Post-implant transcatheter aortic prosthesis deformation: tricuspid versus bicuspid valve.

Objectives: We sought to assess whether post-implant transcatheter aortic valve prosthesis multidetector computed characteristics differ between patients with native tricuspid and bicuspid aortic valve stenosis, as well as the effect on valve performance and clinical implications.

Methods: We analysed 100 consecutive post-implant multidetector computed tomography scans to assess self-expandable prosthesis non-uniform expansion at 6 pre-specified valvular levels, and other specific parameters, including valvular and perivalvular thrombosis at 6 months follow-up. Echocardiographic prosthesis performance and clinical outcome were also evaluated.

Remediation of a diesel contaminated soil by means of anionic and non-ionic surfactants: Effect on soil phosphorus availability and Vicia Faba L. growth.

In the present study, the effectiveness of two surfactants (Polysorbate 80 - Tween 80 and Sodium Dodecyl Benzensulphonate - SDBS) was investigated for the remediation of a hydrocarbon-contaminated soil. Moreover, it was elucidated the impact of surfactants on soil phosphorus (P) availability and phytotoxic effect on the growth of Vicia Faba L. An experimental laboratory-scale apparatus (bench and pilot scale) was set up for the simulation of a soil flushing intervention.

CFD study on the effect of the baffles geometry in sedimentation efficiency in wastewater treatments through Large Eddy Simulations.

Sedimentation tanks represent one of the most important components of any water and wastewater treatment plants. The lack of knowledge of hydraulics in sedimentation tank leads to unnecessary capital and operating costs as well as water pollution in the form of excessive sludge. Improper and inadequate design cause overloading of filters, and lead to frequent backwashing, which in turn waste a significant percentage of treated water.

Management of Eyelid Pathologies That Cause Corneal Lesions.

Corneal injuries, which make up 3% of emergency room visits, can vary from small scratches to exposure or trauma-related damage that might be fatal to vision. Mechanical trauma, diseases of the eyelids, neurotrophic abnormalities, and chemical burns are common causes. A thorough examination is necessary for an accurate diagnosis and treatment plan.

The revival of psilocybin between scientific excitement, evidence of efficacy, and real-world challenges.

The revival of psilocybin in psychopharmacological research heralds a potential paradigm shift for treating mood and anxiety disorders, and other psychiatric conditions beyond the psychotic spectrum. This critical review evaluates current evidence on psilocybin's efficacy, juxtaposing potential benefits with the practical aspects of psychedelic-assisted psychotherapy (PAP) and the methodological constraints of existing research.An electronic literature search was conducted using PubMed/MEDLINE, selecting studies published up to December 2023 that explored the clinical use of psilocybin in mood and anxiety disorders, obsessive-compulsive disorder, post-traumatic stress disorder, and substance use disorder.

Enabling personalized smart tourism with location-based social networks.

With the rapid advance of mobile internet, communication technology and the Internet of Things (IoT), the tourism industry is undergoing unprecedented transformation. Smart tourism offers users personalized and customized services for travel planning and recommendations. Location-based social networks (LBSNs) play a crucial role in smart tourism industry by providing abundant data sources through their social networking attributes.

Investigating the plasma electrophoretic protein profile of kids and lambs during the neonatal period: An overview of their immuno-inflammatory status.

The study aimed to evaluate how plasma total proteins, their fractions (i.e. albumin, α1-, β-, γ-globulins) and A/G ratio change in lambs and kids over the first month of life.

The microbiome-driven impact of western diet in the development of noncommunicable chronic disorders.

Noncommunicable chronic disorders (NCDs) are multifactorial disorders that share a state of chronic, low-grade inflammation together with an imbalance of gut microbiota. NCDs are becoming increasingly prevalent worldwide, and mainly in Western countries, with a significant impact on global health. Societal changes, together with the widespread diffusion of modern agricultural methods and food processing, have led to a significant shift in dietary habits over the past century, with an increased diffusion of the Western diet (WD).

Impact of neck dissection in cN0 patients undergoing primary or salvage total laryngectomy.

Introduction: It is debatable whether neck dissection is necessary in patients with advanced laryngeal carcinoma who are clinically node-negative (cN0). We assessed the effect of neck dissection on overall survival in patients with cN0 undergoing primary or salvage laryngectomy.

Materials And Methods: A retrospective evaluation of cN0 patients who underwent primary or salvage total/pharyngolaryngectomy at a French tertiary facility in 2008-2018, with or without neck dissection, was carried out.

Differences in emotion recognition between nonimmersive versus immersive virtual reality: preliminary findings in schizophrenia and bipolar disorder.

Deficits in social cognition may impair emotional processing and facial emotional recognition (FER) in patients with bipolar disorder (BD) and schizophrenia. FER is generally explored using photographs or images of static faces that do not fully capture the complexity of real-life facial stimuli. To overcome this limitation, we developed a set of dynamic virtual faces depicting six basic emotions (i.

Mediterranean diet and osteoarthritis: an update.

The Mediterranean diet has gained significant attention for its potential health benefits on diverse pathological conditions including osteoarthritis (OA), a prevalent degenerative joint disease characterized by cartilage breakdown and inflammation. Numerous observational studies have suggested that adherence to the Mediterranean diet, may have protective effects against OA. The abundance of antioxidants and anti-inflammatory compounds and omega-3 fatty acids, among the Mediterranean diet components is believed to contribute to its beneficial effects on OA.

Circadian clock disruption impairs immune oscillation in chronic endogenous hypercortisolism: a multi-level analysis from a multicentre clinical trial.

Background: Glucocorticoids (GC) are potent entrainers of the circadian clock. However, their effects on biological rhythms in chronic human exposure have yet to be studied. Endogenous hypercortisolism (Cushing's Syndrome, CS) is a rare condition in which circadian disruption is sustained by a tumorous source of GC excess, offering the unique opportunity to investigate GC's chronic effects in vivo.

From active escapism to virtual withdrawal: Validation of the Compensatory-Dissociative Online Gaming scales (C-DOGs).

Background: In the Compensatory-Dissociative Online Gaming (C-DOG; Giardina et al., 2024) model, we proposed a continuum from compensatory to dissociative gaming involvement. This continuum represents different degrees of integration between physical and virtual environments with three core processes - Active Escapism, Escape, and Dissociation - and two peripheral processes - Gaming-Related Relaxation and Body-Mind Detachment.

Microgravity Effects on Glioma Cells: A Comprehensive Review.

High-grade gliomas (HGGs) represent a formidable challenge in neuro-oncology due to their aggressive nature and resistance to current therapeutic interventions, which include surgery, radiation, chemotherapy, and emerging immunotherapies. Despite these efforts, the prognosis for patients remains poor, emphasizing the urgent need for novel treatment strategies. One promising avenue of exploration is microgravity, a condition experienced during spaceflight and simulated in laboratories on Earth, which induces significant physiological changes in cells and tissues.

A Snapshot of Vitamin D Status, Performance, Blood Markers, and Dietary Habits in Runners and Non-Runners.

Background: Vitamin D can influence athletic performance and infection risk. This study aimed to investigate vitamin D status, hematochemical factors, anthropometric and performance parameters, and dietary habits in runners (n = 23) and sedentary healthy individuals (non-runners, n = 22) during the autumn season.

Methods: Both groups had their serum 25-Hydroxyvitamin D (ng/mL) levels, blood and performance parameters, and dietary habits measured.

Novel Approaches for the Early Detection of Glaucoma Using Artificial Intelligence.

Background: If left untreated, glaucoma-the second most common cause of blindness worldwide-causes irreversible visual loss due to a gradual neurodegeneration of the retinal ganglion cells. Conventional techniques for identifying glaucoma, like optical coherence tomography (OCT) and visual field exams, are frequently laborious and dependent on subjective interpretation. Through the fast and accurate analysis of massive amounts of imaging data, artificial intelligence (AI), in particular machine learning (ML) and deep learning (DL), has emerged as a promising method to improve the early detection and management of glaucoma.

Identification of Predictors of Sarcopenia in Older Adults Using Machine Learning: English Longitudinal Study of Ageing.

After its introduction in the ICD-10-CM in 2016, sarcopenia is a condition widely considered to be a medical disease with important consequences for the elderly. Considering its high prevalence in older adults and its detrimental effects on health, it is essential to identify its risk factors to inform targeted interventions. Taking data from wave 2 of the ELSA, using ML-based methods, this study investigates which factors are significantly associated with sarcopenia.