INTEGRATED MANAGEMENT OF OVARIAN ENDOMETRIOMAS: PRE- AND POST-SURGICAL USE OF DIENOGEST.

Aim: to evaluate the efficacy of an integrated management approach for ovarian endometriomas using Dienogest administered both before and after laparoscopic cyst enucleation in women with infertility.

Materials And Methods: The prospective, comparative clinical trial included 44 patients aged 18-35 years with ovarian endometriomas and infertility. Patients were randomly divided into two groups: the study group (20 participants) received Dienogest for six months before and after laparoscopic cyst enucleation, while the control group (24 participants) underwent laparoscopic cyst enucleation without additional hormonal treatment.

Pseudo-Pseudo Meigs' Syndrome in a 40-Year-Old Woman Without a Prior Systemic Lupus Erythematosus Diagnosis.

Pseudo-pseudo Meigs' syndrome (PPMS), also known as Tjalma syndrome, is an exceptionally rare condition marked by pleural effusion, ascites, and elevated CA-125 levels, usually in the context of systemic lupus erythematosus (SLE) without any associated ovarian tumors. We report the case of a 40-year-old woman who presented with a four-month history of fatigue, nausea, weight loss, abdominal pain, and pleural effusion. Initial diagnostic workup revealed ascites, elevated CA-125 levels, and pleural effusions, with no evidence of malignancy.

Polymicrobial outbreak of carbapenemase producing Enterobacterales managed using universal admission and discharge screening and water-safe built environment.

Background: Carbapenemase-producing Enterobacterales (CPE) are antimicrobial resistant (AMR) bacteria which are increasing in incidence globally. Hospitals act as powerhouses for transmission of such bacteria with some regions experiencing prolonged outbreaks and high prevalence for several years. Current screening strategies are based on admission and risk-based screening only.

Endoportal Radiofrequency Ablation and Stent Placement in Patients with Portal Vein Tumor Thrombosis from Hepatocellular Carcinoma: A Study on Feasibility and Safety.

: Hepatocellular carcinoma (HCC) is the most common type of liver cancer, with 10-40% of cases involving portal vein tumor thrombosis (PVTT), leading to poor outcomes and a short survival. The effectiveness of PVTT treatment in patients with HCC is still controversial. : This prospective dual-center study cohort comprised 60 patients with HCC and PVTT who underwent PVR-EPRFA-ST using a novel intravascular radiofrequency system followed by vascular stent placement across the PVTT stenosed segment under fluoroscopy guidance.

Myocarditis Following COVID-19 Vaccination: Cardiac Imaging Findings in 118 Studies.

We reviewed the reported imaging findings of myocarditis in the literature following COVID-19 vaccination on cardiac imaging by a literature search in online databases, including Scopus, Medline (PubMed), Web of Science, Embase (Elsevier), and Google Scholar. In total, 532 cases of myocarditis after COVID-19 vaccination were reported (462, 86.8% men and 70, 13.

COMPARATIVE ANALYSIS OF CURRENT SURGICAL APPROACHES TO THYMIC TUMORS TREATMENT.

The aim of the work was a comparative analysis of scientific sources, covering current surgical approaches in the treatment of thymus tumors, as well as the analysis of the results of own experience in minimally invasive surgery for thymus neoplasm. Thymic hyperplasia include tumor-like disorders, cysts and thymic tumors, the latter compose for 60-90% of all thymic lesions. Over the past ten years, due to the development of technologies, a new trends of surgical treatment of thymic tumors has been proposed - minimally invasive techniques, which all over the world changes the historical dogmas concerning thymus surgery, since associated with shorter hospital stays, less intraoperative bleeding, the best aesthetic outcomes.

Percutaneous catheter drainage of pancreatic associated pathologies: A systematic review and meta-analysis.

Purpose: The main goal of this systematic review was to assess the technical and clinical success, adverse events (AEs), surgery, and overall mortality proportion after percutaneous catheter drainage (PCD) of two pancreatic lesions.

Methods: An extant search in online databases including Scopus, PubMed (Medline), Embase (Elsevier), Web of Science, Cochrane library, and Google Scholar, was conducted to recognize all studies that used PCD intervention in the management of pancreatic necrosis (PN) and pancreatic pseudocysts (PP). Random effects meta-analysis was performed, and Cochrane's Q test and Istatistic were utilized to determine heterogeneity.

A Systematic Review of Imaging Studies in Olfactory Dysfunction Secondary to COVID-19.

Rationale And Objectives: Hyposmia/anosmia is common among patients with coronavirus disease-2019 (COVID-19). Various imaging modalities have been used to assess olfactory dysfunction in COVID-19. In this systematic review, we sought to categorize and summarize the imaging data in COVID-19-induced anosmia.

Safety, efficacy, and tolerability of efgartigimod in patients with generalised myasthenia gravis (ADAPT): a multicentre, randomised, placebo-controlled, phase 3 trial.

Background: There is an unmet need for treatment options for generalised myasthenia gravis that are effective, targeted, well tolerated, and can be used in a broad population of patients. We aimed to assess the safety and efficacy of efgartigimod (ARGX-113), a human IgG1 antibody Fc fragment engineered to reduce pathogenic IgG autoantibody levels, in patients with generalised myasthenia gravis.

Methods: ADAPT was a randomised, double-blind, placebo-controlled, phase 3 trial done at 56 neuromuscular academic and community centres in 15 countries in North America, Europe, and Japan.

Lymphadenopathy Following COVID-19 Vaccination: Imaging Findings Review.

Rationale And Objectives: Despite all the benefits and effectiveness of the coronavirus disease 2019 (COVID-19) vaccines mentioned in recent clinical trials, some post-vaccination side effects such as lymphadenopathy (LAP) were observed. The present study reviewed all studies with imaging findings presentation of LAP after COVID-19 vaccination.

Materials And Methods: We conducted a literature search in online databases, including Scopus, Medline (PubMed), Web of Science, Embase (Elsevier), Cochrane library, and Google Scholar.

Coronavirus disease 2019 (COVID-19): A systematic review of 133 Children that presented with Kawasaki-like multisystem inflammatory syndrome.

Kawasaki-like disease (KLD) and multisystem inflammatory syndrome in children (MIS-C) are considered as challenges for pediatric patients under the age of 18 infected with coronavirus disease 2019 (COVID-19). A systematic search was performed on July 2, 2020, and updated on December 1, 2020, to identify studies on KLD/MIS-C associated with COVID-19. The databases of Scopus, PubMed, Web of Science, Embase, and Scholar were searched.

Image-Guided Percutaneous Pancreatic Duct Drainage: A 10-Year Observational Study.

Purpose: To study the safety, efficacy, and long-term outcomes of percutaneous pancreatic duct drainage (PPDD) for treating pancreatic duct (PD) obstruction.

Materials And Methods: This prospective observational cohort study included 73 patients with PD obstruction between December 2010 and June 2020. Patients underwent PPDD under ultrasound and fluoroscopy guidance, computed tomography (CT) and fluoroscopy guidance, or CT guidance only.

Left gastric artery embolization for obesity treatment: a systematic review and meta-analysis of human and animal studies.

Purpose: The main purpose of this systematic review was to reflect on recent literature on bariatric LGA embolization for obesity treatment and to compare this new procedure in human and animal studies.

Methods: A systematic search of Scopus, MEDLINE, Web of Science, Embase, and Google Scholar was performed to identify human and animal studies employing bariatric LGA embolization to treat obesity. As well, Cochrane's Q test and the I statistic were utilized to determine heterogeneity.

Pelvic Pain and Adnexal Mass: Be Aware of Accessory and Cavitated Uterine Mass.

Accessory and cavitated uterine mass (ACUM) is a rare form of Mullerian anomaly that usually presents in young females with chronic cyclic pelvic pain and/or dysmenorrhea. This clinical entity is often underdiagnosed as it may be mistaken for other differential diagnoses, such as pedunculated myoma or adnexal lesions. Imaging modalities, including ultrasonography and magnetic resonance imaging (MRI), accompanied with relevant and suspicious clinical findings are important tools in making acorrect diagnosis.

MODERN METHODS IN OTORHINOLARYNGOLOGY: POWERED-SHAVER ADENOIDECTOMY.

Endoscopic adenoidectomy with shaver is a safe, precise and fast procedure with minimal blood loss. With the help of this method, adenoids are completely removed without damage to adjacent tissues. Use of endoscope provides the possibility to display the operation on the screen in enlarged format and if applicable, the operation may be recorded.

Cured giant hepatocellular carcinoma after transarterial embolization complicated with liver abscess formation.

Many patients with hepatocellular carcinoma cannot be treated surgically because of the advanced stage of the tumor and/or coexisting cirrhosis. Transcatheter arterial embolization (TAE) represents an alternative therapeutic approach for some of these patients. However, it is not a curative measure, and an additional therapy is required to eradicate the residual disease.

[OPPORTUNITIES OF ULTRASOUND IMAGING FOR VISUALIZATION OF THE SHOULDER JOINT PATHOLOGICAL CHANGES].

Aim of investigation - the assessment of opportunities of ultrasound (US) imaging for visualization of the shoulder joint pathological changes. 100 patients with the pathologies of shoulder joint have been investigated, they included traumatic, degenerative -dystrophic and inflammatory pathologies (tendinitis, tendinosis, tendinopathy, subacromial-subdelatoid bursitis).Ultrasound study performed on ultrasound TOSHIBA xario XG by high linear probe (7,5-12.

THE SERUM LEVELS OF ANTI-MÜLLERIAN HORMONE BEFORE AND AFTER ENUCLEATION OF THE ENDOMETRIOID CYST.

There is a controvercy in the scientific literature concerning the benefits of the enucleation of the endometroid cysts with respect to the treatment of infertility in ednometrioma sufferers. Some authors claim, that the laparoscopic surgical intervention leads to the reduction of the ovarian reserve. In particular, authors report on the decrease in the level of the serum anti-Müllerian hormone (AMH) after surgical intervention.

USING OF NOVEL DOUBLE INVAGINATED PANCREATOJEJUNOSTOMY TECHNIQUE WITH TRANSANASTOMOTIC STENTING AND EXTERNAL PANCREATIC DUCT DRAINAGE: PRELIMINARY REPORT.

Following the pancreatoduodenectomy the pancreatic anastomosis, which is still "Achilles" heel of pancreatic surgery, carries the highest risk of leak and cause of morbidity and mortality. More than 80 different methods of reconstruction have been proposed, illustrating the complexity of surgical techniques as well as the absence of the "ideal" pancreatic anastomosis and gold standard up to date. Here, we describe the novel method of double invaginated pancreatojejunostomy with transanastomotic stent and external pancreatic duct drainage.