1 results match your criteria: ""Gr. T. Popa" University of Medicine and Pharmacy - Pathology[Affiliation]"
INSIGHTS ON AROMATASE IMMUNOHISTOCHEMISTRY: VARIATIONS BETWEEN INTRINSIC MOLECULAR SUBTYPES OF BREAST CANCERS.
Acta Endocrinol (Buchar)
January 2020
"Gr. T. Popa" University of Medicine and Pharmacy - Pathology, Iasi, Romania.
Context: Aromatase is a key enzyme in local estrogen production by androgen conversion, especially in women post-menopause. There have been controversies concerning aromatase localization in breast carcinomas and its association with current histopathological variables.
Material And Methods: Using polyclonal antibody immunohistochemistry we assessed (by intensity and percentage scores) the immunolocalization of aromatase in 70 tissue samples, and described particularities within the molecular subtypes of breast cancer.