301 results match your criteria: ""Carol Davila" University of Medicine and Pharmacy Bucharest.[Affiliation]"

Factors affecting adherence to recommendations on pre-operative cardiac testing: A cohort study.

Eur J Anaesthesiol

September 2024

From the Department of Anaesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany (AS, TS, SR, RM, GLB), Clinic for Anaesthesia, Intermediate Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Switzerland (EM), Department of Anaesthesia and Intensive Care, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania (DI), Center for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Kraków, Poland (WS), Department of Anaesthesiology and Peri-operative Medicine, Ghent University Hospital, Ghent University, Ghent, Belgium (SDH), Division of Anaesthesiology, Intensive Care, Rescue and Pain Medicine, Kantonsspital St. Gallen, St. Gallen (MF), Institute of Anaesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland (BBS), Department of translational medicine, University of Ferrara, Ferrara, Italy (SS), Department of Anaesthesia, Hospital Clinic of Barcelona, Universidad de Barcelona, Spain (PM), Department of Anaesthesiology and ICU, Ankara University Medical School, Ankara, Turkey (SCT), Department of Anaesthesiology, University Medical Centre Utrecht, Utrecht, The Netherlands (JvW), Department of Anaesthesiology, Hospital Beatriz Ângelo, Loures, Portugal (FL), Aretaieion University Hospital National and Kapodistrian University of Athens, Athens, Greece (KT), Department of Peri-operative Medicine and Intensive Care, Karolinska Hospital and Institution for Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (AG), Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany (H-JG), Anaesthesia and Intensive Care Department, University Hospital, Varese, Italy (LG), Department of Anaesthesiology, Intensive Care and Pain Management, Pomeranian Medical University, Szczecin, Poland (KK), Department of Anaesthesiology, Heidelberg University Hospital, Heidelberg, Germany (JL), Anaesthesia and Intensive Care Department III, Carol Davila University of Medicine and Pharmacy Bucharest, Central Military Emergency University Hospital 'Dr Carol Davila', Bucharest, Romania (DC), Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom (SJH), and CARID, Cardiovascular Research Institute Düsseldorf, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Germany (GLB, AS, SR, RM).

Background: Cardiac risk evaluation prior to noncardiac surgery is fundamental to tailor peri-operative management to patient's estimated risk. Data on the degree of adherence to guidelines in patients at cardiovascular risk in Europe and factors influencing adherence are underexplored.

Objectives: The aim of this analysis was to describe the degree of adherence to [2014 European Society of Cardiology (ESC)/European Society of Anaesthesiology (ESA) guidelines] recommendations on rest echocardiography [transthoracic echocardiography (TTE)] and to stress imaging prior to noncardiac surgery in a large European sample and to assess factors potentially affecting adherence.

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: Secretory carcinoma of the breast is an uncommon histological subtype of breast cancer. There is little research on this entity and only a few larger studies, which lack consensus. We aim to report a particular apocrine differentiation in this subtype and ponder upon the clinical outcome of this case.

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Idiopathic superior mesenteric vein (SMV) stenosis, where no clear causative factor is identifiable, remains a clinical rarity. We present a detailed case report of a patient with idiopathic stenosis of the SMV who underwent successful endovascular stenting. This report outlines the patient's clinical presentation, diagnostic imaging findings, procedural approach by the interventional radiology team, and subsequent management.

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(1) Background: Hypertriglyceridemia (HTG) is a well-known metabolic condition associated with an increased risk of acute pancreatitis. In this study, we tried to establish whether there are any significant disparities concerning recurrence rate, intensive care unit (ICU) admission, hospital (ICU and total) length of stay (LoS), morphology, severity and age between HTG-induced acute pancreatitis and any other known cause of pancreatitis (OAP). (2) Methods: The research was a retrospective unicentric cohort study, using information from the Bucharest Acute Pancreatitis Index (BUC-API) registry, a database of 1855 consecutive cases of acute pancreatitis.

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Pulmonary hypertension (PH) is a progressive and invalidating condition despite available therapy. Addressing complications such as left main coronary artery compression (LMCo) due to the dilated pulmonary artery (PA) may improve symptoms and survival. Nevertheless, clear recommendations are lacking.

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Hypertension is often linked with metabolic risk factors that share common pathophysiological pathways. Despite wide-spread availability of multiple drug classes, optimal blood pressure (BP) control remains challenging. Increased central sympathetic outflow is frequently neglected as a critical regulator of both circulatory and metabolic pathways and often remains unopposed therapeutically.

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Background: Hereditary adenomatous polyposis syndromes, including familial adenomatous polyposis and other rare adenomatous polyposis syndromes, increase the lifetime risk of colorectal and other cancers.

Methods: A team of 38 experts convened to update the 2008 European recommendations for the clinical management of patients with adenomatous polyposis syndromes. Additionally, other rare monogenic adenomatous polyposis syndromes were reviewed and added.

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Article Synopsis
  • Skin cancers are super common, especially in people with fair skin, and most of them are caused by UV rays from the sun, which means we can do things to prevent them.
  • Experts from different continents suggest that fair-skinned people, especially kids, should stay out of the sun when the UV level is 3 or higher and use protection like hats, sunglasses, clothing, and sunscreen.
  • They also believe sunbathing and using tanning beds are unhealthy, so they want to spread these ideas to help everyone stay safe from skin cancer.
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Background: Breast cancer is the most frequently diagnosed cancer among women, responsible for the highest number of cancer-related deaths worldwide. There is limited data available related to serum tumor markers in breast cancer and other blood parameters or other glandular laboratory parameters. This study aims to evaluate the correlation of tumor-specific markers for breast cancer with other blood parameters and how these correlations could impact clinical management.

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The study proposes a dynamic spatio-temporal profile of the distribution of tuberculosis incidence and air pollution in Romania, where this infectious disease induces more than 8,000 new cases annually. The descriptive analysis for the years 2012-2021 assumes an identification of the structuring patterns of mycobacterium tuberculosis risk in the Romanian population, according to gender and age, exploiting spatial modeling techniques of time series data. Through spatial autocorrelation, the degree of similarity between the analyzed territorial systems was highlighted and the relationships that are built between the analysis units in spatial proximity were investigated.

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Article Synopsis
  • This study compares two surgical methods, Hartmann's procedure (HP) and resection with primary anastomosis (RPA), for treating acute left-sided colonic emergencies among 1215 patients from 204 centers globally.
  • Results showed that while HP was the more common treatment (57.3%), RPA was favored for younger patients with fewer health issues and those needing surgery sooner.
  • The study concluded that although HP is still widely used, RPA might be the better option, emphasizing the importance of patient characteristics and surgeon experience in determining treatment choice.
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Introduction: Spontaneous tumor regression is an extremely rare phenomenon in the oncology field.

Presentation Of Case: We present the case of a 72-years-old male patient presenting with a bulky hepatic tumor mass located in segment V and extending into segments IVb and VI with MRI features of atypical cholangiocarcinoma with a liver metastasis in segment III. In first surgical step, excision of the metastasis, and ligation of the right portal vein was done.

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  • The field of plastic surgery is rapidly changing due to new technologies and treatment methods, which require updated protocols and problem-solving strategies.
  • Surgical decisions in reconstructive surgery are influenced by factors like the cause of the defect, the patient's needs and background, and the surgeon’s skill level.
  • Reconstructive surgery frameworks aim to minimize risks and improve outcomes, offering structured approaches for researchers to tackle unique clinical challenges using a combination of theory and practical techniques.
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  • Burn injuries lead to serious trauma with high morbidity and mortality, making prompt management essential for improving patient outcomes, particularly focusing on biological parameters like thrombocytopenia.
  • A two-year study of 90 severely burned patients revealed that thrombocytopenia was linked to a worse prognosis, as those with low platelet counts had higher mortality rates, especially in conjunction with other severe burn characteristics.
  • The findings suggest thrombocytopenia can serve as an early warning sign for complications and may help predict outcomes in patients with severe burns, especially in those experiencing sepsis.
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This research investigates the trueness and precision of 3D printing technology in dental applications, specifically focusing on dimensional variations observed in models printed at different angles. The methodology involved importing a dental model into slicing software, adjusting its orientation, and implementing support structures for stability. Subsequently, the model underwent 3D printing five times for each orientation using appropriate equipment and underwent post-processing steps, including cleaning, washing, and UV-light post-curing.

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Article Synopsis
  • * A review of 29 studies identified two main strategies for increasing HIV testing: test-all and indicator-condition-based approaches, which showed varying effectiveness.
  • * While testing interventions improved detection rates, significant knowledge gaps and variations in effectiveness across regions suggest a need for better adherence to guidelines and more comprehensive studies.
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Burn patients manifest all components of Virchow's triad, amplifying the concern for venous thromboembolism (VTE). Routine prophylaxis for VTE remains a subject of debate, with the central concern being the occurrence of associated adverse events. We conducted a five-year retrospective study on burn patients admitted to our burn center.

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Pancreatic ductal adenocarcinoma (PDAC) stands out as the predominant malignant neoplasm affecting the pancreas, characterized by a poor prognosis, in most cases patients being diagnosed in a nonresectable stage. Image-based artificial intelligence (AI) models implemented in tumor detection, segmentation, and classification could improve diagnosis with better treatment options and increased survival. This review included papers published in the last five years and describes the current trends in AI algorithms used in PDAC.

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  • Hydatid cyst disease is primarily a parasitic infection affecting organs like the liver and lungs, with surgical treatment options including both open surgery and laparoscopy, often depending on the location of the cysts.
  • The majority of cases, especially with mesenteric locations, tend to favor open surgery, which is preferred in over 85% of the instances due to complications associated with cyst coexistence.
  • A rare case demonstrated successful laparoscopic treatment of multiple hydatid cysts, leading to a smooth recovery, highlighting the potential benefits of minimally invasive approaches in select situations.
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Three-dimensional (3D) bioprinting is the use of computer-controlled transfer processes for assembling bioinks (cell clusters or materials loaded with cells) into structures of prescribed 3D organization. The correct bioprinting parameters ensure a fast and accurate bioink deposition without exposing the cells to harsh conditions. This study seeks to optimize pneumatic extrusion-based bioprinting based on hydrogel flow rate and extrusion speed measurements.

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Laparoscopic cholecystectomy (LC) is the gold standard treatment in acute cholecystitis. However, one in six cases is expected to be difficult due to intense inflammation and suspected adherence to and involvement of adjacent important structures, which may predispose patients to higher risk of vascular and biliary injuries. In this study, we aimed to identify the preoperative parameters with predictive value for surgical difficulties.

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Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study.

Br J Anaesth

April 2024

Department of Anaesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany; CARID, Cardiovascular Research Institute Düsseldorf, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.

Article Synopsis
  • The 2022 European Society of Cardiology guidelines for preoperative evaluations aimed to improve the detection of pathological findings compared to the 2014 guidelines.
  • A study analyzed data from 15,529 patients and found that the updated recommendations changed testing protocols for many, but did not enhance the overall effectiveness of cardiac testing.
  • The use of B-type natriuretic peptide (NT-proBNP) for risk estimation did not improve pathological findings, and adherence to the new guidelines showed no significant link to major adverse cardiovascular events.
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