1 results match your criteria: "İstanbul Technical University Faculty of Chemical-Metallurgical Engineering[Affiliation]"
Preparation and Characterization of the Release Behavior of PVA: Na-Alg Microsphere Containing Fampridine.
Turk J Pharm Sci
January 2025
İstanbul Technical University Faculty of Chemical-Metallurgical Engineering, Department of Chemical Engineering, İstanbul, Türkiye.
Objectives: This study focuses on both the formulation of bio-based microspheres containing fampridine for the treatment of multiple sclerosis and provides an alternative to the commercially available product (Fampyra 10 mg, Biogen).
Materials And Methods: The encapsulation of fampridine was achieved using polyvinyl alcohol (PVA) and sodium alginate (Na-Alg) polymers. Glutaraldehyde (GA) and hydrochloric acid (HCI) were used as crosslinking agents.