VITAMIN D DEFICIENCY, BONE TURNOVER MARKERS AND ARTERIAL CALCIFICATIONS IN NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS.

Introduction: Vitamin D [25(OH)D] deficiency is prevalent in chronic kidney disease (CKD), related to bone turnover and potentially involved in arterial calcifications.

Objective: To evaluate vitamin D status in non-dialysis CKD patients and its relationships with bone turnover markers (BTM) and arterial calcifications.

Design: Cross-sectional, prospective, multicentric study.

NUTRITIONAL OR ACTIVE VITAMIN D FOR THE CORRECTION OF MINERAL METABOLISM ABNORMALITIES IN NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS?

Context: Benefits of vitamin D therapies in chronic kidney disease (CKD) are debated.

Objective: To compare the effects of medium-term native (VitD) and active (VDRA) vitamin D on parameters of mineral metabolism and arterial function in non-dialysis CKD.

Design: Open-label, active comparator, randomized study.