Nanostructured TiO Surface Enriched with CeO over Ti Metal for Enhanced Cytocompatibility and Osseointegration for Biomedical Applications.

The present study aims to analyze the thermal regulation of the Ce/Ce ratio on the nanonetwork titania layer over the titanium (Ti) surface developed by the alkali-mediated surface modification approach. The effect of sequential heat treatment from 200 to 800 °C was evaluated for its surface characteristics such as morphology, phase formation, roughness, hardness, hydrophilicity, etc. Surface oxidation by temperatures up to 600 °C demonstrated a progressive increase in the Ce (CeO) content with a rutile TiO network layer over the Ti surface.

Potential Antimicrobial and Cytotoxic Activity of Seed Extract.

Plant-derived phytochemicals are crucial in fighting bacterial infections and in cancer therapy. This study investigates the phytochemical composition of the ethanolic extract obtained from () seeds and assesses its antimicrobial, anticancer, and antioxidant activities. GC-MS analysis found 30 phytochemicals in seeds, including 5 bioactive compounds that have been shown to have antioxidant, antimicrobial, and cytotoxicity properties, through in silico evaluation.

An analysis of availability and implications of unlabeled retracted articles on Sci-Hub.

Background: Researchers are increasingly accessing scientific articles through unauthorized websites like Sci-Hub. Sci-Hub contains retracted articles, including those which are not labelled as retracted, and this is a potential threat to academic research.

Methods: This study analyses the extent of the availability of retracted articles within the Sci-Hub, particularly focusing on the presence of unlabeled retracted articles (URA) which may inadvertently be used in subsequent research, thus propagating flawed findings.

Ruthenium-Hydride Complexes Facilitated Sustainable Synthesis of Isoxazolones via Acceptorless Dehydrogenative Annulation of Alcohols.

A streamlined strategy for the one-pot synthesis of isoxazolone analogues has been developed through an acceptorless dehydrogenative annulation (ADA) pathway by employing new Ru(II) hydride complexes as effective catalysts. New Ru(II) complexes () tailored with N̂O chelating carbazolone benzhydrazone ligands were synthesized and their formation was confirmed using analytical and spectral techniques including FT-IR and NMR. The structural configuration of the complexes featuring an octahedral geometry around the Ru(II) ion was precisely determined by single-crystal X-ray diffraction analysis.

Antibiofilm Activity of Epinecidin-1 and Its Variants Against Drug-Resistant and Isolates from Vaginal Candidiasis Patients.

Indwelling intrauterine contraceptive devices (IUDs) have surfaces that facilitate the attachment of spp., creating a suitable environment for biofilm formation. Due to this, vulvovaginal candidiasis (VVC) is frequently linked to IUD usage, necessitating the prompt removal of these devices for effective treatment.

Two sides of the same coin: Weathering differences of plastic fragments in coastal environments around the globe.

Plastic debris in coastal environments usually undergoes weathering due to various environmental conditions. However, the weathering effects on exposed and shaded sides of the same plastics are underexplored. In this study, 1573 plastic fragments were collected from 15 coastal sites worldwide between December 2021 and December 2022, and weathering experiments were conducted outdoors.

Marine microalgae - Mediated biodegradation of polystyrene microplastics: Insights from enzymatic and molecular docking studies.

Biodegradation of microplastics (MPs) through microalgal strains would be of eco-friendly approach for significant pollution abatement. Polystyrene (PS) is a major contaminant in the marine environment; however studies on marine microalgal degradation of PS MPs have been very limited. In the present study, six marine microalgal strains viz.

Overexpression of an NF-YB gene family member, EaNF-YB2, enhances drought tolerance in sugarcane (Saccharum Spp. Hybrid).

Background: Drought is one of main critical factors that limits sugarcane productivity and juice quality in tropical regions. The unprecedented changes in climate such as monsoon failure, increase in temperature and other factors warrant the need for development of stress tolerant cultivars to sustain sugar production. Plant Nuclear factor (NF-Y) is one of the major classes of transcription factors that have a major role in plant development and abiotic stress response.

Anti-Bacterial and Anti-Dermatophytic Activity of Extracellular Secondary Metabolites of Streptomyces glaucescens NTSB-37 Isolated from Lichen Parmotrema perlatum (Huds.) M. Choisy in Kolli Hills, Tamil Nadu, India.

Lichen-associated endophytic Actinobacteria, particularly Streptomyces species, are recognized for their production of bioactive secondary metabolites with significant pharmaceutical potential. With the escalating prevalence of diseases, Streptomyces species are being investigated for its natural source of antimicrobial compounds for new antibiotics. This study focuses on the bioactive properties of secondary metabolites from lichen-associated endophytic Actinobacteria, focusing on Streptomyces glaucescens NTSB-37 isolated form lichen, Parmotrema perlatum (Huds.

Metagenomic analysis and bioactive profiling of kombucha fermentation: antioxidant, antibacterial activities, and molecular docking insights into gastric cancer therapeutics.

Kombucha is fermented and produced with a biofilm called a symbiotic culture of bacteria and yeast, which is drunk all over the world for its beneficial effects on human health and energy levels. The metagenomic study of kombucha frequently detected microorganisms in proteobacteria, firmicutes, and actinobacteria. And also, yeast and fungi are Ascomycota and Basidiomycota is present in green leaf and sugarcane juice fermented kombucha.

The first report on emerged microplastics in deep-sea sediment: Insights from the Central Indian Ocean Basin.

Microplastics (MPs, <5 mm) are widespread in coastal ecosystems and pose a growing global concern; however, their presence in deep-sea environments remains underexplored, especially in the Indian region. This study addresses this gap by providing the first comprehensive documentation of MPs in the Central Indian Ocean Basin (CIOB) at a depth of 5000 m, marking the initial effort to assess their presence and abundance in deep-sea core samples. The study investigated the MP concentration, composition and potential sources, revealing a size range between 10 μm and 4900 μm, with average abundances recorded at BC20 (10.

Sustainable Synthesis of Substituted 1,3,5-Triazines by [ONO]-Pincer-Supported Nickel(II) Complexes via an Acceptorless Dehydrogenative Coupling Strategy.

A facile, cost-effective, and sustainable synthesis of substituted triazines from primary alcohols by newly synthesized nickel pincer-type complexes (-) has been described. Herein, we report the synthesis of a set of three well-defined Ni(II) O^N^O pincer-type complexes, structurally characterized by analytical, spectral, and X-ray diffraction techniques. Further, the nickel complexes are explored as efficient catalysts (4 mol %) for the construction of 2,4,6-substituted 1,3,5-triazines from readily available alcohols via an acceptorless dehydrogenative coupling (ADC) strategy.

Insights into Cancer Cell Imaging Probes Based on Chalcone Scaffolds: Theoretical and Experimental Perspectives.

The research article details the synthesis of chalcone-chromone-based scaffolds via multicomponent reactions. These compounds were characterized using conventional spectroscopic methods, including NMR (H and C), FT-IR, and HR-MS. Among the synthesized scaffolds, AZBNPy stood out, exhibiting exceptional DNA and protein targeting capabilities with superior binding parameters.

Synchronization transitions in adaptive simplicial complexes with cooperative and competitive dynamics.

Adaptive network is a powerful presentation to describe different real-world phenomena. However, current models often neglect higher-order interactions (beyond pairwise interactions) and diverse adaptation types (cooperative and competitive) commonly observed in systems such as the human brain and social networks. This work addresses this gap by incorporating these factors into a model that explores their impact on collective properties such as synchronization.

Enhanced two-photon absorption in hydrothermally synthesized LaOTe nanorods for visible light photodetection.

In the present study, lanthanum oxytellurate (LOT) samples with varying La : Te ratios are successfully synthesized using a simple hydrothermal method that has enormous advantages. The prepared samples crystallize in a LaOTe composite phase with an orthorhombic crystal system. A nanorod-like morphology is observed for each sample, and the presence of constituent elements is verified from EDX results.

Deciphering Structural Dynamics of Atherosclerosis Proteins: Insights from Phytochemicals that Interceded Functional and Structural Changes in Targeted Atherosclerotic Proteins.

Atherosclerosis (ASC) is characterized by foam cell-mediated plaque formation, vascular endothelial inflammation, and lipidosis and is the rudimentary cause of cardiovascular diseases. This is the pre-eminent global factor of mortality. This etiological paradigm is significantly influenced by several proteins, where 23 pivotal proteins involved in ASC were meticulously gleaned on the basis of literature studies.

Algae-mediated copper nanocatalyst for aerobic oxidation and dye decolourization via sustainable wastewater treatment.

In recent years, several physicochemical methods have been proposed for decolourising textile dyes; however, few have been adopted by the textile industry because of factors such as high cost, low efficiency, and limited applicability to a wide range of dyes. The current study focuses on synthesising algae-mediated Cu and CuO nanocatalysts (Alg-Cu and Alg-CuO) using natural waste materials from green algae. The synthesised Alg-CuO nanocatalyst was characterised and confirmed using SEM, TEM, UV, FT-IR, XRD, XPS, GC-MS, and TGA.

QbD-guided phospholipid-tagged nanonized boswellic acid naturosomal delivery for effective rheumatoid arthritis treatment.

Studies have reported the potential role of Boswellic acids (BAs), bioactive pentacyclic triterpenes from (BS), in treating rheumatoid arthritis (RA). However, poor water solubility and limited oral absorption are restricting factors for its better therapeutic efficacy. Based on these assumptions, the current study aimed to develop naturosomal delivery of BAs to boost their extremely low bioavailability, colloidal stability, and water solubility.

Ecophysiological status of copepods in the oxygen minimum zone of Eastern Arabian Sea.

Eutrophication of marine ecosystems is a global problem, particularly in a changing climate and the spreading of Oxygen Minimum Zones (OMZs). The eastern Arabian Sea has both seasonal and permanent/perennial OMZs, but our understanding of the fauna there is extremely poor. So, this study investigated the composition and physiological status (alive or dead) of zooplankton (copepods) in the two OMZs.

Stable neodymium gallium oxide (NdGaO and NdGaO) phases: a study on their asymmetric supercapacitor applications.

Rare-earth-based nanomaterials with exceptional electrochemical properties can be obtained a simple, low-cost, environment-friendly citrate-gel-matrix approach. Owing to their high specific capacitance, strong conductivity, and electrochemical stability, gallium-based materials are capable of withstanding numerous charge-discharge cycles, thus extending the life cycle of a supercapacitor. This tunability enabled researchers to alter the morphology and composition of the electrode to enhance supercapacitor performance.

Unraveling the potential of Epicatechin gallate from crataegus oxyacantha in targeting aberrant cardiac Ca2+ signalling proteins: an in-depth investigation for heart failure therapy.

The cardiovascular sarcoplasmic reticulum (SR) calcium (Ca2+) ATPase is an imperative determinant of cardiac functionality. In addition, anomalies in Ca2+ handling protein and atypical energy metabolism are inherent in heart failure (HF). Moreover, Ca2+ overload in SR leads to mitochondrial matrix Ca2+ overload, which can trigger the generation of Reactive Oxygen Species (ROS), culminating in the triggering of the Permeability Transition Pore (PTP) and Cytochrome C release, resulting in apoptosis that leads to arrhythmias and numerous disorders.

CoFe-MOF nanoarray as flexible microelectrode for electrochemical detection of catechol in water samples.

A simple, selective, and straightforward enzyme-free electrochemical sensor has been designed and developed using cobalt hexacyanoferrate metal-organic framework (CoFe-MOF) nanoarray. The prepared CoFe-MOF nanoarray has been successfully grown over a carbon cloth (CC) to form CoFe-MOF/CC as a flexible microelectrode for the detection of catechol. The surface of the activated CC was covered uniformly with CoFe-MOF in the form of nanoarray and exhibited double-shelled cubic morphology.