112 results match your criteria: "İzmir Katip Çelebi University Medical Faculty[Affiliation]"

Cardiomyopathy, which is shortly defined as a disease of the myocardium, has a broad definition that includes many different diagnoses. Recent advances in cardiac imaging techniques, including basic and advanced echocardiography, computed tomography, nuclear medicine, and cardiac magnetic resonance, allow for a more accurate evaluation of volumes and thickness of cardiac chambers, systolic and diastolic function of the ventricules, and tissue structure. Multimodality imaging often provides the first clinical suspicion for specific etiologies, especially when the medical and family history is unclear, by identification of red flags of underlying systemic diseases.

View Article and Find Full Text PDF

: Secukinumab is a monoclonal antibody against interleukin 17 approved for patients with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), and psoriasis. Treating axSpA and PsA patients with a history of malignancy is a challenge. While initial results on the applicability of secukinumab in this patient group are positive, the number of studies on this topic remains limited.

View Article and Find Full Text PDF

Objective: To evaluate the etiology-specific diagnosis of early-onset developmental epileptic encephalopathies (EO-DEEs) in a nationwide Turkish cohort to determine the implications for therapeutic management.

Methods: The cohort comprised 1450 patients who underwent EO-DEE. The utility of genetic testing was assessed with respect to the initial phases of next generation sequencing (NGS) (2005-2013) and the current NGS era (2014-2022).

View Article and Find Full Text PDF

Purpose: To evaluate limbal graft transplantation success in pediatric patients with chemical injury-induced limbal stem cell deficiency (LSCD) using the 'LSCD Working Group' staging system.

Methods: Medical records of 11 eyes of 11 children who underwent limbal graft transplantation (limbal autograft/limbal allograft) were included. Surgical success was defined as improvement in the post-operative 1st year LSCD stage.

View Article and Find Full Text PDF

Background: Acute respiratory failure is a prevalent condition in childhood with a high rate of mortality. Invasive mechanical ventilation support may be required for the management of these patients. Extracorporeal membrane oxygenation (ECMO) is a method used when ventilation support is insufficient.

View Article and Find Full Text PDF
Article Synopsis
  • Colorectal cancer is a major global health issue, and in Turkey, a study was conducted to assess the effectiveness of second-line treatments for patients with RAS wild-type metastatic colorectal cancer.
  • The research involved a retrospective analysis of 588 patient records from 28 centers, categorizing them by the type of biological treatments received: anti-EGFR and anti-VEGF.
  • Results showed no significant differences in overall survival or progression-free survival among the different treatment groups, indicating similar effectiveness of the biological agents in second-line treatments.
View Article and Find Full Text PDF

A Different Method to Increase Breast Projection-Tunnelized Glandular Flap.

Aesthetic Plast Surg

October 2024

Department of Plastic, Reconstructive and Aesthetic Surgery, Izmir Katip Celebi University Medical Faculty, Izmir Katip Celebi University, Basın Sitesi, Karabağlar, 35360, İzmir, Turkey.

Background: Breast ptosis may occur with increasing age, after pregnancy, after breastfeeding, or after weight loss. Understanding the vascular structure of the breast and nipple-areolar complex has guided the reshaping of the breast and thus paved the way for the emergence of different techniques. This study aimed to evaluate the results of tunneled glandular flaps used to increase projection in patients undergoing breast lift surgery.

View Article and Find Full Text PDF

Background: Protruding ears are the most common auricular abnormalities seen in children (1). Protruding ears are a condition that has social and psychological consequences due to its physical appearance and one of the main causes of peer bullying at young ages (2). While various surgical methods exist to address prominent ears, the options for correcting the lobule are relatively scarce.

View Article and Find Full Text PDF

Background: Cognitive evaluation was considered to be very important in the relapse period, on the basis of the presence of isolated cognitive attacks and the necessity of monitoring the patient both physically and cognitively.

Materials And Methods: People with MS (pwMS) who were hospitalized during relapse were included in the study. All MS patients were evaluated by the neurologist with Expanded Disability Status Scale (EDSS), The 9 Hole Peg Test (9HPT) and the Timed 25-Foot Walk Test (T25-FWT).

View Article and Find Full Text PDF
Article Synopsis
  • C3 glomerulopathy (C3G) is a kidney disease influenced by genetic factors, and this study explores the differences in clinical outcomes among pediatric patients with and without mutations in complement-related genes.
  • Among 60 patients studied, 17 had genetic mutations with the CFH gene being the most common; those with mutations typically showed asymptomatic urinary issues and were diagnosed at an older age.
  • Despite differences in presentation, both groups had similar long-term kidney survival and response to mycophenolate mofetil treatment, indicating that genetic mutations may not significantly impact treatment outcomes.
View Article and Find Full Text PDF

Objective: Studies have shown that theory of mind, emotion regulation and pragmatic abilities are negatively affected in people with obsessive-compulsive disorder OCD). We aimed to investigate theory of mind (ToM) abilities, social responsiveness, pragmatic language, and emotion regulation skills in children with OCD and to compare them to healthy controls.

Methods: This study was designed as a single-center, cross-sectional, case-control study.

View Article and Find Full Text PDF

The prognostic significance of tumor volume (TV) in laryngeal squamous cell cancer (LSCC) has been demonstrated previously. Still, its clinical use is uncertain, and a method for accurate staging for TV is lacking. This study aimed to develop an objective staging and determine the effect of tumor volume on disease outcome after surgical treatment for LSCC.

View Article and Find Full Text PDF

Objectives: Lipohemarthrosis is a key finding in acute trauma patients and indicates an intra-articular fracture. The horizontal beam lateral radiography with supine position is known to be the best technique to demonstrate knee lipohemarthrosis. Our main purpose was to compare the sensitivity of supine and standing lateral knee radiographs to detect lipohemarthrosis.

View Article and Find Full Text PDF

Introduction: Peripheral perfusion index has been proposed as a possible method for detecting circulatory impairment. We aimed to determine the normal range of peripheral perfusion index in healthy newborns and compare it with that of newborns with CHD.

Methods: Right-hand saturation and right-hand peripheral perfusion index levels were recorded, and physical examination and echocardiography were performed in newborns who were 0-28 days old and whom were evaluated in our paediatric cardiology outpatient clinic.

View Article and Find Full Text PDF

Introduction:  Coexistent congenital duodenal obstruction and esophageal atresia (EA) is known to have significant morbidity and mortality. Management strategies are not well-defined for this association. The data from the Turkish EA registry is evaluated.

View Article and Find Full Text PDF

Nasal Sill Flap for Lip Lifting.

Facial Plast Surg

February 2024

Private Practice, Kultur Mah. Sair Esref Bul. No:61 Bahar Apartmanı K:2 D:5 Alsancak/Izmir, Turkey.

Background:  Over the years, different techniques have been developed to reduce the number of incisions and scars in subnasal lip lifting and to increase the amount of lifting. The aim of this study was to present a new technique to hide the scars at the nasal base in subnasal lip lifting procedures and to review the literature.

Methods:  The file of patients who underwent subnasal lip lifting between January 2019 and January 2021 were examined.

View Article and Find Full Text PDF

In this multi-centre study, the mid- to long-term efficacy and safety of the Amplatzer Piccolo Occluder in patent ductus arteriosus closure in premature and term infants as well as children were discussed. Methods. Between 2016 and 2021, 645 patients, 152 of whom were less than 1 month old, underwent ductus closure with the Piccolo device from five different centres in Turkey.

View Article and Find Full Text PDF

Glutaric aciduria and L-2-hydroxyglutaric aciduria: Clinical and molecular findings of 35 patients from Turkey.

Mol Genet Metab Rep

September 2023

Izmir Katip Celebi University, Tepecik Research and Training Hospital, Department of Pediatrics, Division of Pediatric Metabolism, Izmir, Turkey.

Background: Cerebral organic acid disorders are progressive neurometabolic diseases characterized by neurologic dysfunction. Glutaric aciduria type I (GA-I) and L-2-hydroxyglutaric aciduria (L2HGA) are the main cerebral organic acid disorders. They are both classified as, and it is suggested that these two disorders may share a common metabolic pathway.

View Article and Find Full Text PDF

The effect of botulinum neurotoxin A on soft-tissue complications in intraoral reconstructions.

J Plast Reconstr Aesthet Surg

April 2023

Izmir Katip Celebi University Medical Faculty, Department of Plastic, Reconstructive and Aesthetic Surgery, Izmir, Turkey.

Background: Intraoral reconstruction has become more common in recent years. Patients may suffer from complications because of hypersalivation. This issue can be overcome with an aid aimed at reducing saliva production.

View Article and Find Full Text PDF

Background: Stroke, the most feared complication in patients with atrial fibrillation (AF), is still an important cause of mortality and morbidity. In our study, we aimed to investigate the frequency of stroke and related parameters in patients with atrial fibrillation, for whom 24-h ambulatory blood pressure monitoring (ABPM) was performed.

Method: A total of 282 patients with permanent AF were included in this study.

View Article and Find Full Text PDF

Background:  Periorbital fractures are a condition encountered after high-energy trauma in the face region. In the follow-ups after surgical repair, some changes may occur in the lower eyelid. Scleral show, ectropion, entropion, and canthal malposition are the most common complications.

View Article and Find Full Text PDF

Objectives: Adult-onset Still's disease (AOSD) is a multi-systemic, autoinflammatory disorder. Several activity scores have been proposed but none of them have been adopted universally. Our aim was to create a clinician-friendly activity scoring system by using simple clinical and laboratory parameters.

View Article and Find Full Text PDF