Pulmonary Disease (COPD) Patients Admitted to the Emergency Department With COVID-19: A Prospective Study.

Objectives Long-term consequences of COVID-19 in the post-pandemic era are still being investigated. Despite the growing data on COVID-19, there remains a lack of information regarding predictors of poor outcomes among chronic obstructive pulmonary disease (COPD) patients with COVID-19.  Methods A single-center prospective cohort study was conducted with a total of 172 adult COPD patients with COVID-19 pneumonia included.

Hypoxia and Normoxia Preconditioned Olfactory Stem Cells Against Noise-Induced Hearing Loss.

Objective: Noise-induced hearing loss is one of the leading causes of permanent hearing loss in the adult population. In this experimental study, the authors aimed to investigate the effectiveness of hypoxia and normoxia preconditioned olfactory stem cells against noise trauma.

Methods: Twenty-seven female guinea pigs were enrolled.

Does dexamethasone therapy affect intimal hyperplasia after injury in rat abdominal aorta models?

Background: Intimal hyperplasia is a normal adaptive feature of arteries in response to injuries, which include invasive vascular interventions. Its development limits the long-term success of bypass grafts. Various pharmacological agents have been successfully employed in experimental models to reduce the degree of intimal hyperplasia.

Effect of hemolysis on D-dimer testing measured with the Improgen kit: is all manufacturer information correct?

D-dimer is a fibrin degradation product and its measurement is affected by hemolysis. This study was designed to reveal the value of hemolysis affecting D-dimer in our laboratory. In this study, hemolysate samples obtained by both mechanical and freezing methods were used.

Satisfaction of Patients and Their Relatives Who Are Reminded of Their Appointments and Treatments with "".

Background: Community Mental Health Centers have been established in Turkey for patients with chronic psychiatric disorders actively engaged in treatment. The Treatment Collaboration Portal is a web-based voice response platform offered to Community Mental Health Centres to support the treatment compliance processes of patients. The Treatment Collaboration Portal automatically reminds patients or their families of injection treatments and psychiatry appointments at regular intervals.

Videothoracoscopic First Rib Resection for Neurogenic Thoracic Outlet Syndrome: Results of 13 Patients.

Purpose: To present the clinical experience in video-assisted thoracic surgery (VATS) of first rib resection for patients with neurogenic thoracic outlet syndrome (NTOS).

Methods: The files of 13 patients (10 males, 3 females) having unilateral NTOS undergoing first rib resection via VATS were retrospectively investigated. The symptoms, operative times, durations of chest tube and hospital stay, complications, and postoperative courses were analyzed.

Clinical and demographic characteristics of late-onset multiple sclerosis: LOMS-TR study.

Objectives: Multiple sclerosis (MS), which is known as a young-adult age disease, is called late-onset MS (LOMS) when it occurs at the age of 50 and older. In our study, we aimed to analyse the clinical and demographic characteristics, comorbidities, diagnostic and treatment challenges and prognosis of LOMS.

Methods: In a retrospective analysis of 136 patients diagnosed with multiple sclerosis (MS) after the age of 50, based on the 2017 McDonald criteria, and who were under observation in eight distinct MS centers across Turkey; demographic information, clinical characteristics of the disease, oligoclonal band (OCB) status, initial and current Expanded Disability Status Scale (EDSS) values, administered treatments, and the existence of spinal lesions on magnetic resonance imaging (MRI) were investigated.

Are tube fill volumes below 90% a rejection criterion for all coagulation tests?

Background: Rejected samples lead to prolonged turnaround time and delayed diagnosis and treatment of patients. This study was conducted to determine minimum acceptable sample volume in Sarstedt brand coagulation tubes to reduce high sample rejection rate.

Methods: Blood samples were drawn from 20 participants (10 healthy volunteers and 10 patients receiving oral anticoagulant) into coagulation tubes.

Childhood Trauma as an Environmental Determinant of Risk of Violence in Bipolar Disorder.

Introduction: The complex interaction of violent behavior, childhood trauma and bipolar disorder (BD) is unclear. Therefore, we aimed to investigate the risk factors of violence in BD and studied the relationship between different types of childhood trauma and violence.

Methods: We assessed 105 remitted patients diagnosed with BD I (n=91) or BD II (n=14).

Clinical Features of Women with Genito-Pelvic Pain, Penetration Disorder and Disordered Eating Attitudes: A Cross Sectional Study.

Introduction: Current studies indicate a strong relationship between sexual dysfunctions and eating disorders. The aims of this study were to investigate the frequency of disordered eating behaviors (DE) in patients with genito-pelvic pain and penetration disorder (GPPPD); and to determine the clinical features associated with DE.

Methods: Outpatients with GPPPD (n=105) were evaluated with sociodemographic data form, structured clinical interview for DSM-IV (SCID), Golombok-Rust inventory of sexual satisfaction female form (GRISS), Hamilton anxiety rating scale (HAM-A), Hamilton depression rating scale (HAM-D), eating disorder examination questionnaire (EDEQ), and eating attitudes test (EAT-40).

Accuracy of Different Lens Power Calculation Formulas in Patients With Mature Cataracts.

Introduction To compare the prediction accuracy of lens power calculation formulas in patients undergoing mature cataract surgery. Methods A total of 90 operations involving the Alcon SA60AT IOL implant (Alcon, Geneva, Switzerland) were analyzed in terms of mean refractive prediction error (PE) and mean absolute prediction error (MAE) using backward calculation in a retrospective design. Results A negative PE was observed in SRK/T, Holladay 1, Holladay 2, Hoffer Q, Haigis, and Emmetropia Verifying Optical (EVO) formulas.

The role of calcitonin gene-related peptide and substance P in the pathogenesis of dialysis headache.

Aim: The present study aims to establish the role of serum CGRP and SP levels in the disease pathophysiology in patients with dialysis headache not accompanied by primary or secondary headaches, and also whether there is a correlation between these vasoactive peptides and the severity of headache.

Method: This study was designed as prospective and multicenter. A total of 30 dialysis headache patients and 30 patients without headache as the control group in the Nephrology outpatient clinics which implement similar dialysis procedures were included in the study.

Non-invasive assessment of the tear film after LASIK.

Objective: The aim of the study was to compare the assessment of the ocular surface using classic methods with the newly developed keratoscopy-based MYAH (Topcon EU, Visia Imaging, Japan) device after femtosecond laser-assisted in situ keratomileusis (LASIK).

Patients And Methods: This cross-sectional and observational study analyzed 80 eyes of 40 patients. Tear film and ocular surface evaluation were performed at baseline, postoperative week 1, and month 1.

Effectiveness of Lactate Clearance to Predict In-Hospital Mortality in Patients with Upper Gastrointestinal Bleeding.

Objective: To determine the performance of lactate clearance to predict prognosis in patients with upper gastrointestinal bleeding (UGIB).

Study Design: Observational study. Place and Duration of the Study: Department of Emergency Medicine, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey, from January 2018 to 2022.

Frequency And Factors Associated With Adverse Reactions After Administration of Inactivated COVID-19 Vaccine Among Health Workers.

Background: The 2019 coronavirus (COVID-19) has precipitated a significant public health crisis. Our study aimed to evaluate the prevalence and risk factors associated with adverse reactions to the inactivated CoronaVac vaccine.

Methods: The study involved voluntary health workers who received CoronaVac vaccine.

Deformity correction and limb lengthening with externally controlled motorized extendable intramedullary nails: Comparison of 2 different nails.

Objective: The aim of this study was to assess and compare the clinical, radiological, and functional results of patients treated with FITBONE or PRECICE nails due to deformity and length discrepancy in their lower extremities.

Methods: This retrospective cohort study included 41 patients with length discrepancy and deformity in their lower extremities, who underwent limb lengthening surgery with either FITBONE (group F) or PRECICE (group P) nails between 2010 and 2020. The mean postoperative follow-up period was 15.

The effects of measures taken during the COVID-19 pandemic on the seasonal dynamics of respiratory viruses in children.

Background: We aimed to evaluate the effects of public health measures taken during the COVID-19 pandemic on respiratory viruses.

Methods: The study was conducted between February 1, 2021 and December 1, 2022. Patients aged 1 month to 18 years hospitalized for infectious diseases were tested for SARS-CoV-2 and respiratory viruses by multiplex PCR.

Conservative Approach For The Management Of Bilateral Pneumothorax And Pneumomediastinum After Laparoscopic Totally Extraperitoneal Inguinal Hernia Repair.

Laparoscopic totally extraperitoneal inguinal hernia repair is considered a common and safe procedure. Here, we present the case of a 31-year-old male with right indirect inguinal hernia and no medical history. The patient underwent laparoscopic totally extraperitoneal inguinal hernia repair and the operation was completed successfully.