4,003 results match your criteria: ""Pamukkale" University[Affiliation]"

In the period between October 2017 and September 2019, field studies were conducted with the aim of elucidating the gall wasp (Hymenoptera: Cynipidae and Diplolepididae) fauna of the Eastern Black Sea Region (Northeastern Türkiye). Gall samples were collected from 695 different localities within the research area, comprising a total of seven provinces (Artvin, Bayburt, Giresun, Gümüşhane, Ordu, Rize and Trabzon). As a result of these investigations, a total of 90 species belonging to 18 genera were recorded.

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Aim: Investigating the effect of Neurodevelopmental Treatment (NDT) on the risk of falling and balance in children diagnosed with Cerebral Palsy (CP).

Methods: Participants were randomly assigned to experimental and control groups. At baseline, the balancing skills of all participants was assessed using the Pediatric Balance Scale, and the gait parameters and fall risk was measured using the LEGSys.

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Background: This study aimed to investigate the causes of failure after the ileal pouch-anal anastomosis (IPAA) procedure for ulcerative colitis (UC) and to determine the independent risk factors affecting their quality of life.

Methods: This multi-center cohort study included all UC patients who underwent IPAA at nine referral centers in Türkiye from 2010 to 2018. Centers were categorized as high-volume (≥10 cases/year) or low-volume (<10 cases/year).

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Objective: Fear of movement in patients with traumatic hand-arm injuries can negatively affect functional outcomes. Therefore, it is important to evaluate fear of movement in this patient population. The aim of this study was to investigate the validity and reliability of the Tampa Scale for Kinesiophobia in patients with traumatic hand-forearm injuries.

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Objective: Controlling Nutritional Status score was previously described and has been used in predicting short- and long-term outcomes in different patient populations. The aim of this study was to test the relationship between Controlling Nutritional Status score and in-hospital mortality in coronary care unit patients (MORCOR-TURK population).

Methods: In this multicenter and national study, all patients with an available Controlling Nutritional Status score were included in the analysis.

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Bibliometric Analysis and Network Visualization of Nanozymes for Microbial Theranostics in the Last Decade.

Appl Biochem Biotechnol

December 2024

Faculty of Science, Department of Biology, Molecular Biology Section, Pamukkale University, 20160, Denizli, Türkiye.

Nanozymes are a class of nanomaterials that are capable of mimicking the activities of natural enzymes. They are currently receiving considerable attention due to their advantageous properties. The objective of this study is to provide a comprehensive analysis of the advancements and trends in nanozymes for microbial theranostics research over the past decade through a detailed bibliometric approach.

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The research explored the influences of 2% and 4% heat-treated fresh elderberry fruit mash supplement and 0.5% and 1% dried elderberry powder supplement before and after fermentation in kefir production on certain features of kefir beverage. Antioxidant activity, total monomeric anthocyanin, and total phenolic content were 16.

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Article Synopsis
  • Early identification of heart issues and disease severity in multisystem inflammatory syndrome is crucial for effective management, which this study investigates through Pentraxin-3 levels.
  • The research involved 56 patients and 26 healthy controls, finding significantly higher Pentraxin-3 levels in patients, especially those with cardiac involvement or severe disease.
  • Elevated Pentraxin-3 may serve as a predictor for clinical outcomes in these patients, but further studies are required for confirmation.
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  • Chronic obstructive pulmonary disease (COPD) often leads to hospital readmissions, with a study involving 415 patients in Turkey revealing significant readmission rates of 42.4% within 30 days and 46% within 90 days after severe exacerbations.
  • Key risk factors for 30-day readmissions include high anxiety and depression scores, a history of severe exacerbations, hospital-acquired pneumonia, and frequent antibiotic use.
  • For 90-day readmissions, factors such as severe heart regurgitation, multiple moderate exacerbations, immunosuppression, and being hospitalized via the emergency department were significant contributors.
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Article Synopsis
  • COPD exacerbations can lead to increased morbidity and mortality, with prolonged hospital stays linked to various risk factors despite optimal care.
  • A study analyzed 434 COPD patients to identify factors influencing hospital length of stay (LOS), categorizing them into patient-related, disease-related, treatment-related, and hospital utility-related.
  • Key findings indicated that factors like biomass exposure, previous non-invasive mechanical ventilation, low bicarbonate levels, and increased oxygen needs were associated with difficult-to-manage exacerbations and longer hospitalizations.
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Beyond Borders, Beyond Bias: Unveiling Medical Xenophobia Among Resident Physicians in Türkiye.

J Immigr Minor Health

November 2024

Alaşehir District Health Directorate, Manisa, Türkiye, Turkey.

Xenophobia among healthcare professionals can significantly impact the quality of care provided to immigrant and refugee populations, particularly in countries with high influxes such as Türkiye. This study evaluated xenophobia among resident physicians at Pamukkale University Hospital and identified factors influencing these attitudes. This cross-sectional study involving 271 resident physicians at Pamukkale University Hospital was conducted between August 1 and August 20, 2022.

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Methotrexate (MTX) is a generally applied chemotherapeutic medicine in most cancers treatment. Morin hydrate, a robust antioxidant, is a secondary metabolite observed in numerous plants, along with figs, white mulberries, and others. The hypothesis of this study is that morin hydrate can effectively reduce MTX-induced kidney injury in rats by increasing antioxidant enzyme activity and inhibiting apoptotic processes.

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The goal of the current study was to investigate the inhibitory activity of six phenolic compounds, i.e., rosmarinic acid, gallic acid, oleuropein, epigallocatechin gallate (EGCG), 3-hydroxytyrosol, and quercetin, against β-site amyloid precursor protein cleaving enzyme-1 (BACE1), also known as β-secretase or memapsin 2, which is implicated in the pathogenesis of Alzheimer's disease (AD).

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Background: Coactivation between tonic and phasic muscles is essential for correct posture and movement. Impaired movement patterns and postural changes facilitate the flexor response to protect painful tissue in the injured area. Tone changes between tonic and phasic muscles lead to an imbalance in the rotator cuff (RC) muscles.

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The aim of this study was to compare the effects of Neuromuscular Integrative Action (NIA) and Pilates exercises on physical fitness and psychological effects in sedentary women. The groups were randomly divided into Pilates (n = 22) and NIA (n = 21) groups using the closed envelope method. 43 sedentary women aged 20-45 years were included in the study.

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Objective: Systemic sclerosis (SSc) is a chronic disease that can cause interstitial lung disease (ILD), a poor prognostic factor in SSc patients. Given the concerns over radiation exposure from repeated CT scans, there is a growing interest in exploring radiation-free imaging alternatives like MRI for ILD evaluation. The aim of this study is to assess the efficacy of three-dimensional zero echo time (3D-ZTE) MRI in assessing SSc-related ILD compared to the thin-slice chest CT.

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Objective: In this retrospective study, we aimed to investigate the clinical, hormonal, and radiological characteristics of patients with adrenal incidentalomas (AIs), to assess the prevalence of metabolic syndrome components in patients with AIs, and to determine whether changes in tumor size or hormonal activity occur during long-term follow-up in patients with AIs.

Methods:  We retrospectively analyzed data from 384 patients diagnosed with AI between 2010 and 2020. Data regarding radiological, hormonal, and metabolic investigations in diagnosis and also during follow-ups were collected.

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Objectives: Acute central nervous system (CNS) infections in children can lead to neurological complications and mortality. This study aimed to identify the clinical manifestations, laboratory parameters, and cerebrospinal fluid characteristics indicative of CNS infections and define the risk factors that lead to pediatric intensive care unit (PICU) admission in the pediatric population of Şanlıurfa, a city in southeastern Turkey.

Methods: This retrospective analysis included patients aged 1 month to 18 years who were treated for acute CNS infections in the Şanlıurfa Training and Research Hospital between January 2020 and May 2023.

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Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options.

Res Pract Thromb Haemost

October 2024

Department of Internal Medicine, Division of Hematology, Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.

Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

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Background: Pain and sedation management is an integral part of pediatric intensive care practice. Sedoanalgesia management must be balanced in order to optimize comfort and avoid complications. In order to achieve this balance, sedoanalgesia management needs to be clarified in pediatric intensive care units (PICU).

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Introduction: Topical therapies are used in almost all patients with psoriasis. A novel fixed topical combination cream (GN-037) with a lower concentration (0.0356%) of clobetasol 17-propionate (CP) was developed together with urea, salicylic acid, and retinoic acid to provide a better benefit-risk ratio.

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Purpose: To evaluate the Superb Microvascular Imaging (SMI) vascular patterns and vascularity index (VI) values of malignant focal liver lesions (FLLs), assess their role in differential diagnosis, and examine interobserver agreement.

Materials And Methods: A total of 107 patients (52 males, 55 females; mean age 62 ± 12.8 years, range 25-87) referred to the interventional radiology clinic for FLL biopsy between April 2022 and April 2023 were analyzed.

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Introduction: The natural history, the progression of a disease process in an individual over time, has not yet been fully elucidated in hidradenitis suppurativa (HS). In this large multicenter study, we aimed to investigate the natural history of HS and its gender differences.

Methods: This cross-sectional study included 827 patients.

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This study aimed to assess the extent of cognitive impairment in children and adolescents with Juvenile Idiopathic Arthritis (JIA). While cognitive deficits are recognized in other systemic rheumatic diseases, exploration within the pediatric JIA population remains limited. The investigation utilized a comprehensive approach to examine neuropsychological test performance.

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