Evaluation of calcium, phosphorus and some biochemical parameters in dogs with open and closed cervix pyometra.

The aim of this study was to evaluate the changes in calcium, phosphorus and some biochemical parameters in dogs with open and closed cervix pyometra, which was then compared with a control group. A total of 62 bitches of age group 5-10 years old irrespective of breed were enrolled into the study. Control group consisted of 22 bitches which were clinically healthy and in luteal phase of the estrus cycle.

The Effect of Preoperative Tele-nursing Counseling on Anxiety and Patient Satisfaction in Day Surgery: A Randomized Controlled Trial.

Purpose: This study aimed to investigate the effect of preoperative tele-nursing counseling on anxiety and patient satisfaction in day surgery.

Design: Randomized controlled study design was employed.

Methods: The study was conducted in a city hospital and a university hospital in Istanbul between July 2022 and May 2023 with patients who met the study criteria.

Surgical Management of Concurrent Septic Arthritis and Forearm Necrotizing Fasciitis in an Immunocompromised Patient With a 20-Year History of Chronic Lymphocytic Leukemia: A Case Report.

Shoulder septic arthritis is a severe infection of the shoulder joint, commonly caused by bacteria such as . It leads to inflammation, severe pain, swelling, and reduced mobility in the affected shoulder. The condition is typically diagnosed through clinical evaluation, blood tests, imaging studies, and joint aspiration.

Evaluation of the association of mucosa-associated invariant T (MAIT) cells with childhood asthma.

Background/aim: Innate-like T lymphocytes are a recently defined group of T cells comprising mainly mucosa-associated invariant T (MAIT) cells. The relationship between MAIT cells and childhood asthma is controversial. In this study, we aimed to determine the role of MAIT cells in patients with allergic asthma (AA) and nonallergic asthma (NAA).

Enhanced effects of levan hydrogels and bovine grafts on guided bone regeneration: In-vitro and in-vivo analysis.

This study was performed to evaluate the regenerative capabilities of levan hydrogels when combined with conventional bone graft materials (Bio-Oss®) in guided bone regeneration (GBR). With the growing interest in the application of levan polysaccharide for regenerative purposes over the last decade, a noticeable gap in in-vivo validations remains. This research therefore fills this gap by utilizing the cytocompatibility and cell proliferation potential of levan hydrogels and marks a preliminary effort in its use in combination with Bio-Oss® for bone regeneration, which was examined both in-vitro and in-vivo for the first time.

More Than a Sense: The Sense of Smell and Its Reflection in Mother and Baby: A Comprehensive Review.

Introduction: The sense of smell is one of the most developed and important senses that forms the bond between the newborn and the mother and allows the newborn to reach the mother's breast. The sense of smell begins to form during intrauterine life, and the sense of smell can be a marking tool for a newborn baby, so that the baby can recognize both his mother and his immediate environment and develop his behaviour accordingly. This is necessary not only for feeding babies but also for them to feel safe and peaceful in their new environment.

Assessment of dyslipidemia management in Turkey using a Delphi panel.

This study evaluated the management of dyslipidemia in Turkey with the goal of understanding current diagnosis and treatment patterns, as well as identifying unmet needs in achieving effective low-density lipoprotein cholesterol (LDL-C) targets. Using a Delphi panel consisting of nine expert cardiologists, the study reveals key gaps in dyslipidemia management, particularly in the underutilization of combination therapies, such as statins and PCSK9 inhibitors, which are crucial for achieving LDL-C targets in high-risk patients. The findings indicate that while many patients with very high cardiovascular risk are diagnosed, a significant proportion do not receive optimal treatment to reach LDL-C levels recommended by European guidelines.

The Effect of Maternal Diet and Lifestyle on the Risk of Childhood Obesity.

: Childhood obesity is a global health problem that affects at least 41 million children under the age of five. Increased BMI in children is associated with serious long-term health consequences, such as type 2 diabetes, cardiovascular disease, and psychological problems, including depression and low self-esteem. Although the etiology of obesity is complex, research suggests that the diet and lifestyle of pregnant women play a key role in shaping metabolic and epigenetic changes that can increase the risk of obesity in their children.

The Role of Formononetin in Osteoblast Function and Mineralization Potential with Deproteinized Bovine Bone Material.

Objectives: Dental bone formation involves various cellular and molecular mechanisms, and phytoestrogens such as formononetin (FORM) are promising because of their estrogenic, anti-inflammatory, and antioxidant effects. This study investigated the effect of FORM on osteoblast proliferation, differentiation, and mineralization in combination with spongiosa granulates (BO) in vitro.

Materials And Methods: Human fetal osteoblast cells (hFOB1.

The Anti-Inflammatory Roles of Vitamin D for Improving Human Health.

Vitamin D receptors (VDRs) are present in almost all cells of the immune system, including B cells, T cells, NK (Natural Killer) cells, dendritic cells, and monocytes, as well as the epithelial cells of many organs such as the intestine, pancreas, prostate, lungs, and cardiomyocytes. In addition, some immune cells, including dendritic cells, macrophages, and B and T cells, can synthesize calcitriol by expressing 1α-hydroxylase. Upon binding to VDRs, vitamin D (Vit D) regulates the expression of genes involved in immune responses, including those encoding for cytokines.

Effects of Moringa oleifera extract on biochemical and histological parameters of sodium valproate induced lungs damage.

Sodium valproate- a salt of valproic acid (VPA), is an anticonvulsant used in the treatment of epilepsy and a range of psychiatric conditions that include panic attacks, anxiety, post-traumatic stress, migraine and bipolar disorder etc. VPA can cause direct damage to many tissues due to accumulation of toxic metabolites. Nowadays, phytochemicals are amongst the best options for the treatment of diseases.

Is Teledentistry as Effective as Clinical Dental Diagnosis in Pediatric Patients?

Background: Teledentistry integrates telecommunications with dental practice, facilitating the exchange of clinical information and images for remote dental consultation and treatment planning. This approach enables dental care access across long distances, addressing the need for flexible healthcare solutions.

Aim: This study aimed to evaluate the effectiveness of teledentistry compared to clinical in-person dental diagnosis in pediatric patients during the COVID-19 pandemic.

Do the provisional PRINTO Enthesitis/Spondylitis-Related JIA criteria capture youth with axial spondyloarthritis?

Background: The Paediatric Rheumatology International Trials Organisation (PRINTO) recently undertook an effort to better harmonize the pediatric and adult arthritis criteria. These provisional criteria are being refined for optimal performance. We aimed to investigate differences between patients who did and did not fulfill these PRINTO criteria amongst youth diagnosed with juvenile spondyloarthritis (SpA) that met axial juvenile SpA (axJSpA) classification criteria.

New Onset Absence Status Epilepticus in Pregnancy: A Case Report.

Absence status epilepticus may occur in persons diagnosed with idiopathic/genetic epilepsy as well as in adult and elderly patients. Despite being a rare phenomenon, pregnant women with no previous history of epileptic seizures may be presented with new onset status epilepticus. In this report, we describe the case of a 22-year-old pregnant female with no prior history of seizures.

Clinical outcomes from robotic transabdominal preperitoneal inguinal hernia repair in patients under and over 70 years old: a single institution retrospective cohort study with a comprehensive systematic review on behalf of TROGSS - The Robotic Global Surgical Society.

Aim: This study aimed to assess and compare outcomes of robotic inguinal hernia repair (RIHR) in patients under and over 70 years old, performed by a fellowship-trained robotic surgeon at a single institution.

Methods: A retrospective analysis of patients undergoing robotic primary transabdominal preperitoneal inguinal hernia repair between 2020 and 2022 was conducted. Patients were categorized into two age groups: those under 70 years and 70 years and older.

The Awareness of Methylphenidate and Its Use: Experiences and Perceptions of Medical Students.

Background and objective Over the past decade, the use of psychostimulants typically prescribed for attention-deficit/hyperactivity disorder (ADHD), such as methylphenidate (MP), has become popular among undergraduate students to enhance their academic performance. Despite potential health and legal repercussions, the misuse of these medications has become a significant public health issue, not only in the general population but particularly among students in medical schools across Turkey. This study investigated the prevalence of MP misuse among Turkish medical students and the factors contributing to it.

Surgical Management of Extraskeletal Chondrosarcoma in the Trapezius Muscle: A Report of a Rare Case.

Extraskeletal chondrosarcomas are malignant tumors that develop in soft tissues rather than in bones. Unlike skeletal chondrosarcomas, which are more common, these tumors can occur in areas such as muscles, tendons, or fat. Their unique location in the body makes them distinct and sometimes challenging to diagnose and manage effectively.

A Study on Gastrointestinal Tract of Bardhoka Autochthonous Sheep Breed in Kosovo.

The Bardhoka sheep breed, also known as Dukagjini white sheep (Ovis aries), is considered to be a medium-sized sheep that is a typical grazing ruminant. The aim of this study was to investigate and measure the parameters of the gastrointestinal tract (GIT) of Bardhoka sheep to determine the morphometry, volume, ratio and surface areas of its different parts. The GIT of eight adult healthy Bardhoka sheep with an average body mass (BM) of 57.

Starch-based composite formulation of chickpea flour and black carrot (Daucus carota l.) pomace in extruded snacks: In vitro gastrointestinal behavior and stability of bioactive compounds.

Black carrot pomace (BCP) is a by-product of colorant production, containing various valuable components with the health promoting effects. In this study, for the first time, BCP was incorporated into a starch-based extruded snack formulation using wheat semolina and corn starch. Total phenolic content, total antioxidant capacity, phenolics, and anthocyanins after processing and in vitro gastrointestinal digestion were investigated, and physical and textural properties of the snack products were determined.

The impact of pathogen sensitivity to antibiotics loaded in cement on the number of revisions and costs in the treatment of periprosthetic knee infection.

Objective: This study aims to evaluate the impact of the pathogen's sensitivity to the loaded antibiotics on infection resolution, the number of revisions, and the associated costs in patients undergoing revision total knee arthroplasty (rTKA) due to PJI.

Material And Methods: We reviewed the treatment and follow-up processes of 61 patients who underwent rTKA for late-stage PJI following primary total knee arthroplasty in our clinic. The study included 11 patients in the resistant group and 50 in the sensitive group in line with the power analysis results.

Results of carotid stenting in patients with contralateral internal carotid artery occlusion: a retrospective single-center analysis and 22 years of experience.

Purpose: Patients with contralateral carotid artery occlusion (CCO) represent a subgroup of patients at risk for revascularization procedures. The choice of appropriate revascularization procedure (carotid endarterectomy (CEA) or carotid artery stenting (CAS)) in these patients is controversial. The aim of this study is to share the results of clinical and radiological follow-up after CAS in these patients and to contribute to the literature by evaluating the efficacy and safety of stenting.

De-escalating and discontinuing disease-modifying therapies in multiple sclerosis.

The development of disease-modifying therapies (DMTs) for the treatment of multiple sclerosis (MS) has been highly successful in recent decades. It is now widely accepted that early initiation of DMTs after disease onset is associated with a better long-term prognosis. However, the question of when and how to de-escalate or discontinue DMTs remains open and critical.