407 results match your criteria: "İstanbul Brain and Spine Center[Affiliation]"

Article Synopsis
  • Cefmetazole is effective against infections caused by extended-spectrum β-lactamase-producing bacteria and may serve as an alternative to carbapenems in treating invasive urinary tract infections.
  • The study involved 127 hospitalized patients, with 81 receiving cefmetazole and 46 receiving meropenem, and tracked outcomes like effectiveness, recurrence, and mortality rates.
  • After adjustments for patient differences, cefmetazole showed clinical and microbiological effectiveness comparable to meropenem, with the same main type of β-lactamase gene identified in all cases.
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Objectives: Carotid artery stenting is sometimes adapted for some at-risk cases; however, appropriate treatment timing with stroke onset is controversial. This study aims to identify factors that have an impact on complications and outcomes, especially in patients at high risk.

Materials And Methods: We examined the characteristics of 152 consecutive patients treated by carotid artery stenting between January 2018 and March 2022 and retrospectively analyzed the risk factors for complications and poor outcomes (modified-Rankin-Scale deterioration), such as patient background, carotid artery stenting risks (access route tortuosity, severe calcification, vulnerable plaque, estimated glomerular filtration rate <30 mL/min/1.

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Background: Neurofibromatosis type 2 (NF2) is a multifaceted disease characterized primarily by benign CNS tumors, especially meningiomas and vestibular schwannomas. There have been several cases of brainstem ischemic stroke in young NF2 patients reported in the literature. To date, there is no unified theory about the connection between NF2 and pediatric stroke.

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In recent years, there has been a significant surge in discussions surrounding artificial intelligence (AI), along with a corresponding increase in its practical applications in various facets of everyday life, including the medical industry. Notably, even in the highly specialized realm of neurosurgery, AI has been utilized for differential diagnosis, pre-operative evaluation, and improving surgical precision. Many of these applications have begun to mitigate risks of intraoperative and postoperative complications and post-operative care.

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Complex regional pain syndrome (CRPS), formerly called reflex sympathetic dystrophy (RSD), is a chronic pain phenomenon associated with an alteration in peripheral and central pain perception in a localized body region. Because of the many risk factors associated with this phenomenon, the true nature of the disease risk and clinical course are a challenge to predict. After the diagnosis is confirmed and treatment is provided promptly, clinicians must consider patient health and function holistically to foster improvement in overall quality of life.

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Article Synopsis
  • Astronauts experience significant bone loss in microgravity, but the exact molecular mechanisms behind this are still not fully understood.
  • Researchers developed a sensitive mass spectrometry analysis system to study proteomic changes in mouse bones, successfully identifying 40 proteins with varying abundance due to the absence of gravity and 22 proteins unaltered by mechanical stimuli.
  • Notably, one protein, SPARCL1, may stimulate bone degradation processes, potentially revealing new insights into bone metabolism and the impact of mechanical forces on bones in space.
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  • This study evaluated how effective and safe thrombectomy is for acute ischaemic stroke patients who had some pre-stroke disability, using data from 2313 patients.
  • Out of the 2136 patients analyzed, 33.3% with pre-stroke disabilities achieved a favorable outcome (mRS score of 0-3) after 90 days, with NIHSS scores being a significant predictor of success.
  • The findings suggest that both intravenous t-PA and thrombectomy are safe and particularly beneficial for patients with lower NIHSS scores experiencing stroke-related disabilities.
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Objectives: Approximately 40% of boys with X-linked adrenoleukodystrophy (ALD) develop inflammatory demyelinating brain lesions (cerebral ALD, cALD) and are at risk for death or severe disability. Risk factors for cALD are poorly understood. Our objective was to evaluate whether vitamin D status, which influences immune function, is associated with risk for cALD.

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Metal fixation systems for cranial bone flaps cut by a drill are convenient devices for cranioplasty, but cause several complications. We use modified craniotomy using a fine diamond-coated threadwire saw (diamond T-saw) to reduce the bone defect, and osteoplasty calcium phosphate cement without metal fixation. We report our outcomes and tips of this method.

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Background: The treatment of Chiari malformations generally consists of posterior fossa decompression. C1 laminectomy is required in selected cases. However, cases of iatrogenic anterior arch fractures at C1 without high-energy trauma have been reported.

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Article Synopsis
  • Common carotid artery occlusion (CCAO) can lead to ischemic stroke, and while bypass surgery is the typical treatment, safer methods are needed.
  • A 68-year-old man with CCAO due to neck radiation therapy experienced decreased vision, prompting a minimally invasive recanalization procedure involving specialized techniques to restore blood flow.
  • The procedure successfully improved the patient's visual acuity and demonstrated that combined endovascular stenting offers a promising alternative treatment for CCAO with fewer complications.
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Objective: Chronic 'displaced' displaced type II fractures, though uncommon, are difficult to manage. They usually require a transoral procedure followed by a posterior instrumented fusion. We describe here, a new method to reduce the fractured displaced odontoid using a posterior cervical approach only.

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This study aimed to test our hypothesis that the cerebellum plays an important role in the generation of the optical-geometric illusion known as the Poggendorff illusion, the mechanism of which has been explained by accumulated experience with natural scene geometry. A total of 79 participants, comprising 28 patients with isolated cerebellar stroke, 27 patients with isolated cerebral stroke and 24 healthy controls, performed Poggendorff illusion tasks and 2 different control tasks. We also investigated core brain regions underpinning changes in the experience of the illusion effect using multivariate lesion-symptom mapping.

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Background The treatment of spinal schwannomas, which is the most common nerve sheath tumor, is total microsurgical resection. The localization, size and relationship with the surrounding structures of these tumors are crucial in terms of preoperative planning. A new classification method is presented in this study for the surgical planning of spinal schwannoma.

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Background: Minimally invasive surgical resection of extraforaminal disc herniation is challenging. The anatomical landmarks are varying from common interlaminar approach. The main risk is to damage the exiting nerve root as it is not yet protected by any bony structure.

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The Efficacy of Blended Learning in a Pediatric Spine Deformity Management Program in Sub-Saharan Africa.

J Am Acad Orthop Surg Glob Res Rev

February 2023

From the Pediatric Orthopedic Surgery, Palestine Polytechnic University, Ramallah, Palestine (Dr. Ahmad); the Teaching and Research Department, An-Najah National University, Nablus, Palestine (Dr. Abushehab); the Department of Neurosciences Grand Hôpital de Charleroi, Charleroi, Belgium (Dr. Waterkeyn); the Muhimbili Orthopedic Institute, Dar es Salaam, Tanzania (Dr. Waterkeyn, Dr. Shabani, Dr. Magogo, Dr. Mcharo, and Dr. Bureta); the Department of Neurological Surgery, Weill Cornell Brain and Spine Center, New York, NY (Dr. Waterkeyn, Dr. Sommer, Mr.Medary, Dr. Hussain, and Dr. Härtl); the Aga Khan University Hospital, Nairobi, Kenya (Ms.Cheserem); the Regional Spinal Department, UOC Ortopedia A, AOUI, Verona, Italy (Dr. Balsano); and the Department of Neurological Surgery, Monroe Carell Jr. Children's Hospital, Vanderbilt University School of Medicine, Nashville, TN (Dr. Bonfield).

Introduction: Our study assessed the efficacy of blended learning, which combines in-person learning and e-learning, in a pediatric scoliosis training program through an international collaborative effort.

Methods: The course comprised two parts: the online portion, where participants reviewed educational materials for 3 weeks and met with faculty once/week for discussion, and the in-person session, where participants reviewed cases in a team-based approach and came to a consensus on treatment strategy, followed by discussion with an international expert. All participants completed a needs assessment (NA) and clinical quiz at three points: before the course, after the online session, and after the in-person session, which covered various topics in pediatric spine deformity.

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Background And Purpose: The effects of therapy and patient characteristics on rehabilitation outcomes in patients with acute stroke are unclear. We investigated the effects of intensive occupational therapy (OT) on patients with acute stroke.

Methods: We performed a retrospective cohort study using the 2005-2016 Japan Rehabilitation Database, from which we identified patients with stroke ( = 10,270) who were admitted to acute care hospitals ( = 37).

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Article Synopsis
  • Dural shrinkage at craniotomy makes it difficult to close openings; a new technique called dural scratching has been developed to simplify this process.
  • In a study of 53 patients with narrow openings, the technique involved creating fine scratches on the dura to relieve tension, allowing for easier closure with sutures.
  • The method resulted in a successful primary closure in 87% of cases and was found to be safe, requiring no special tools and reducing the need for additional grafts.
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Objectives: A foreign body granuloma after an endovascular intervention is a rare complication. Some cases of foreign body granulomas, especially after coil embolization, have been reported. However, only four cases of foreign body granulomas after mechanical thrombectomy (MT) have previously been reported.

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Introduction: Surgical decompression is standard care in the treatment of degenerative spondylolisthesis in patients with symptomatic lumbar spinal stenosis, but there remains controversy over the benefits of adding fusion. The persistent lack of consensus on this matter and the availability of new data warrants a contemporary systematic review and meta-analysis of the literature.

Methods: Multiple online databases were systematically searched up to October 2022 for randomized controlled trials (RCTs) and prospective studies comparing outcomes of decompression alone versus decompression with fusion for lumbar spinal stenosis in patients with degenerative spondylolisthesis.

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Background: Spinal meningiomas are benign and slow-growing intradural tumors. Surgery is the choice of treatment. In this retrospective study, results of minimally invasive Simpson grade 2 resection and its impact on recurrence in 44 spinal meningiomas are reviewed.

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Background: Carotid endarterectomy (CEA) and carotid artery stenting (CAS) are common treatments for ischemic stroke prevention in patients with carotid artery stenosis. However, the beneficial effects of CEA/CAS for cerebral hypoperfusion due to carotid artery stenosis have yet to be fully established. As dizziness is a common symptom in patients with carotid artery stenosis, we aimed to evaluate the effects of CEA/CAS on cerebral function in patients with carotid artery stenosis, using equilibrium function tests.

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 Health promotion programs are effective at reducing cardiovascular diseases (CVDs). One-time health promotion programs are effective at increasing immediate knowledge gain about CVDs. It is unknown if such interventions translate into sustained knowledge gain or actual behavior modifications.

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