Influence of sarcopenia as determined by bioelectrical impedance analysis in acute pancreatitis.

Sarcopenia can be defined as the loss of muscle mass and strength. It is a poor prognostic factor for many diseases. Our study aims to assess the prevalence of sarcopenia in patients with acute pancreatitis using bioelectrical impedance analysis (BIA) and hand dynamometry while also investigating its impact on acute pancreatitis.

Serum Biomarkers IL-6 and HIF-1α in Rosacea: Assessing Their Significance in Disease Pathogenesis and Telangiectasia Formation.

Introduction: Rosacea, a chronic inflammatory disease primarily affecting the central area of the face, is a complex condition whose mechanisms are still not fully understood. However, research has indicated a positive correlation between two molecules: hypoxia-inducible factor-1α (HIF-1α) and interleukin-6 (IL-6). The levels of HIF-1α in rosacea patients have yet to be assessed.

Is Unilateral Extended Pterional Craniotomy Preferable Over Bicoronal (Bifrontal) Craniotomy in Large or Giant Olfactory Groove Meningiomas?

Aim: Bicoronal incision and bifrontal craniotomy are commonly used for resecting large (4-6 cm) or giant ( 6cm) olfactory groove meningiomas (OGMs). Although the bifrontal approach provides good bilateral visual access to the anterior cranial fossa, it is associated with the risk of injury to the frontal bridging veins and superior sagittal sinus, infection, and CSF leakage due to the frontal sinus neighborhood.

Material And Methods: This was a retrospective review of 16patients (nine men and seven women) with large and giant OGMs operated through unilateral extended pterional craniotomy between 2010 and 2022.

Documentation of the current state of cardiopulmonary bypass management in Türkiye.

Since the first successful use of cardiopulmonary bypass (CPB), much has changed in its technology, area of use, and management. Despite suggestions in guidelines, the institutional behavior may change based on institutional experience and established habits. This so-called "deviation" may alter management strategies in favorable or unfavorable ways.

Can some inflammatory parameters predict the survival of patients with malignant pleural effusion?

Background: This study aimed to investigate whether there is a correlation between some serum inflammatory markers and the survival of patients with malignant pleural effusions (MPEs).

Methods: The prospective study included 125 patients (67 males, 58 females; median age: 62 years; range, 40 to 92 years) who underwent thoracentesis for pleural effusion between January 2020 and December 2021. An overall survival analysis was performed, and survival differences between the groups were investigated.

Postoperative physical activity limitations and balance changes on patients who have been operated for breast cancer.

Objective: The purpose of this study is to assess the postoperative physical activity limitations and balance changes in patients who have been operated on for breast cancer. Some physical activity limitations and balance disorders can be expected after breast cancer surgery.

Methods: From 2008 to 2016, 112 patients who underwent breast cancer surgery were included in this study.

Evaluation of corporate experiences during the accreditation process in the field of health - A qualitative study.

Objective: In our study, we attempted to determine the accreditation process experience of hospital senior managers accredited by the Turkish Health Care Quality and Accreditation Institute (TUSKA). Along with the institutions' accomplishments through the accreditation program, the major challenges they faced during the accreditation process were revealed.

Methods: One of the qualitative research designs used was interpretive phenomenological analysis, which was carried out through semi-structured interviews with hospital senior managers.

Brexpiprazole for the Treatment of Agitation in Alzheimer's Disease Dementia: Clinical Uncertainties and the Path Forward.

Brexpirazole was approved for the treatment of nonpsychotic agitation in Alzheimer's disease (AD) dementia by the United States Food and Drug Administration (FDA) in May 2023 after three phase 3 clinical trials found brexpiprazole 2 to 3 mg/day to be an effective and well-tolerated treatment for agitation in AD dementia, albeit with small effect sizes. It appeared to especially benefit dementia patients with severe agitation/aggression, but it took between 6 and 12 weeks across the three studies for the medication to separate from placebo. However, much remains unknown about its place in the psychopharmacological armamentarium for the treatment of AD dementia-related agitation, including the optimal duration of a brexpiprazole trial, bridging options during the time it takes for brexpiprazole to become effective, and whether it should be continued in the presence of or upon emergence of psychosis during treatment.

Gut microbiota profiles of patients with idiopathic pulmonary fibrosis.

: Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia. Multiple genetic factors, environmental exposures, micro-aspirations secondary to gastroesophageal reflux, age, sex, smoking habit, and infections contribute to its etiology; consequently, its pathogenesis remains unclear. The homeostasis of gut microbiota, including bacteria, archaea, and fungi, can influence the functions of both the intestine and remote organs.

Comparison of Ultrasound-Guided Hydrodissection with Various Volumes of 5% Dextrose for Carpal Tunnel Syndrome: A Prospective Randomized Controlled Double-Blind Trial.

Objective: Ideal volume of 5% dextrose (D5W) for median nerve hydrodissection (HD) for treating carpal tunnel syndrome (CTS) is still unknown. This study assessed the efficacy of nerve hydrodissection using varying volumes of D5W for treating mild to moderate CTS.

Design: Eighty participants with unilateral mild to moderate CTS were randomized into groups to receive either 5 ml of normal saline (NS), 5 ml of D5W, 10 ml of NS, and 10 ml of D5W, with each group undergoing one session of ultrasound-guided HD.

Septic Arthritis of the Temporomandibular Joint in a Geriatric Patient: A Case Report.

Septic arthritis of the temporomandibular joint is a rare pathology. There is no consensus in the literature regarding etiopathogenesis and treatment. Pain, swelling, trismus, and mandibular deviation are common.

Histological Evaluation of the Effects of Intra-Articular Injection of Caffeic Acid on Cartilage Repair in a Rat Knee Microfracture Model.

BACKGROUND Cartilage injuries are challenging to treat due to limited self-healing. Standard treatments often lead to the formation of less durable fibrocartilage. Caffeic acid phenethyl ester (CAPE), a polyphenolic compound, can improve cartilage repair.

Effect of using a kaleidoscope projector and matching cards on fear and vital signs in children aged 3-6 years receiving inhaled medication.

Aim: The aim of this study was to investigate the effect of the use of projector kaleidoscope and matching card on children's fear and physiological parameters in children aged 3-6 years receiving inhaled medication.

Methods: This randomised controlled study was conducted with the guidelines of Consolidated Standards of Reporting Trials (CONSORT). The sample of children was allocated to the projector kaleidoscope group (n = 38), matching card group (n = 38) and control group (n = 38).

Does physical performance demonstrate patient-reported outcomes after lumbar spine surgery?

Background: Due to time and setting constraints in clinical practice, performing a comprehensive assessment with both questionnaires and physical performance tests may not be possible. This study aimed to demonstrate the relationship between physical performance and patient-reported outcomes in patients after Lumbar Spine Surgery (LSS).

Methods: A cross-sectional study was conducted with 50 participants who were followed up at least six months after LSS.

Does the thickness of temporal muscle indicate sarcopenia and functional outcome in older patients with acute stroke?

Background And Purpose: Aging, inactivity, malnutrition and diseases cause sarcopenia and stroke is an important reason of sarcopenia. The aim of this study was to determine the sarcopenia and to evaluate the relationship between functional outcome and temporal muscle thickness using brain CT in older acute stroke patients.

Methods: A retrospective study was conducted with acute stroke patients in a single neurology clinic.

Development of the interpretable typing prediction model for osteosarcoma and chondrosarcoma based on machine learning and radiomics: a multicenter retrospective study.

Background: Osteosarcoma and chondrosarcoma are common malignant bone tumors, and accurate differentiation between these two tumors is crucial for treatment strategies and prognosis assessment. However, traditional radiological methods face diagnostic challenges due to the similarity in imaging between the two.

Methods: Clinical CT images and pathological data of 76 patients confirmed by pathology from January 2018 to January 2024 were retrospectively collected from Guizhou Medical University Affiliated Hospital and Guizhou Medical University Second Affiliated Hospital.

Outcomes of neuroendoscopy for suprasellar arachnoid cysts: a single center experiences.

Background: Arachnoid cysts are extra parenchymal, intra-arachnoid fluid collections of unknown origin, similar in content to cerebrospinal fluid. Suprasellar arachnoid cysts are a rarer localization resulting from abnormalities of the Liliequist membrane or cystic dilatation of the interpeduncular cisterna. We aimed to contribute to the literature by presenting a series of suprasellar arachnoid cyst cases with endoscopic intervention and long-term results.

Boron-Doped Nano Hydroxyapatite Grafts for Bone Regeneration in Rat Mandibular Defects.

The aim of this study was to evaluate the potential effects of boron-doped nano hydroxyapatite grafts on craniofacial bone regeneration in critical bone defects in the mandibular corpus of rats, in terms of scintigraphic and histopathological aspects. Forty Wistar albino rats, with an average weight of 200-220 g, aged 16-18 weeks, and all male, were used in the study. The rats were randomly assigned to five groups, each containing 8 rats, as follows: group C1 (no procedure applied to the mandible), group C2 (surgical defect created in the mandible but no treatment applied), group nHA (nano hydroxyapatite applied to the surgical defect area), group nHA + B1 (nano hydroxyapatite + 1% boron applied to the surgical defect area), and group nHA + B2 (nano hydroxyapatite + 2% boron applied to the surgical defect area).

Risk Factors For Progression From Biochemical Leak to Clinically Relevant Postoperative Pancreatic Fistula After Pancreaticoduodenectomy. The Key of the Lock: Prognostic Nutritional Index.

Background/aims: Postoperative pancreatic fistula (POPF), which is considered the most frightening complication after pancreatic oduodenectomy (PD), continues to be a serious problem even in experienced centers. In the present study, we aimed to determine the risk factors that increase the progression from biochemical leak (BL) to clinically relevant postoperative pancreatic fistula (CR-POPF) after PD.

Materials And Methods: We retrospectively analyzed the data of 152 patients who underwent PD.

Is There a Difference between Intralesional Treatments Combined with Internal Urethrotomy?

Background: This study aimed to compare the efficacy of various injection therapy agents used in combination with internal urethrotomy in preventing fibrosis and stricture recurrence.

Materials And Methods: Patients who underwent direct vision internal urethrotomy (DVIU) in our clinic between 2017 and 2022 were retrospectively screened. The patients were divided into four groups: DVIU + intralesional platelet-rich plasma (DVIU + PRP group, n = 21), DVIU + intralesional mitomycin-C (DVIU + MMC group, n = 21), DVIU + intralesional prednisolone (DVIU + prednisolone group, n = 21), and DVIU alone (control group, n = 21).

Monitoring the effect of antiviral treatment on the development of cirrhosis and hepatocellular carcinoma in chronic hepatitis B patients.

Objective: Despite the availability of treatment and vaccines for chronic hepatitis B infection, it remains a public health problem. The use of nucleos(t)ide antiviral agents is effective in preventing complications such as cirrhosis and hepatocellular carcinoma, but despite the reduction, the risk persists. The objective of this study was to assess alterations in aspartate aminotransferase to platelet ratio index and Fibrosis-4 scores and examine the effectiveness of risk estimates for HCC in chronic hepatitis B scores in predicting the risk of hepatocellular carcinoma among chronic hepatitis B patients undergoing prolonged antiviral treatment.

Effective Motivational Interviewing-Based Counseling for Knee Osteoarthritis: A Randomized Controlled Trial.

Objective: This research was conducted to determine the effect on pain, psychosocial adjustment and self-care management of motivational interview-based counseling for individuals with a diagnosis of knee osteoarthritis.

Methods: This study was conducted as a randomized controlled experimental study. The sample size for the study was calculated as 60 individuals (29 intervention, 31 controls) diagnosed with osteoarthritis.