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Fludarabine-induced bradycardia in allogeneic hematopoietic stem cell transplantation: A retrospective study.
J Oncol Pharm Pract
July 2024
Department of Hematology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye.
Article Synopsis
- * A retrospective analysis of 73 patients revealed that while younger age was a significant factor linked to fludarabine-induced bradycardia, the overall doses and durations of fludarabine did not show a statistically significant difference between those with and without bradycardia.
- * It was found that discontinuation of fludarabine improved bradycardia in most cases, and the study emphasizes the importance of monitoring heart rates closely in younger patients receiving this treatment.