217 results match your criteria: ""GB. Morgagni" Hospital[Affiliation]"
Expert Rev Respir Med
January 2025
Department of Anesthesia and Intensive Care, Fondazione Istituto "G. Giglio" Cefalù, Cefalù, Italy.
Introduction: To evaluate the effectiveness of noninvasive positive pressure ventilation (NPPV) versus standard therapy in severe asthma exacerbations through meta-analysis.
Methods: Nine randomized controlled trials (344 patients) were analyzed from inception to August 2024. Primary outcomes included respiratory rate, forced expiratory volume in first second (FEV1), and oxygen saturation (SpO2).
J Rheumatol
January 2025
Florenzo Iannone, Rheumatology Unit - Department of Precision and Regenerative Medicine of Jonian Area University of Bari, Bari, Italy.
Objective: Bosentan (BOS) is approved for treating pulmonary arterial hypertension (PAH) and preventing digital ulcers (DU) in systemic sclerosis (SSc). Our study aimed to evaluate whether BOS prescribed for DU could reduce the incidence of PAH in a large SSc cohort from the SPRING registry.
Methods: Patients with SSc from the SPRING registry, meeting ACR/EULAR 2013 classification criteria with data on PAH onset, DU status, BOS exposure, and at least a one-year follow-up between 2015 and 2020, and no known PAH at baseline were included.
Thorax
December 2024
Department of Medical Specialities, Pulmonology Unit, GB Morgagni-L. Pierantoni Hospital, Forlì, Italy
Eur J Heart Fail
December 2024
Kore University, Enna and Policlinico Centro Cuore GB Morgagni, Catania, Italy.
Aims: Left ventricular unloading by percutaneous microaxial flow-pump devices has been shown to improve survival in patients with cardiogenic shock (CS). The objective of the study is to examine whether Impella 5.0/5.
View Article and Find Full Text PDFAm J Respir Crit Care Med
November 2024
GB MORGAGNI HOSPITAL, INTERVENTIONAL PNEUMOLOGY, FORLì, FC, Italy.
J Clin Med
October 2024
Faculty of Medicine and Surgery, Kore University, 94100 Enna, Italy.
This comprehensive review examines the role of Fenoldopam, a selective dopamine-1 receptor agonist, in preventing and treating acute kidney injury (AKI) during cardiac surgery. AKI remains a significant complication in cardiac surgery, associated with increased morbidity, mortality, and healthcare costs. The review explores Fenoldopam's pharmacological properties, mechanism of action, and clinical applications, synthesizing evidence from randomized controlled trials, meta-analyses, and observational studies.
View Article and Find Full Text PDFSarcoidosis Vasc Diffuse Lung Dis
September 2024
Department of Diseases of the Thorax, Ospedale GB Morgagni, University of Bologna, Italy and Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Denmark.
J Otolaryngol Head Neck Surg
September 2024
Otolaryngology, Western University, London, ON, Canada.
Objective.: A new critical complication risk analysis, the reasonable risk ratio (RRR or R) for palate surgeries in obstructive sleep apnea patients.
Methods.
Pulmonology
September 2024
Department of Medical Specialities/Pulmonology Ospedale GB Morgagni, Forlì (I); DIMEC, Bologna University, Forlì Campus, Forlì I, Department; Department of Respiratory Diseases & Allergy, Aarhus University, Aarhus, Denmark.
J Thorac Dis
August 2024
Department of Anesthesiology, Critical Care Medicine and Emergency, SS. Annunziata Hospital, Chieti, Italy.
J Cardiothorac Vasc Anesth
December 2024
Adult Intensive Care, Royal Brompton and Harefield Guy's & St. Thomas' NHS Foundation Trust, London, UK.
Evaluation of treatment outcomes in patients supported by temporary mechanical circulatory support (tMCS) currently relies mainly on mortality, which may not sufficiently address other patient benefits or harms. Bleeding and thrombosis are major contributors to mortality. Still, current bleeding scores are not designed for critically ill patients undergoing tMCS, only consider selected populations, and do not account for the high heterogeneity among bleeding and thrombotic adverse events.
View Article and Find Full Text PDFHistopathology
January 2025
Department of Pathology, St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Aim: Transbronchial cryobiopsies are increasingly used for the diagnosis of interstitial lung disease (ILD), but there is a lack of published information on the features of specific ILD in cryobiopsies. Here we attempt to provide pathological guidelines for separating usual interstitial pneumonia (UIP) of idiopathic pulmonary fibrosis (IPF), fibrotic hypersensitivity pneumonitis (FHP) and connective tissue disease-associated ILD (CTD-ILD) in cryobiopsies.
Methods: We examined 120 cryobiopsies from patients with multidisciplinary discussion (MDD)-established CTD-ILD and compared them to a prior series of 121 biopsies from patients with MDD-established IPF or FHP.
Sci Rep
August 2024
Division of Respiratory Medicine, Department of Medicine, Sarawak General Hospital, Jalan Hospital, Ministry of Health Malaysia, Kuching, Sarawak, Malaysia.
EBUS-guided transbronchial mediastinal cryobiopsy (TBMC) has emerged as a promising biopsy tool for diagnosing hilar and mediastinal pathologies. However, several fundamental technical aspects of TBMC remain unexplored. This study aims to determine the optimal number of cryo-passes and freezing time of the ultrathin cryoprobe in EBUS-TBMC concerning specimen size and procedural diagnostic yield.
View Article and Find Full Text PDFEur J Heart Fail
November 2024
Department of Clinical-Surgical, Diagnostic and Paediatric Sciences University of Pavia, Pavia, Italy.
Aims: To describe the use and the relation to outcome of different ventilation strategies in a contemporary, large, prospective registry of cardiogenic shock patients.
Methods And Results: Among 657 patients enrolled from March 2020 to November 2023, 198 (30.1%) received oxygen therapy (OT), 96 (14.
Cytotherapy
December 2024
Immuno-Gene Therapy Factory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.
Background Aims: Dendritic cells (DCs) are professional antigen-presenting cells of the mammalian immune system. Ex vivo differentiated DCs represent a unique Advanced Therapy Medicinal Product (ATMP), used in several clinical trials as personalized cancer immunotherapy. The therapy's reliability depends on its capacity to produce high-quality mature DCs (mDCs) in compliance with Good Manufacturing Practices.
View Article and Find Full Text PDFEur Heart J Imaging Methods Pract
January 2024
Department of Medical Specialities-Pulmonology, GB Morgagni Hospital/Bologna University-Forlì-Ravenna Campus, Via Carlo Forlanini 34, 47121 Forlì, Italy.
Respirol Case Rep
July 2024
Department of Medical Specialities, Pulmonology Unit GB Morgagni-L. Pierantoni Hospital Forlì Italy.
Transbronchial lung cryobiopsy (TBLC) is a relatively new technique for obtaining lung biopsies, known for being the least invasive method while offering a high diagnostic yield, a favourable safety profile, and a significant reduction in morbidity, mortality, and hospital stay length compared to surgical lung biopsy. Radial-EBUS (r-EBUS) represent a cornerstone modality for accessing 'invisible' peripheral pulmonary lesions. However, a major drawback of these techniques is the lack of 'real-time' visualization of the biopsy being obtained.
View Article and Find Full Text PDFCancers (Basel)
July 2024
Hospital del Mar Research Institute (IMIM), Section of Gastrointestinal Surgery, Hospital del Mar, Department of Surgery, Universitat Autònoma de Barcelona, 08003 Barcelona, Spain.
Background: Radical gastrectomy remains the main treatment for gastric cancer, despite its high mortality. A clinical predictive model of 90-day mortality (90DM) risk after gastric cancer surgery based on the Spanish EURECCA registry database was developed using a matching learning algorithm. We performed an external validation of this model based on data from an international multicenter cohort of patients.
View Article and Find Full Text PDFBMJ Open
July 2024
Department of Pulmonary Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Introduction: Despite many technological advances, the diagnostic yield of bronchoscopic peripheral lung nodule analysis remains limited due to frequent mispositioning. Needle-based confocal laser endomicroscopy (nCLE) enables real-time microscopic feedback on needle positioning, potentially improving the sampling location and diagnostic yield. Previous studies have defined and validated nCLE criteria for malignancy, airway and lung parenchyma.
View Article and Find Full Text PDFBiomedicines
June 2024
Respiratory Diseases Unit, University Hospital of Modena, 41124 Modena, Italy.
Background: The molecular pathways involved in the onset and progression of idiopathic pulmonary fibrosis (IPF) still need to be fully clarified as some are shared with lung cancer development. HOXB7, a member of the homeobox () gene family, has been found involved in various cancers.
Methods: Immunohistochemical (IHC) analysis was run on lung tissue samples from surgical lung biopsy (SLB) of 19 patients with IPF, retrospectively selected from the IPF database of the University Hospital of Modena.
Minerva Surg
October 2024
Department of Surgery-Anesthesia and Intensive Care Section, Guglielmo da Saliceto Hospital, Piacenza, Italy.
EBUS-TBNA has represented a revolution in the diagnosis of intrathoracic pathologies, particularly in lung cancer staging, replacing more invasive methods such as mediastinoscopy. However, its role in diagnosing rare benign or malignant mediastinal disorders is still a matter of debate. Over the past few years, the role of EBUS-guided cryobiopsy has been increasingly emerging as an innovative and minimally invasive technique in diagnosing these disorders, with an excellent safety profile.
View Article and Find Full Text PDFAm J Respir Crit Care Med
June 2024
Department of Medical Specialities, Pulmonology Unit.
Arch Orthop Trauma Surg
November 2024
Istituto Fiorentino di Cura e Assistenza (IFCA), via del Pergolino 4/6, Florence, 50139, Italy.
Introduction: Upper-tight tourniquet is widely used in Total Knee Arthroplasty in different modalities. However, it has been associated with a negative impact on post-operative muscle strength end pain. This study aimed to investigate the effect of tourniquet on post-operative pain and recovery in enhanced recovery joint surgery.
View Article and Find Full Text PDFRespir Res
March 2024
Department of Clinical and Experimental Medicine, University of Florence and Interventional Pulmonology Unit, Careggi University Hospital, Largo Brambilla 3, Florence, 50134, Italy.
Background: The prognostic and theragnostic role of histopathological subsets in systemic sclerosis interstitial lung disease (SSc-ILD) have been largely neglected due to the paucity of treatment options and the risks associated with surgical lung biopsy. The novel drugs for the treatment of ILDs and the availability of transbronchial cryobiopsy provide a new clinical scenario making lung biopsy more feasible and a pivotal guide for treatment. The aim of our study was to investigate the usefulness of lung biopsy in SSc ILD with a systematic literature review (SLR).
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