5 results match your criteria: "'Luigi Sacco' General Hospital[Affiliation]"
Modelling of Lesions Associated with Functional Mitral Regurgitation in an Ex Vivo Platform.
Ann Biomed Eng
October 2017
Department of Electronics, Information and Bioengineering, Politecnico di Milano, Via Golgi 39, 20133, Milan, Italy.
Functional mitral regurgitation (FMR) is a complex pathology involving valvular and subvalvular structures reconfiguration, and its treatment is considered challenging. There is a lack of experimental models allowing for reliable preclinical FMR treatments' evaluation in a realistic setting. A novel approach to simulate FMR was developed and incorporated into an ex vivo passive beating heart platform.
View Article and Find Full Text PDFA novel system for the treatment of aortic annular dilation: an ex vivo investigation.
Eur J Cardiothorac Surg
December 2017
ForcardioLab, Fondazione per la Ricerca in Cardiochirurgia ONLUS, Milan, Italy.
Objectives: The main reason for aortic repair failures is recurrent annular dilatation. The fibrous portion of left ventricular outflow tract dilates. A novel device was designed to tackle this problem.
View Article and Find Full Text PDFFunctional Tricuspid Regurgitation Model in a Beating Heart Platform.
ASAIO J
February 2018
From the *Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy; †ForcardioLab - Fondazione per la Ricerca in Cardiochirurgia ONLUS, Milan, Italy; and ‡Cardiovascular Department, 'Luigi Sacco' General Hospital, Milan, Italy.
Currently, clinicians are seeking new, minimally invasive treatment options for functional tricuspid regurgitation (FTR). Challenging tricuspid complexity requires the evaluation of the treatment techniques in adequate and realistic preclinical scenario. The purpose of this article is to describe the design and functional assessment of a novel passive beating heart model of the pulmonary circulation with the possibility to tightly control FTR.
View Article and Find Full Text PDFTranscatheter Edge-to-Edge Treatment of Functional Tricuspid Regurgitation in an Ex Vivo Pulsatile Heart Model.
J Am Coll Cardiol
September 2016
ForcardioLab-Fondazione per la Ricerca in Cardiochirurgia ONLUS, Milan, Italy; Cardiovascular Department, 'Luigi Sacco' General Hospital, Milan, Italy; Università degli Studi di Milano, Milan, Italy.
Background: Although associated with left heart pathologies, functional tricuspid regurgitation (FTR) is often left untreated during left heart surgery. Hence, owing to its degenerative character, reoperation is often needed, encompassing an impressive (25% to 35%) mortality rate. Thus transcatheter approaches to FTR are raising great interest.
View Article and Find Full Text PDFClinical and pathological findings of a fatal systemic capillary leak syndrome (Clarkson disease): a case report.
Medicine (Baltimore)
March 2015
From the Internal Medicine Unit (AZ, FS, GF, LB, MDV, FP); Pathology Unit (BM), Angelo General Hospital, Venice; Internal Medicine Unit (MC), Luigi Sacco General Hospital, University of Milan; and Internal Medicine Unit (MS, GM), San Donà di Piave General Hospital, Venice, Italy.
Article Synopsis
- - Systemic capillary leak syndrome (SCLS) is a rare condition characterized by episodes of low blood pressure, low albumin levels, and increased concentration of blood components caused by fluid leakage from blood vessels, which can be life-threatening.
- - A 49-year-old man with no prior health issues experienced a severe episode following flu-like symptoms, resulting in critical health complications and high levels of various lab markers, leading to a diagnosis of SCLS after initial treatments with steroids and plasma expanders.
- - Despite treatment, the patient suffered a new crisis and ultimately died from severe complications, highlighting the unpredictable nature of SCLS and the need for better management strategies for acute episodes due to limited research on the condition.