Clinical features, treatment options and outcomes in primary cutaneous B-cell lymphomas: a real-world, multicenter, retrospective study.

Background: Primary cutaneous B-cell lymphomas (PCBCLs) are rare cutaneous neoplasms with limited literature regarding treatment options and associated treatment outcomes. This study aimed to investigate and present real-world treatment outcomes in patients with PCBCLs.

Methods: All patients with PCBCL who were treated in five major referral centers for cutaneous lymphoma in Greece over 10 years were retrospectively included with their baseline characteristics and treatment-associated outcomes collected and analyzed.

The Microbial Perspective: A Systematic Literature Review on Hypertension and Gut Microbiota.

Background: Understanding the causes of hypertension is important in order to prevent the disease. Gut microbiota (GM) seems to play an important role, but the detailed physiology remains elusive, with alpha diversity being the most studied indicator.

Objectives: This review aimed to systematically synthesize data on gut microbiota (alpha diversity) and hypertension.

Psychopathological Profile of Patients with Moderate-to-Severe Plaque Psoriasis and Its Correlation to DLQI: Results from a Prospective, Monocentric Clinical Study.

: Psoriasis is associated with a high psychological burden and comorbidities, such as depression and anxiety. The aim of this study was to evaluate the psychopathological profile of patients with moderate-to-severe plaque psoriasis under systemic treatment and to explore the association between DLQI and alexithymia, depression, and other psychopathological disorders. : In this monocentric, prospective clinical study, 104 adult patients with moderate-to-severe plaque psoriasis were evaluated according to the disease severity (measured by PASI) influence of psoriasis on their quality of life (measured by DLQI) and their psychopathological profile (measured by the BDI, TAS-20, and SCL-90 questionnaires).

Non-alcoholic Wernicke Encephalopathy in a Young Patient with Adenocarcinoma of the Colon: A Case Report and Review of the Literature.

Introduction: Wernicke Encephalopathy (W.E.) is an acute neurological disorder induced by thiamine deficiency.

Correlation of Psychosomatic Factors and Personality Traits With the Severity of Melanoma.

Background/aim: Melanoma, as a type of skin cancer, has undoubtedly gathered the interest of the global community in recent years, due to its rising incidence. Patients suffering from melanoma experience effects on their mental health, mainly depression and anxiety disorders. The present study aimed to examine the association of melanoma with the psychosomatic burden, personality traits, and demographic factors of the participants.

A Comprehensive Review of the Importance of the Main Comorbidities in Developing Cognitive Disorders in Patients With Spinal Cord Injuries.

Spinal cord injuries (SCI) refer to lesions in the spinal cord due to direct trauma (traumatic SCI-TSCI), such as vehicle accidents, falls, and violent events, or other pathological conditions (non-traumatic SCI) such as metabolic disorders, inflammation, or degenerative disorders. Depending on the location of the injury, patients may experience movement and/or sense disabilities in their lower limbs, torso, or upper limbs. Even though poorly studied, it has been found that such patients have a higher risk of developing cognitive disorders, such as deficits in concentration, short and long memory, comprehension, and problem-solving, as well as mental deficits in the form of difficulty socializing and expressing emotions.

When to Intervene in Acute Necrotizing Pancreatitis: A Narrative Review of the Optimal Timing for Intervention Strategies.

: Acute necrotizing pancreatitis (ANP) is the acute inflammation of pancreatic parenchyma, most commonly due to alcohol abuse or cholelithiasis. The treatment can be either conservative or invasive, including a variety of techniques; however, it has not yet been established if the intervention should be early or if it should be delayed. The aim of this review is to investigate the optimal time for intervention in ANP.

The effect of lipid-lowering treatment on indices of MASLD in familial hypercholesterolemia patients.

Background & Aims: The effect of lipid-lowering treatment (LLT) on metabolic dysfunction associated steatotic liver disease (MASLD) is unclear. This is relevant for patients with familial hypercholesterolemia (FH) who are on lifelong LLT. We aimed to evaluate the effect of LLT on MASLD indices in this population.

Scanning more corresponds to more accuracy in hemodialysis patients: 28-zone protocol's superior findings from an observational study.

Aims: Hypervolemia remains a problem in hemodialysis patients and is associated with hypertension, cardiovascular events and mortality. Lung Ultrasound (LUS) is a technique that detects hypervolemia via 4 different protocols depending on the number of sites checked on the chest wall. It has not been established which protocol should be preferred in the literature.

Instruments Used for the Assessment of SUI Severity in Urogynecologic Surgical Trials: A Scoping Review.

Introduction And Hypothesis: Various instruments are used to evaluate the severity of stress urinary incontinence (SUI) in clinical trials for SUI surgery. We conducted a scoping review with the primary aim of investigating the use of such instruments.

Methods: A comprehensive search in PubMed/MEDLINE, Cochrane Library, ClinicalTrials.

Effect of HIV on Lung Function and Structure: A Systematic Review and Meta-analysis.

Rationale: Obstructive lung disease (OLD) pathogenesis includes inhalational (e.g., smoking) and non-inhalational mechanisms (e.

Analysis of angiotensin II type 1 receptor and osteoprotegerin gene polymorphism on the risk of cardiovascular mortality risk and progressivity of chronic kidney disease.

Background: Chronic kidney disease (CKD) is a significant global public health issue with increased risk of atherosclerotic cardiovascular disease (ASCVD) and cardiovascular mortality. Single nucleotide polymorphisms (SNPs) on angiotensin II type 1 receptor (AT1R) A1166C and osteoprotegerin (OPG) C950T gene have received significant attention as a genetic risk factor for cardiovascular disease and CKD.

Methods: This was a cross-sectional study involving 75 adults with CKD recruited from Nephrology Outpatient Clinics of Universitas Airlangga Hospital, Surabaya, Indonesia.

The role of abdominal muscle training in combination with pelvic floor muscle training to treat female urinary incontinence - a pilot 12-week study.

Introduction: Current literature is inconclusive as to whether transversus abdominis (TrA) training can provide an additional benefit to pelvic floor muscle (PFM) training in female stress urinary incontinence (SUI). We designed a study to investigate the effect of PFM and TrA training on incontinence parameters.

Material And Methods: 60 females with SUI were randomised to PFM training alone or PFM plus TrA training.

The Association between Food Groups, Nutraceuticals, and Food Supplements Consumption on Vascular Health Outcomes: A Literature Review.

Vascular aging, marked by alterations in the structure and function of blood vessels, including heightened arterial stiffness and impaired endothelial function, is linked to a higher likelihood of developing cardiovascular and age-associated pathological conditions. Oxidative stress and inflammation are key stimulation factors in vascular aging. Engaging in healthy dietary habits could enhance the functioning of blood vessels.