7 results match your criteria: " "sotiria" Chest Hospital[Affiliation]"
Genetics in Idiopathic Pulmonary Fibrosis: A Clinical Perspective.
Diagnostics (Basel)
November 2022
2nd Pulmonary Medicine Department, General University Hospital "Attikon", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Background: Unraveling the genetic background in a significant proportion of patients with both sporadic and familial IPF provided new insights into the pathogenic pathways of pulmonary fibrosis.
Aim: The aim of the present study is to overview the clinical significance of genetics in IPF.
Perspective: It is fascinating to realize the so-far underestimated but dynamically increasing impact that genetics has on aspects related to the pathophysiology, accurate and early diagnosis, and treatment and prevention of this devastating disease.
Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study.
Crit Care
September 2022
Médecine Intensive-Réanimation, CHU de Lille, 59000, Lille, France.
Article Synopsis
- Ventilator-associated pneumonia (VAP) frequently affects patients with severe COVID-19 who are on mechanical ventilation, prompting this study to examine how corticosteroids might influence VAP risk.
- A multicenter study analyzed data from 545 patients in 36 ICUs to determine if corticosteroid use impacted VAP incidence, finding that the relationship varied after 48 hours of mechanical ventilation.
- Overall, no significant link was established between corticosteroid treatment and VAP, though the effect seemed to shift over time during the ICU stay.
Invasive pulmonary aspergillosis among intubated patients with SARS-CoV-2 or influenza pneumonia: a European multicenter comparative cohort study.
Crit Care
January 2022
CHU de Lille, Médecine Intensive-Réanimation, 59000, Lille, France.
Article Synopsis
- - This study aimed to compare the incidence of invasive pulmonary aspergillosis (IPA) in critically ill patients with COVID-19 versus those with influenza, using data from a large European cohort that included over 1,000 patients on mechanical ventilation for pneumonia.
- - Results showed that the incidence of putative IPA was significantly lower in the COVID-19 group (2.5%) compared to the influenza group (6%), indicating that COVID-19 patients had a reduced risk for this fungal infection.
- - The study also found that having putative IPA was linked to increased 28-day mortality and longer ICU stays, affirming its severity, but overall the incidence of IPA was low across both patient groups.
Relationship between ventilator-associated pneumonia and mortality in COVID-19 patients: a planned ancillary analysis of the coVAPid cohort.
Crit Care
May 2021
Médecine Intensive-Réanimation, CHU de Lille, F-59000, Lille, France.
Background: Patients with SARS-CoV-2 infection are at higher risk for ventilator-associated pneumonia (VAP). No study has evaluated the relationship between VAP and mortality in this population, or compared this relationship between SARS-CoV-2 patients and other populations. The main objective of our study was to determine the relationship between VAP and mortality in SARS-CoV-2 patients.
View Article and Find Full Text PDFRelationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: a European multicenter cohort study.
Intensive Care Med
February 2021
CHU de Lille, Médecine Intensive-Réanimation, 59000, Lille, France.
Purpose: Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired infections is low. We aimed to determine the relationship between SARS-CoV-2 pneumonia, as compared to influenza pneumonia or no viral infection, and the incidence of VA-LRTI.
Methods: Multicenter retrospective European cohort performed in 36 ICUs.
Viral Profile of COPD Exacerbations According to Patients.
Open Respir Med J
March 2015
Department of Critical Care, University Hospital, ATTIKON, Medical School, University of Athens, Greece.
Background: To compare the differences between elderly and non-elderly patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) due to viral infections.
Methods: Patients with chronic obstructive pulmonary disease (COPD) exacerbation were recruited and classified as elderly (>65 years) and non-elderly (≤ 65 years). Sputum and oropharyngeal samples were assessed, PCR for respiratory viruses and cultures for common pathogens were performed.
Multiple myeloma emerging after chemotherapy for non-small-cell lung cancer.
Med Oncol
March 2009
Department of Respiratory and Critical Care Medicine (KAA), Sotiria Chest Hospital, 152 Mesogion Avenue, Athens, 11527, Greece.
A 67-year-old man underwent total resection of the left lung because of adenocarcinoma, with no evidence of extra-thoracic spread of the cancer. On follow-up, metastatic bone disease was documented and chemotherapy (CMT) which included cisplatin, docetaxel, vinorelbine, and topotecan was administered. Six months after completion of CMT, a rise in total serum protein was noted.
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