770 results match your criteria: ""Gheorghe Asachi" Technical University[Affiliation]"
Microsc Res Tech
January 2025
Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania.
One area of technological advancement has been the shift from stainless steel hand tools to nickel-titanium (Ni-Ti) rotary tools. This paper aims to perform an in vitro comparative study to evaluate the efficacy of five endodontic manual and rotary instruments such as Kerr files, Orodeka Plex V, ProTaper Flydent NiTi super files, and ProTaper Flydent NiTi super files in combination with an ultrasonic endodontic E3D Diamantata EMS scaler used for root canal shaping. The following aspects were highlighted: effective removal of smear layer (SL) from the dentinal tubules in the coronal 1/3, middle 1/3, and apical 1/3 of the root canal, appearance of cracks in the dentinal walls by SEM analysis, and highlighting of dentin mineral content and remnant debris by EDX analysis.
View Article and Find Full Text PDFPharmaceutics
January 2025
Faculty of Pharmacy, "Grigore. T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Magnolol (MG) and honokiol (HK) are bioactive compounds extracted from and trees with significant pharmacological properties, including antioxidant and antibacterial activity. However, their poor water solubility and low bioavailability limit the therapeutic potential. To address these limitations, this study aims to develop MG and HK formulations by co-electrospinning using custom-synthesized β-cyclodextrin-oligolactide (β-CDLA) derivatives.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Faculty of Mechanics, University Politehnica of Timisoara, Piata Victoriei 2, 300006 Timisoara, Romania.
This study investigated silicone composites with distributed boron nitride platelets and carbon microfibers that are oriented electrically. The process involved homogenizing and dispersing nano/microparticles in the liquid polymer, aligning the particles with DC and AC electric fields, and curing the composite with IR radiation to trap particles within chains. This innovative concept utilized two fields to align particles, improving the even distribution of carbon microfibers among BN in the chains.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2025
Department of Pharmaceutical Botany, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
The present experiment aimed to formulate four ointments that included mixtures of plant extracts (, , , and ), apitherapy products (honey, propolis, and apilarnil) and natural polymers (collagen, chitosan, and the lyophilisate of egg white) in an ointment base. : In order to investigate the therapeutic properties of the ointments, experimental in vivo injury models (linear incision, circular excision, and thermal burns) were performed on laboratory animals, namely Wistar rats. The treatment was applied topically, once a day, for 21 days.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Faculty of Materials Science and Engineering, "Gheorghe Asachi" Technical University of Iasi, 67 Dimitrie Mangeron Street, 700050 Iasi, Romania.
The high yttria content of a stabilized zirconia (YSZ) (38 wt% YO) coating was deposited by atmospheric plasma spraying (APS) from Metco 207 powders on an Inconel 718 (Ni-based superalloy) substrate. As a metal coating connection, a layer of cermet powder (Ni-20% Al-410NS) was used before the ceramic layer deposition. The electro-chemical corrosion resistance of these materials was tested using Inconel cylinders with a diameter of 10 mm and a thickness of 1 mm, with and without the ceramic layer.
View Article and Find Full Text PDFMicroorganisms
January 2025
Department of Molecular Environmental Biotechnology, Helmholtz Centre for Environmental Research-UFZ, 04318 Leipzig, Germany.
Although bioremediation is considered the most environmentally friendly and sustainable technique for remediating contaminated soil and water, it is most effective when combined with physicochemical methods, which allow for the preliminary removal of large quantities of pollutants. This allows microorganisms to efficiently eliminate the remaining contaminants. In addition to requiring the necessary genes and degradation pathways for specific substrates, as well as tolerance to adverse environmental conditions, microorganisms may perform below expectations.
View Article and Find Full Text PDFMicromachines (Basel)
January 2025
Department of Machine Manufacturing Technology, "Gheorghe Asachi" Technical University of Iasi, 700050 Iasi, Romania.
This manuscript highlights the behavior of biodegradable polymers (PLA and HD PLA Green) coated with two distinct bronze alloy powders, Metco 51F-NS (Cu 9.5Al 1.2Fe) and Metco 445 (Cu 9.
View Article and Find Full Text PDFPharmaceutics
December 2024
Department of Physico-Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, Romania.
Diabetes is a growing global health crisis that requires effective therapeutic strategies to optimize treatment outcomes. This study aims to address this challenge by developing and characterizing extended-release polymeric matrix tablets containing metformin hydrochloride (M-HCl), a first-line treatment for type 2 diabetes, and honokiol (HNK), a bioactive compound with potential therapeutic benefits. The objective is to enhance glycemic control and overall therapeutic outcomes through an innovative dual-drug delivery system.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Faculty of Materials Science and Engineering, "Gheorghe Asachi" Technical University of Iași, Blvd. Dimitrie Mangeron 71A, 700050 Iasi, Romania.
The paper starts by describing the manufacturing process of cups thermoformed from extruded foils of 80% recycled PET (80r-PET), which comprises heating, hot deep drawing and cooling. The 80r-PET foils were heated up to 120 °C, at heating rates of the order of hundreds °C/min, and deep drawn with multiple punchers, having a depth-to-width ratio exceeding 1:1. After puncher-assisted deformation, the cups were air blown away from the punchers, thus being "frozen" in the deformed state.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Department of Electrical Measurements and Materials, Gheorghe Asachi Technical University, Boulevard D. Mangeron 71, 700050 Iasi, Romania.
This study investigated the creation of nano-composites using recycled LDPE and added 7.5 wt% nanofillers of Al and Fe in two varying particle sizes to be used as hot-melt adhesives for reversible bonding processes with the use of microwave technology. Reversible bonding relates to circular economy enhancement practices, like repair, refurbishment, replacement, or renovation.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
Department of Material Engineering, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
This manuscript contributes to understanding the role of hydrogen in different materials, emphasizing polymers and composite materials, to increase hydrogen storage capacity in those materials. Hydrogen storage is critical in advancing and optimizing sustainable energy solutions that are essential for improving their performance. Capillary arrays, which offer increased surface area and optimized storage geometries, present a promising avenue for enhancing hydrogen uptake.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Faculty of Dental Medicine, "Dunarea de Jos" University, Al. I. Cuza Street 35, 800216 Galati, Romania.
: This study aimed to evaluate the role of A-PRF (advanced platelet-rich fibrin) in the enhancement of wound healing and protecting the periodontal health of mandibular second molars after the extraction of mandibular third molars. Additionally, the study assessed the levels of pro-inflammatory cytokines in the gingival crevicular fluid (GCF) of mandibular second molars as markers of inflammation. : Twenty-five systemically healthy adult patients with bilateral removal of impacted mandibular third molars were included.
View Article and Find Full Text PDFLife (Basel)
December 2024
Department of Orthopedics and Traumatology, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Objective: This study aims to evaluate and compare the biomechanical performance of two Kirschner (K) wire configurations-the intra-focal and interfragmentary techniques-for the fixation of dorsally displaced distal radius fractures. The study also assesses the impact of K-wire diameter (1.6 mm vs.
View Article and Find Full Text PDFBiomedicines
December 2024
Department of Pharmaceutical Technology, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.
: This study explored the potential of MCM-48 mesoporous silica matrices as a drug delivery system for metformin hydrochloride, aimed at improving the therapeutic management of type 2 diabetes mellitus. The objectives included the synthesis and characterization of MCM-48, assessment of its drug loading capacity, analysis of drug release profiles under simulated physiological conditions, and the development of a multifractal dynamics-based theoretical framework to model and interpret the release kinetics. : MCM-48 was synthesized using a sol-gel method and characterized by SEM-EDX, TEM, and nitrogen adsorption techniques.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
Faculty of Industrial Design and Business Management, "Gheorghe Asachi" Technical University of Iași, 700050 Iasi, Romania.
Background/objectives: Moral hazard represents a significant challenge in healthcare systems globally, reflecting the tendency of insured individuals to over-utilize medical services when shielded from the full costs of care.
Methods: This paper investigates the dynamics and implications of moral hazard within the Romanian public hospital sector, offering practical recommendations for healthcare policymakers to mitigate the financial risks associated with excessive healthcare utilization and ensure long-term sustainability. To achieve the objectives of this study, a quantitative research approach utilizing vignettes was employed.
Gels
December 2024
"Ion Ionescu de la Brad" Iasi University of Life Sciences, 3 Mihail Sadoveanu Alley, 700490 Iasi, Romania.
This paper provides a solid foundation for understanding the synthesis, properties, and applications of cellulose-based gels. It effectively showcases the potential of these gels in diverse applications, particularly in biomedicine, and highlights key synthesis methods and properties. However, to push the field forward, future research should address the gaps in understanding the environmental impact, mechanical stability, and scalability of cellulose-based gels, while also considering how to overcome barriers to their industrial use.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Faculty of Electronics, Telecommunications and Information Technology, Gheorghe Asachi Technical University of Iaşi, 700506 Iaşi, Romania.
In this work, an analytical method in the frequency domain is proposed for the design of two-dimensional digital FIR differentiators. This technique uses an approximation based on two methods: the Chebyshev series and the Fourier series, which, finally, lead to a trigonometric polynomial, which is a remarkably precise approximation of the transfer function of the ideal differentiator. The digital differentiator is applied to three test images, one greyscale image and two binary images, and simulation results show its performance in the processing task.
View Article and Find Full Text PDFHealthcare (Basel)
November 2024
School of Engineering Technology and Applied Science, Centennial College, 941 Progress Ave., Scarborough, ON M1G 3T8, Canada.
Background/objectives: Our study investigates the primary characteristics of managerial decision-making processes in the public hospital units in Romania, particularly in the Northeast region. This research aims to delineate the decision-making model applied by managers in these units, considering the multitude of legislative, economic, technical, ethical, and organizational changes prompted by the pandemic.
Methods: A mixed-method research approach was utilized, combining semi-structured interviews and autoethnography, to capture experiences, attitudes, perceptions, motivations, and ethical considerations of decision-makers within the healthcare system.
Polymers (Basel)
December 2024
Faculty of Industrial Design and Business Management, "Gheorghe Asachi" Technical University of Iasi, 29 Prof. Dr. Doc. D. Mangeron Blvd, 700050 Iasi, Romania.
Increasing environmental awareness has boosted interest in sustainable alternatives for binding natural reinforcing fibers in composites. Utilizing lignin, a biorenewable polymer byproduct from several industries, as a component in polymer matrices can lead to the development of more eco-friendly and high-performance composite materials. This research work aimed to investigate the effect of two types of lignin (lignosulfonate and soda lignin) on the properties of hemp fiber-reinforced polypropylene composites for furniture applications.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Department of Communications, Faculty of Electronics, Telecommunications and Information Technologies, "Politehnica" University of Timisoara, V. Pârvan Blvd., No. 2, 300223 Timisoara, Romania.
Supercapacitor/pseudocapacitor structures with electrodes and electrolytes based on conductive polymers, but not only, have been analyzed using techniques. Results indicated in the literature were used to confirm the results obtained for the specific capacitance and energetic performances of the systems. New material classes like Polymer-MXene electrodes ((PANI)/TiC, PFDs/TiCT) present increased capacitance in comparison with simple polymeric composites (PETC or PTh).
View Article and Find Full Text PDFCancers (Basel)
November 2024
Department of Electrical Measurements and Materials, Gheorghe Asachi Technical University, 700050 Iasi, Romania.
Colorectal cancer (CRC) remains a significant global health burden, necessitating a thorough understanding of prognostic and predictive factors to enhance patient outcomes. This systematic review aims to comprehensively evaluate prognostic and predictive determinants in CRC, encompassing both traditional and emerging biomarkers. A systematic search of major electronic databases was conducted to identify relevant studies published from 1995 up to 2024.
View Article and Find Full Text PDFChemosphere
February 2025
Department of Chemistry, Soongsil University, Seoul, 06978, South Korea; Department of Sustainable Engineering, Saveetha School of Engineering, SIMATS, Chennai, 602105, India; Department of Chemical Engineering, Quchan University of Technology, Quchan, Iran.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal).
View Article and Find Full Text PDFNutrients
November 2024
Department of Mother and Child, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Background: Vitamin D plays an important role in maintaining bone health with numerous benefits for extraskeletal health as well.
Objectives: We aimed to assess the prevalence of vitamin D deficiency in children (0-18 years old) in a tertiary hospital in Romania between August 2019 and January 2024 and to investigate the role of adequate supplementation in this vulnerable population.
Methods: The serum 25(OH)D levels were measured using a chemiluminescence binding assay.
Polymers (Basel)
November 2024
Department of Nutrition and Dietetics, Faculty of Pharmacy, Vasile Goldis Western University of Arad, Liviu Rebreanu Street, 86, 310045 Arad, Romania.
The main goal of this research was to create biocompatible hydrogels using gelatin and a double cross-linking technique involving both covalent and ionic bonds to immobilize propolis. The covalent bonds were formed through Schiff base cross-links between protein-free amino groups (NH) from the lysine residue and aldehyde groups (CHO) produced by oxidizing sodium alginate with NaIO, while the ionic bonds were achieved using Mg ions. Hydrogel films were obtained by varying the molar ratios of -CHO/-NH under different pH conditions (3.
View Article and Find Full Text PDFPolymers (Basel)
November 2024
Faculty of Industrial Design and Business Management, "Gheorghe Asachi" Technical University of Iasi, 29 Prof. Dr. Doc. D. Mangeron Blvd, 700050 Iasi, Romania.