102 results match your criteria: ""Carol Davila" Central Military Emergency Hospital[Affiliation]"
J Funct Biomater
December 2024
Department of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
With the development of 3D bioprinting and the creation of innovative biocompatible materials, several new approaches have brought advantages to patients and surgical teams. Increasingly more bone defects are now treated using 3D-bioprinted prostheses and implementing new solutions relies on the ability of engineers and medical teams to identify methods of anchoring 3D-printed prostheses and to reveal the potential influence of bioactive materials on surrounding tissues. In this paper, we described why limb salvage surgery based on 3D bioprinting is a reliable and effective alternative to amputations, and why this approach is considered the new standard in modern medicine.
View Article and Find Full Text PDFEFORT Open Rev
October 2024
Center of Orthopedics and Traumatology, University Hospital Brandenburg/Havel, Brandenburg Medical School Theodor Fontane, Brandenburg a.d.H., Germany.
Purpose: The purpose of the present scoping review is to identify sources of heterogeneity in reporting domains that have the potential to improve surgical decision-making in reverse shoulder arthroplasty associated with glenoid bone grafting.
Methods: A scoping review was conducted according to the JBI and PRISMA ScR guidelines. Articles covering glenoid bone grafting at the time of reverse shoulder replacement, published between 2012 and 2022 in MEDLINE, Scopus, Epistemonikos, Web of Science, and Cochrane Database of Systematic Reviews, were searched.
J Pers Med
August 2024
"Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Thrombotic events during pregnancy are burdened by an increased risk of morbidity and mortality, despite innovations in their diagnosis and treatment. Given their multifactorial etiology, it is important to understand all the pathophysiological mechanisms but especially to achieve correct and timely diagnosis. Pulmonary embolism (PE) during pregnancy represents a rare event, with an incidence of 1 per 1000 pregnancies, but it is also one of the leading causes of death during pregnancy.
View Article and Find Full Text PDFJ Clin Med
September 2024
Department of Orthopaedics, Traumatology and Hand Surgery, Faculty of Medicine, Wroclaw Medical University, 50556 Wroclaw, Poland.
Despite the growing popularity of training with a controlled form of vascular occlusion, known as blood flow restriction (BFR) training, in the rehabilitation of orthopedic patients and sports medicine, there remains ample space for understanding the basis of its mechanism. The pilot study assessed the effect of BFR during a low-load resistance training unit on knee flexor muscle fatigue, intending to decide whether a larger trial is needed and feasible. : The study used a prospective, randomized, parallel, double-blind, placebo-controlled design.
View Article and Find Full Text PDFMedicina (Kaunas)
September 2024
Dr. Carol Davila University Central Military Emergency Hospital, "Carol Davila" University of Medicine and Pharmacy, Calea Plevnei 134, 010825 Bucharest, Romania.
Curr Issues Mol Biol
September 2024
Department of Radiology and Medical Imaging, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Int J Mol Sci
September 2024
Pathophysiology Department, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Curr Issues Mol Biol
July 2024
Department of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Capsaicin, the most prominent pungent compound of chilli peppers, has been used in traditional medicine systems for centuries; it already has a number of established clinical and industrial applications. Capsaicin is known to act through the TRPV1 receptor, which exists in various tissues; capsaicin is hepatically metabolised, having a half-life correlated with the method of application. Research on various applications of capsaicin in different formulations is still ongoing.
View Article and Find Full Text PDFLife (Basel)
July 2024
Department of Infectious Diseases, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Obesity is an important condition affecting the quality of life of numerous patients and increasing their associated risk for multiple diseases, including tumors and immune-mediated disorders. Inflammation appears to play a major role in the development of obesity and represents a central point for the activity of cellular and humoral components in the adipose tissue. Macrophages play a key role as the main cellular component of the adipose tissue regulating the chronic inflammation and modulating the secretion and differentiation of various pro- and anti-inflammatory cytokines.
View Article and Find Full Text PDFInt J Mol Sci
June 2024
Department of Oral and Maxillofacial Surgery, Ramon y Cajal University Hospital, 28034 Madrid, Spain.
Oral squamous cell carcinoma (OSCC), the most common type of head and neck cancer, remains a highly challenging cancer to treat, largely due to the late diagnosis in advanced stages of the disease, which occurs in more than half of cases [...
View Article and Find Full Text PDFJ Clin Med
May 2024
Department of Cardio-Thoracic Pathology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050471 Bucharest, Romania.
Chronic inflammation is a constant phenomenon which accompanies the heart failure pathophysiology. In all phenotypes of heart failure, irrespective of the ejection fraction, there is a permanent low-grade activation and synthesis of proinflammatory cytokines. Many classes of anti-remodelling medication used in the treatment of chronic heart failure have been postulated to have an anti-inflammatory effect.
View Article and Find Full Text PDFSurg Radiol Anat
July 2024
Division of Anatomy, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, Bucharest, 020021, Romania.
Purpose: This study aims to assess the anatomical possibilities of the jugular bulb (JB).
Methods: Fifty archived CBCT scans were analyzed.
Results: The average distance between the internal acoustic canal (IAC) and the JB was 7.
Medicina (Kaunas)
April 2024
Division of Anatomy, Department 1, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, RO-020021 Bucharest, Romania.
: The upper posterior teeth are typically regarded as being exclusively inferior to the maxillary sinus (MS). The expansion of the nasal fossa above the maxillary alveolar base (MAB) needs better investigation. The hypothesis was raised that the MAB in the upper premolar region, which is usually addressed by surgeons for the elevation of the antral floor, is not exclusively beneath the MS.
View Article and Find Full Text PDFLife (Basel)
April 2024
Department of Internal Medicine 2, Dr. Carol Davila University Central Military Emergency Hospital, 010825 Bucharest, Romania.
Brain Sci
April 2024
Department of Neurosurgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
In the original publication [...
View Article and Find Full Text PDFJ Pers Med
March 2024
Department 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Introduction: Oropharyngeal cancer requires a comprehensive evaluation of treatment options, including surgery, radiation therapy, and chemotherapy. It is crucial to customize these treatments based on the stage of the tumor and the overall health of the patient, enabling personalized or combined approaches. Transoral surgical techniques have regained popularity due to the advancements and limitations of non-surgical strategies.
View Article and Find Full Text PDFBiomimetics (Basel)
March 2024
Department of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
The incidence of microbial infections in orthopedic prosthetic surgeries is a perennial problem that increases morbidity and mortality, representing one of the major complications of such medical interventions. The emergence of novel technologies, especially 3D printing, represents a promising avenue of development for reducing the risk of such eventualities. There are already a host of biomaterials, suitable for 3D printing, that are being tested for antimicrobial properties when they are coated with bioactive compounds, such as antibiotics, or combined with hydrogels with antimicrobial and antioxidant properties, such as chitosan and metal nanoparticles, among others.
View Article and Find Full Text PDFInt Orthop
May 2024
Romanian Shoulder Institute, ORTOPEDICUM - Orthopaedic Surgery & Sports Clinic, Bucharest, Romania.
The management of the long head of the biceps tendon (LHBT) during shoulder arthroscopy has been a subject of controversy for many years, with evolving discussions and trends. Despite long-standing debate, the nature of the surgical indication regarding how to treat concomitent LHBT injuries has undergone changes in recent years. It now extends beyond the timing of tenotomy to encompass considerations of alternative methods for preserving the LHBT, along with an ongoing exploration of how it can be effectively utilized in reconstructive shoulder surgery.
View Article and Find Full Text PDFInt J Mol Sci
January 2024
Department of Physiology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Cannabinoids have incited scientific interest in different conditions, including malignancy, due to increased exposure to cannabis. Furthermore, cannabinoids are increasingly used to alleviate cancer-related symptoms. This review paper aims to clarify the recent findings on the relationship between cannabinoids and oral cancer, focusing on the molecular mechanisms that could link cannabinoids with oral cancer pathogenesis.
View Article and Find Full Text PDFJ Funct Biomater
December 2023
Department of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Boulevard, 050474 Bucharest, Romania.
Along with the rapid and extensive advancements in the 3D printing field, a diverse range of uses for 3D printing have appeared in the spectrum of medical applications. Vat photopolymerization (VPP) stands out as one of the most extensively researched methods of 3D printing, with its main advantages being a high printing speed and the ability to produce high-resolution structures. A major challenge in using VPP 3D-printed materials in medicine is the general incompatibility of standard VPP resin mixtures with the requirements of biocompatibility and biofunctionality.
View Article and Find Full Text PDFJ Clin Med
January 2024
Department of Gastroenterology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Monitoring disease activity in inflammatory bowel disease (IBD) is challenging since clinical manifestations do not represent reliable surrogates for an accurate reflection of the inflammatory burden. Endoscopic remission had been the most significant endpoint target in the last years; nevertheless, a remarkable proportion of patients continue to relapse despite a normal-appearing mucosa, highlighting that endoscopy may underestimate the true extent of the disease. A subtle hint of the importance that histology plays in the long-term course of the disease has been endorsed by the STRIDE-II consensus, which recommends considering histologic healing for ulcerative colitis (UC), even though it is not stated to be a compulsory formal target.
View Article and Find Full Text PDFJ Clin Med
December 2023
Department of Internal Medicine and Cardiology, "Prof. Dr. Th. Burghele" Clinical Hospital, 061344 Bucharest, Romania.
Chronic heart failure is a terminal point of a vast majority of cardiac or extracardiac causes affecting around 1-2% of the global population and more than 10% of the people above the age of 65. Inflammation is persistently associated with chronic diseases, contributing in many cases to the progression of disease. Even in a low inflammatory state, past studies raised the question of whether inflammation is a constant condition, or if it is, rather, triggered in different amounts, according to the phenotype of heart failure.
View Article and Find Full Text PDFFront Med (Lausanne)
October 2023
Center for Translational Medicine, Semmelweis University, Budapest, Hungary.
Background: Routine anticoagulation therapy in acute pancreatitis (AP) is not recommended by the guidelines in the field, although it is frequently used in clinical practice.
Objectives: We aimed to analyze the efficacy and safety of adding anticoagulants therapy to AP management.
Methods: The systematic search was performed in three databases on the 14th of October 2022 without restrictions.
Clin Exp Rheumatol
December 2023
Department of Autoimmune Diseases, ICMiD, Hospital Clínic, Barcelona, and Department of Medicine, University of Barcelona, Spain.
Clin Exp Rheumatol
December 2023
Department of Autoimmune Diseases, ICMiD, Hospital Clínic, Barcelona, and Department of Medicine, University of Barcelona, Spain.
Objectives: To analyse how the potential exposure to air pollutants can influence the key components at the time of diagnosis of Sjögren's phenotype (epidemiological profile, sicca symptoms, and systemic disease).
Methods: For the present study, the following variables were selected for harmonization and refinement: age, sex, country, fulfilment of 2002/2016 criteria items, dry eyes, dry mouth, and overall ESSDAI score. Air pollution indexes per country were defined according to the OECD (1990-2021), including emission data of nitrogen and sulphur oxides (NO/SO), particulate matter (PM2.