Correlation of Histopathological and Radiological Response Patterns and Their Prognostic Implications in Breast Cancer After Neoadjuvant Chemotherapy.

Purpose: In breast cancer (BC), neoadjuvant chemotherapy (NAC) responses can be categorized as concentric shrinkage (CS), non-concentric shrinkage (non-CS), and complete response, influencing surgical planning and survival. This study evaluates the correlation between histopathological and radiological response patterns in BC patients after NAC and their impact on overall survival (OS) and disease-free survival (DFS).

Patients And Methods: This retrospective study analyzed 168 BC patients who received NAC between 2018 and 2022.

Comparison of glaucoma progression rate in glaucoma patients at different stages using guided progression analysis with optical coherence tomography.

Background: The aim of the present study was to compare the rates of change in Ganglion Cell- Inner Plexiform Layer (GCIPL) and Retinal Nerve Fiber Layer (RNFL) thickness, as measured by Optical Coherence Tomography (OCT) Guided Progression Analysis (GPA) program in control group, Primary Open Angle Glaucoma (POAG) and Pseudoexfoliation Glaucoma (PXG) eyes.

Methods: 60 POAG and 60 PXG patients and 30 control group patients were included in the study. Patients diagnosed with glaucoma were divided into two groups as mild (Mean deviation (MD) > -6.

Comparison of the Cone Beam Computed Tomography-Based Analysis of the Masseter Muscle Between Epilepsy Patients and Healthy Subjects.

It is important to investigate the changes in the masseter muscle, one of the chewing muscles, in epilepsy patients and to determine whether epilepsy can be effectively predicted on muscle. The aim of this study is to measure masseter muscle thickness, circumference and cross-sectional area in individuals with epilepsy and healthy individuals. This study was performed with 128 individuals (64 epilepsy patients and 64 healthy subjects) aged between 18 to 59 years.

Temporomandibular joint and masticatory muscles morphometry and morphology in healthy subjects and individuals with temporomandibular dysfunction: An anatomical, radiological, and machine learning application study.

The study aimed to compare the morphometric and morphologic analyses of the bone structures of temporomandibular joint and masticatory muscles on Cone beam computed tomography (CBCT) in 62 healthy subjects and 33 subjects with temporomandibular dysfunction (TMDS) aged between 18 and 56 years. In addition, a machine learning (ML) pipeline involving the Random Forest classifier was used to automatically detect TMDS. Thirty parameters (including age and gender) associated with the condylar process, articular tubercle, mandibular fossa, ramus mandible, joint space, and masticatory muscles were examined using CBCT.

Validity and Reliability of the Turkish Version of the Medial Tibial Stress Syndrome Score.

Background: Medial tibial stress syndrome (MTSS) is a common leg injury in military personnel and athletes and is especially related to running and jumping. A patient-reported outcome measure, the MTSS score, was developed to determine the severity of MTSS.

Purpose: To translate, culturally adapt, and validate the MTSS score for the Turkish language.

Rib fracture characteristics increasing the risk of hemothorax: a multicenter study.

The precise assessment of hemothorax risk resulting from a rib fracture is not feasible. CT images, patient characteristics, and clinical experience are utilized in daily practice to assess risk intuitively. This study aimed to identify specific markers on CT images that can predict the risk of hemothorax.

Relationship of Serum Microsomal Prostaglandin E2 Levels with Residual Tumor Volume in Patients with Astrocytoma.

Aim: To investigate the relationship between tumor volume and serum microsomal prostaglandin E2 (mPGE2) levels in patients with astrocytic tumors.

Material And Methods: The study included patients with astrocytic tumors who were treated at our clinic between August 2015 and December 2016. Preoperative and postoperative contrast-enhanced cranial magnetic resonance imaging (MRI) scans were performed (within the first 24 h), and preoperative and postoperative residual tumor volumes were calculated.

Late corneal ectasia after penetrating and deep anterior lamellar keratoplasty for keratoconus.

Aim: To investigate tomographic features of late corneal ectasia after keratoplasty for keratoconus and compare penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) in terms of incidence, time of onset and risk factors of corneal ectasia.

Methods: Sixty eyes with PK and 30 eyes with DALK operated between 1999 and 2021 were analyzed. Final Pentacam scans were evaluated together with vision and previous topographies.

Evaluation of Clinical Effects of COVID-19 Infection and Vaccines on Myasthenia Gravis.

Introduction: In this study, we aimed to investigate the clinical effects of COVID-19 infection and vaccines on Myasthenia gravis (MG) during the pandemic.

Methods: A total of 141 MG patients between April 2020 and December 2021 were retrospectively analyzed. Data including demographic and clinical characteristics of patients, COVID-19 test results, and vaccine types (mRNA-BNT162b2 and/or inactivated-CoronaVac) were recorded.

Comparison of Conventional Technique with Suture Fixation and Subperiosteal Tight Pocket Technique on Revision Cochlear Implantation Rate.

Several fixation methods have been described to secure the cochlear implant's receiver/stimulator, but the optimal stabilization technique is still being debated. The aim of this study was to compare the conventional technique with suture fixation to the subperiosteal tight pocket technique in terms of revision cochlear implantation rate. A retrospective review was conducted on the medical records of 649 patients who underwent cochlear implantation.

Potential difficult-to-treat psoriatic arthritis real-world prevalence and contributing factors.

Objectives: The challenge of achieving low disease activity or remission in psoriatic arthritis (PsA) is an unmet need for many patients. Persistent disease activity in PsA may require treatment adjustments due to its complex pathogenesis and varied tissue involvement, highlighting the need for dedicated definitions. This study evaluates patients' frequency and contributing factors with potential "difficult-to-treat PsA (D2TPsA)", similar to the EULAR definition of D2T rheumatoid arthritis.

Evaluation of menstrual irregularities following COVID-19 infection or vaccination: The impact of COVID anxiety and associated risk factors.

There has been significant interest in the changes in menstrual cycles following coronavirus disease 2019 (COVID-19) infection or vaccination. This study aimed to investigate the evidence for such changes and their potential risk factors. We used a descriptive study design and gathered data by sharing an online survey questionnaire on social media platforms.

Surgical Technique for Draining a Concomitant Supra-and Infratentorial Epidural Hematomas.

Aim: To assess clinical and radiological characteristics of simultaneous acute supra- and infratentorial epidural hematomas.

Material And Methods: We retrospectively reviewed the clinical and radiological data of 18 patients with a concomitant acute supra- and infratentorial epidural hematoma, who were treated and followed up at our hospital.

Results: The Glasgow Coma Score was 3-8 in four patients, was 9-12 in seven, and was 13-15 in seven patients.

Does having a family member with dementia affect health beliefs about changing lifestyle and health behaviour for dementia risk reduction?

Background: Dementia is a worldwide public health concern. Implementing lifestyle changes that target modifiable risk factors is crucial for reducing the risk of dementia. The aim of this study was to investigate the effect of having family members with dementia on individuals' health beliefs and tendencies towards adopting healthier lifestyles and behaviours.

Comparison of the Outcomes of Anterior Cervical Discectomy and Fusion and Cervical Disc Replacement for Cervical Disc Disease.

Objective: To compare the radiological outcome and development of heterotopic ossification (HO) following single-segment anterior cervical discectomy and fusion (ACDF) and cervical disc replacement (CDR) for cervical disc herniation and evaluate their impact on surgical success.

Study Design: Descriptive comparative study. Place and Duration of the Study: Neurosurgery Department at Bozyaka Education and Research Hospital, Izmir, Turkiye, between January 2020 and June 2022.

Managing Severe Postburn Wrist Flexion Contracture by Proximal Row Carpectomy and Abdominal Interpolation Flap.

Postburn upper extremity contractures can greatly diminish the quality of life. To successfully manage these contractures and achieve successful functional outcomes, an optimal surgical method should be planned to address all affected tissues on the extremities. Conventional soft tissue transfers after releasing the contracture, such as skin grafts or flaps, may be insufficient.

Surgical smoke: a matter of hygiene, toxicology, and occupational health.

The use of devices for tissue dissection and hemostasis during surgery is almost unavoidable. Electrically powered devices such as electrocautery, ultrasonic and laser units produce surgical smoke containing more than a thousand different products of combustion. These include large amounts of carcinogenic, mutagenic and potentially teratogenic noxae.

Immunosuppressive treatment results in patients with primary IgA nephropathy in Turkiye; the data from TSN-GOLD working group.

Background: Immunoglobulin A (IgA) nephropathy (IgAN) treatment consists of maximal supportive care and, for high-risk individuals, immunosuppressive treatment (IST). There are conflicting results regarding IST. Therefore, we aimed to investigate IST results among IgAN patients in Turkiye.

Assessing the quality and reliability of YouTube videos as a source of information on inflammatory back pain.

Background: Inflammatory back pain is a chronic condition with localized pain, particularly in the axial spine and sacroiliac joints, that is associated with morning stiffness and improves with exercise. YouTube is the second most frequently used social media platform for accessing health information. This study sought to investigate the quality and reliability of YouTube videos on inflammatory back pain (IBP).

Perineural 5% dextrose versus corticosteroid injection in non-surgical carpal tunnel syndrom treatment.

Background And Purpose:

A new femur intramedullary nail with tube and coil spring for maximum interfragmentary rotational and axial stability after fracture site resorption.

Objective: This study aimed to biomechanically compare the maximum rotational, axial movements, and compression forces between fracture fragments before and after 1-4 mm fracture site resorption among interlocking nails, compression nails, and newly designed compressive anti-resorption (CARES) nails compressed with tube and coil spring.

Methods: We determined the maximum axial/rotational movements and interfragmentary compression loads between fragments on 10 interlocking nails, 10 compression nails, and 10 CARES nails with 30 composite femurs. Using a compression-distraction testing device, 6 N·m external and internal torques were applied, and we evaluated the maximum rotational and axial displacement between fragments after 1-4 mm fracture site resorption.

Hepatobiliary-Specific MRI Contrast Agent Detection of Subvesical Duct (Luschka's) Injury Post-Laparoscopic Cholecystectomy: A Case Report.

Post-laparoscopic cholecystectomy bile duct injuries, especially involving Luschka's duct, are concerning. Biliary tree anomalies and the efficacy of intravenous administration of Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) in detecting bile leakage are reported based on a case. Hepatobiliary-specific MRI-contrast agents prove valuable for noninvasive assessment of bile leakage after cholecystectomy.

A Rare Reason for Severe Hypocalcemia Following Kidney Transplant: Denosumab Treatment.

Deviations of calcium, phosphate, parathyroid hormone, and vitamin D levels are the basis for the diagnosis of calcium-phosphate metabolism disorders. The plasma concentration of the biologically active form known as free calcium is regulated in a harmonious manner by its exchange in the bones and reabsorption by the kidneys. These steps take place under the control of parathyroid hormone and calcitriol.

Relationship of Serum Kallistatin Level With Arterial Stiffness and Metabolic Parameters in Obesity-Related Chronic Kidney Disease.

Objectives: We investigated the relationship between serum kallistatin and kidney disease and proteinuria in nondiabetic obesity-related chronic kidney disease and observed the effects on arterial stiffness.

Materials And Methods: We included 40 patients with nondiabetic obesity-related chronic kidney disease followed in our nephrology clinic and a control group of 40 participants without chronic kidney disease matched by age, sex, and mean body mass index (measured as weight in kilograms divided by height in meters squared). Pulse-wave velocity and augmentation index were measured oscillometrically by pulse-wave analysis (Mobil-O-Graph) by the same operator.