933 results match your criteria: "İstanbul Kanuni Sultan Süleyman Training and Research Hospital[Affiliation]"

Laparoscopic sleeve gastrectomy is a restrictive surgery that aims to decrease the gastric volume of the patient. This study hypothesized that a higher resected gastric volume to the number of fired staplers ratio is associated with improved postoperative 12th-month outcomes. To analyze the effects of resected gastric volume to the number of fired staplers ratio on postoperative results in patients who underwent sleeve gastrectomy.

View Article and Find Full Text PDF

Introduction: The severity of electrical injuries depends on the voltage, the duration of exposure to current, and the trajectory of the current through the body. The reconstruction for defects caused by electric current is a difficult process.

Objective: The purpose of this study is to investigate the effectiveness of the reverse first dorsal metatarsal artery (FDMA) flap in the reconstruction of distal foot injuries caused by electric currents.

View Article and Find Full Text PDF

Preseptal cellulitis is a commonly observed inflammation of the eyelid and the surrounding skin in pediatric patients, especially after a minor trauma. Although preseptal cellulitis is generally associated with a more favorable prognosis, it is vital to remember that all orbital infections require prompt diagnosis and treatment because of the risk of severe complications. Inadequate or failure to adhere to the treatment plan and unmet hygiene standards can lead to severe complications; therefore, diligent follow-up care should be undertaken by both the physician and the patient.

View Article and Find Full Text PDF

Introduction: Intravenous immunoglobulin (IVIG) is an alternative for post-exposure prophylaxis if a vaccine is contraindicated and intramuscular immunoglobulin is unavailable. We retrospectively examined the effect of IVIG administration time on measles development in measles-contact infants younger than 6 months of age.

Methodology: Contact tracing of measles cases was performed by the Istanbul Public Health Directorate (IPHD) between August 24, 2012, and June 16, 2013.

View Article and Find Full Text PDF

Purpose: Postoperative pain is an acute pain that begins with surgical trauma and decreases as the tissue heals. The transversus abdominis plane (TAP) block is one of the abdominal field blocks used in the treatment of acute postoperative pain after lower abdominal surgery. This study aims to investigate the effects of dexamethasone added to a local anesthetic solution on postoperative analgesia in ultrasonography-guided TAP block.

View Article and Find Full Text PDF

Lactate is a product of anaerobic metabolism used to determine prognosis in critically ill trauma patients. This study investigates the mortality-predictive performance of lactate, lactate clearance, and lactate-to-albumin ratio (LAR) on admission in patients with polytrauma in a tertiary center's intensive care unit (ICU). Polytrauma patients in the ICU between June 2019 and June 2022 were evaluated.

View Article and Find Full Text PDF

Objective: In our study, we attempted to determine the accreditation process experience of hospital senior managers accredited by the Turkish Health Care Quality and Accreditation Institute (TUSKA). Along with the institutions' accomplishments through the accreditation program, the major challenges they faced during the accreditation process were revealed.

Methods: One of the qualitative research designs used was interpretive phenomenological analysis, which was carried out through semi-structured interviews with hospital senior managers.

View Article and Find Full Text PDF

Convolutional Neural Networks in the Diagnosis of Cervical Myelopathy.

Rev Bras Ortop (Sao Paulo)

October 2024

Departamento de Ortopedia e Traumatologia, Istanbul Faculty of Medicine, Istanbul University, Istambul, Turquia.

 Artificial intelligence technologies have been used increasingly in spine surgery as a diagnostic tool. The aim of the present study was to evaluate the effectiveness of the convolutional neural networks in the diagnosis of cervical myelopathy (CM) compared with conventional cervical magnetic resonance imaging (MRI).  This was a cross-sectional descriptive analytical study.

View Article and Find Full Text PDF

Referrals to emergency services are frequently made for acute appendicitis and renal colic. This conundrum of patients with acute appendicitis and right ureteral stones frequently presents itself to emergency physicians. The hematological parameters of patients suffering from acute appendicitis and right ureteral stones were compared in this study.

View Article and Find Full Text PDF

Dysfunction of PTEN-Associated MicroRNA Regulation: Exploring Potential Pathological Links in Type 1 Diabetes Mellitus.

Medicina (Kaunas)

October 2024

Department of Internal Medicine, Kanuni Sultan Suleyman Training and Research Hospital, Health Sciences University, Istanbul 34668, Türkiye.

Type 1 Diabetes Mellitus (T1DM) is an autoimmune disease with T cell-mediated pathogenesis of pancreatic β-cell destruction, leading to insulin deficiency. MicroRNAs such as miR-223 and miR-106b, along with PTEN, have been reported to participate in the pathophysiology of diabetes and its complications. The current study has explored the expression of miR-223, miR-106b, and PTEN and their association with various clinical and biochemical parameters in subjects diagnosed with T1DM.

View Article and Find Full Text PDF

Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options.

Res Pract Thromb Haemost

October 2024

Department of Internal Medicine, Division of Hematology, Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.

Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

View Article and Find Full Text PDF
Article Synopsis
  • Anaphylaxis is a life-threatening allergic reaction, and understanding its triggers is crucial for preventing severe cases known as refractory anaphylaxis (RA).
  • A study analyzed data from 1,378 patients diagnosed with anaphylaxis, finding that 3.3% had RA, with a history of anaphylaxis being the strongest risk factor.
  • Other factors such as the use of beta-blockers/ACE inhibitors, exposure to IV contrast agents, and symptoms of low blood pressure were also linked to increased severity, highlighting the need for prompt treatment to improve patient outcomes.
View Article and Find Full Text PDF

Objective: This study was conducted to determine the relationship between bone mineral density, vitamin D level, and sleep quality in female patients with osteoporosis.

Methods: This descriptive correlational study included a total of 318 women diagnosed with osteoporosis. The data were collected using a patient identification form, including items for the plasma vitamin D level and bone mineral density score obtained by the dual-energy X-ray absorptiometry method, and the Pittsburgh Sleep Quality Index.

View Article and Find Full Text PDF
Article Synopsis
  • Stigma in multiple sclerosis (MS) leads to negative outcomes such as anxiety, depression, and social isolation, although there's currently no specific scale to measure it.
  • The study aimed to create and validate a "Multiple Sclerosis Stigma Scale (MSSS)" through a three-phase methodological approach, which included defining stigma, generating items, and testing the scale's psychometric properties.
  • The final 12-item MSSS showed strong reliability and validity in assessing stigma, revealing two main factors: discrimination and disclosure, making it suitable for use with Turkish MS patients.
View Article and Find Full Text PDF

: The aim of this study was to investigate the circulating levels of asprosin, clusterin, zinc-alpha-2-glycoprotein (ZAG), nuclear factor-kappa B (NF-κB), and peroxisome proliferator-activated receptor-gamma (PPAR-γ) in patients with T2DM in relation to microvascular and macrovascular complications. Measuring these biomarkers may provide insight into the pathophysiology of T2DM and indicate novel targets for the therapy of diabetes-related complications. : A total of 260 subjects consisting of four groups: healthy controls (Group-1), T2DM patients without complications (Group-2), T2DM patients with microvascular complications (Group-3), and T2DM patients with macrovascular complications (Group-4).

View Article and Find Full Text PDF

The First Surgery Experienced Through Virtual Reality: A Knee Surgery Case Report.

J Perianesth Nurs

October 2024

Surgical Medical Sciences, Department of Anesthesiology and Reanimation, Karadeniz Technical University, Trabzon, Turkey.

The decision to undergo surgery and the significance of the operating theater environment are influenced by several factors, which vary from person to person. Negative perceptions of the operating room environment can influence the decision to undergo surgery and the process of treatment. Virtual reality (VR) technology offers the potential to alter individuals' environmental encounters through the provision of diverse environmental perceptions.

View Article and Find Full Text PDF
Article Synopsis
  • * It found that the RSV only group had lower pH and higher rates of bronchiolitis, while the RSV with viral agents group experienced longer hospital stays and more severe symptoms.
  • * Additionally, cases with bacterial co-infections were generally younger and had different clinical markers, highlighting that combined viral and bacterial infections can worsen RSV severity and impact treatment approaches like High Flow Nasal Cannula-Oxygen Therapy.
View Article and Find Full Text PDF

Hepatitis C virus (HCV) is a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma worldwide. HCV has 8 genotypes (GT) and 86 subtypes and distribution of GTs varies based on geographical regions, transmission routes and even in cultural groups. The determination of viral genotype is crucial in choosing antiviral treatment, determining the duration of therapy, and monitoring treatment respose.

View Article and Find Full Text PDF

Background:  Obesity has become a global health crisis in adults, and is linked to conditions like diabetes, cardiovascular diseases, and cancer. This study explored associations between body mass index (BMI) and laboratory parameters in healthy individuals to identify risk factors and guide targeted interventions in Turkey. It was found that screening and lifestyle changes can help prevent and manage obesity-related health issues.

View Article and Find Full Text PDF

Introduction: Myocarditis represents a diverse group of inflammatory diseases affecting the heart muscle, with both infectious and non-infectious etiologies. Among the non-infectious causes, drug-induced hypersensitivity reactions are rare but serious. Isoniazid, a cornerstone in tuberculosis treatment, is known for its hepatotoxicity but has rarely been documented to cause hypersensitivity myocarditis.

View Article and Find Full Text PDF

The evaluation of SARS-CoV-2 mutations at the early stage of the pandemic in Istanbul population.

Ann Clin Microbiol Antimicrob

October 2024

Republic of Türkiye, Istanbul Provincial Directorate of Health, Ministry of Health, University of Health Science, Başakşehir Çam and Sakura City Hospital, Başakşehir, 34480, Istanbul, Türkiye.

Article Synopsis
  • The study assessed SARS-CoV-2 variants in positive patients at Kanuni Sultan Suleyman Training and Research Hospital in Istanbul from January to November 2021, finding a total of 175,367 COVID-19 positive cases among 825,169 patients tested.
  • The most prevalent variants observed were B.1.1.7 (23.2%) and non-mutated (66.1%), with the highest positivity rates in the 6-15 and 66-75 age groups, while women showed higher prevalence across all variants.
  • Understanding these mutations is crucial for controlling COVID-19 transmission, diagnosing the virus, and monitoring immunity levels.
View Article and Find Full Text PDF
Article Synopsis
  • Thoracic trauma is a major cause of death in hospital settings, and this study investigates the link between mortality rates and specific health indicators in patients with isolated thoracic injuries.
  • Conducted in a high-traffic emergency department over four years, the research included 352 patients, identifying that a higher shock index and elevated biochemical markers like glucose/potassium ratios and lactate levels correlate with increased mortality risk.
  • The findings aim to improve predictions of patient outcomes by providing actionable cutoff values for these markers, indicating their potential use as indicators in emergency care settings.
View Article and Find Full Text PDF
Article Synopsis
  • - The study focuses on evaluating the effectiveness of trans-syndesmotic fixation in patients with SER type 4 ankle fractures after assessing syndesmosis using intraoperative tests.
  • - Results show that patients treated with trans-syndesmotic fixation had better outcomes in terms of ankle range of motion and scores on the AOFAS and OMAS compared to those who did not receive this fixation.
  • - However, the lack of fixation for the posterior malleolus significantly increases the risk of developing arthritis, highlighting the need for careful detection and treatment of syndesmotic injuries.
View Article and Find Full Text PDF
Article Synopsis
  • The study looked at how daidzein (DZ), a substance that helps reduce damage and inflammation, affects rabbits with osteoarthritis in their jaw joints.
  • They injected 16 rabbits with a solution to cause osteoarthritis and then split them into two groups—one group got daidzein and the other got saline (a salt solution).
  • After testing, they found no big differences between the two groups in the condition of their joints, meaning the daidzein didn't seem to help as much as hoped.
View Article and Find Full Text PDF