831 results match your criteria: ""Kore" University of Enna.[Affiliation]"

[This corrects the article DOI: 10.1055/a-2303-8621.].

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Smoking habits (from classic cigarettes to e-cigarettes and heated tobacco) are a relatively common finding in the medical histories of couples referred to fertility centers. Tobacco smoke and e-cigarettes may deliver many substances with known harmful effects on both general and reproductive health, including nicotine. Nicotinic Acetylcholine receptors (nAChRs) form a heterogeneous family of ion channels that are differently expressed in different tissues.

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Oral Health and Nutraceutical Agents.

Int J Mol Sci

September 2024

Department of Promotion of Human Sciences and Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.

Oral health is essential for both overall health and quality of life. The mouth is a window into the body's health, and nutrition can strongly impact the state of general and oral health. A healthy diet involves the synergistic effect of various nutraceutical agents, potentially capable of conferring protective actions against some inflammatory and chronic-degenerative disorders.

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New Insights into Adipose Tissue Metabolic Function and Dysfunction, 2nd Edition.

Int J Mol Sci

August 2024

Department of Medicine and Surgery, University of Enna "Kore", Contrada Santa Panasia, 94100 Enna, Italy.

The adipose organ is well recognized for its role in energy storage and mobilization, responding to nutrient availability, the body's needs, and thermogenesis, thereby regulating the organism's energy balance [...

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(1) Background: Ocular emergencies account for 1.5-3% of emergency department (ED) visits and require urgent diagnosis to prevent serious complications. Ultrasonography is a crucial, non-invasive diagnostic tool for these conditions but traditionally lacks portability and integration with modern electronic smart devices.

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Consumption of high-fat diets (HFDs) is a contributing factor to obesity, insulin resistance and non-alcoholic fatty liver disease (NAFLD). Several studies suggested the protective role of bioactives present in fruits against the above mentioned chronic metabolic conditions. In this study, we evaluated if a flavonoid-rich extract of (bergamot) juice (BJe) could inhibit HFD-induced intestinal permeability and endotoxemia and, through this mechanism, mitigate the associated hepatic damage in C57BL/6J mice.

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Article Synopsis
  • - Age-related macular degeneration (AMD) is a major cause of vision loss in older adults, and currently, there are no effective drugs to treat it.
  • - Research is exploring the use of stem cells to replace damaged retinal cells, specifically targeting retinal pigment epithelium (RPE) for potential therapy.
  • - This chapter reviews key clinical trials and protocols on using stem cell therapy for AMD, detailing how the progression of the disease and treatment responses have been monitored.
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Glioblastoma (GBM) represents an aggressive brain tumor, characterized by intra- and inter-tumoral heterogeneity and therapy resistance, leading to unfavourable prognosis. An increasing number of studies pays attention on the regulation of ferroptosis, an iron-dependent cell death, as a strategy to reverse drug resistance in cancer. However, the debate on whether this strategy may have important implications for the treatment of GBM is still ongoing.

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An association between type 2 diabetes (T2D) and breast cancer risk has been reported. This association can be potentially explained by alteration of the insulin/IGF system. Therefore, we aimed to prospectively investigate whether a previously reported Dietary-Based Diabetes Risk Score (DDS) inversely associated with T2D was also associated with breast cancer risk in the SUN ("Seguimiento Universidad de Navarra") cohort.

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Emerging occupational risks in green jobs: a review.

Int J Occup Med Environ Health

September 2024

University of Palermo, Palermo, Italy (Internal Medicine and Medical Specialties "Giuseppe D'Alessandro", Department of Health Promotion, Sciences Maternal and Child Care).

Green jobs are to be understood as those jobs directly associated with specific sustainability issues and activities related to the efficiency, quality and innovation of goods and services offered, from an eco-sustainability perspective. The objective of the research was to fill knowledge gaps of new and emerging environmental and occupational risks related to sustainable activities and to understand the impact these might have on workers' psychological and physical well-being. A selection of several scientific articles and a critical analysis of the selected articles was carried out from the perspective of defining the concept of "emerging occupational risks in green jobs," using different keywords in the title or abstract as search criteria.

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Vaccination, particularly against pneumococcus and influenza, is a low-cost primary prevention, useful to avoid hard complications, particularly among frail older people. In this pilot study, we aimed to assess the effect of a strategy for influenza and pneumococcal vaccination for outpatients mainly affected by cognitive or endocrinological conditions, evaluating what could stimulate or demotivate vaccination among older people. This study was conducted during the 2023-2024 influenza season at the outpatient clinics in Palermo, Italy.

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Article Synopsis
  • * The authors conducted a literature search that yielded 21 relevant studies from PubMed, focusing on the characteristics of the ocular surface and the microbiome's role in glaucoma.
  • * Key topics discussed include the anatomy of the eye, the effects of microbial imbalance (dysbiosis), immune responses, and future treatment strategies that could benefit ocular health by targeting the microbiome.
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Fish oil, renowned for its high content of omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has gained considerable attention for its potential health benefits. EPA and DHA exhibit anti-inflammatory effects by promoting the production of specialized pro-resolving mediators (SPMs), such as resolvins and protectins. Fish oil has been studied for its potential to reduce bronchial inflammation, a key feature of respiratory conditions like asthma and COPD.

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Obesity is considered one of the main risk factors for cardiovascular diseases. The browning process has been recently recognized as a promising anti-obesity therapy. Lycopene (LYC) and fruit extract (GE) might be important resources for anti-obesity drugs; therefore, the aim of this study was to investigate the anti-obesity effects of LYC and GE on 3T3-L1 adipocytes and Zucker rats.

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Vitamin D3 is a crucial fat-soluble pro-hormone essential for bolstering bone health and fortifying immune responses within the human body. Orodispersible films (ODFs) serve as a noteworthy formulation strategically designed to enhance the rapid dissolution of vitamin D, thereby facilitating efficient absorption in patients. This innovative approach not only streamlines the assimilation process but also plays a pivotal role in optimizing patient compliance and therapeutic outcomes.

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Article Synopsis
  • * A study analyzed data from 24 deceased donor uterus transplants, finding a significant birth rate of 66%, but also a 25% rate of graft loss over time, encompassing various countries with differing success rates.
  • * The majority of recipients had MRKH syndrome, with median ages of 29.8 for recipients and 36.1 for donors; ethical concerns may be less complex for deceased donor transplants compared to living ones, highlighting the
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  • The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has impacted not only the respiratory system but also various eye-related conditions, demonstrating a range of ocular symptoms.
  • Important eye manifestations of COVID-19 include conjunctivitis, scleritis, uveitis, and retinopathy, making it crucial for eye care practitioners to monitor these signs as potential early indicators of the disease.
  • The review also discusses how the virus interacts with ocular tissues and examines vaccine-related ocular side effects, highlighting the necessity for continued research on vaccine safety and effective eye examinations for COVID-19 patients.
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Proliferative vitreoretinopathy (PVR) has traditionally been managed with vitreoretinal surgery. Although there have been several recent innovations in this surgery to make the retinal approach as uninvasive as possible, the outcomes remain unsatisfactory. Significant complications remain and the complexity of the surgical approach is challenging.

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: Patients treated with definitive radiotherapy for nasopharyngeal carcinoma (NPC) develop severe dysphagia, affecting their quality of life. Traditional prognosis biomarkers are insufficient, leading to a search for new predictors like neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR). : We retrospectively enrolled 44 NPC patients who underwent definitive radiotherapy between 2010 and 2018.

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  • Lentigo maligna (LM) and lentigo maligna melanoma (LMM) are key melanoma subtypes with an incidence of 1.37 per 100,000 in the U.S., often misdiagnosed, especially among the elderly, leading to treatment delays.
  • A study evaluated the diagnostic abilities of ophthalmologists in identifying pigmented skin lesions in the periorbital region by reviewing 79 cases, comparing their results with dermatologists.
  • Results showed that ophthalmologists had a diagnostic accuracy of 63.5% and lower sensitivity compared to dermatologists (33.3% vs. 46.9%), with a significantly higher percentage of ophthalmologists rating cases as "difficult" and suggesting fewer biopsies
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