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Neurodevelopmental Follow-Up in Children with Intrauterine and Perinatal Exposure to Chikungunya Virus.
J Pediatr
January 2025
Department of Acute Febrile Illnesses, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Objective: To investigate the effects of intrauterine and perinatal exposure to chikungunya virus (CHIKV) on neurodevelopment in infants and toddlers.
Study Design: We conducted a cohort study comparing children with intrauterine or perinatal exposure to maternal CHIKV infection with unexposed controls in Rio de Janeiro, Brazil. Neurodevelopment was assessed with General Movement Assessments (GMA) in the first six months of life, and the Bayley-III Scales of Infant and Toddler Development and Modified Checklist for Autism in Toddlers (M-CHAT) for older children.
Isolation, characterization, and genome sequencing analysis of a novel phage HBW-1 of Salmonella.
Microb Pathog
January 2025
Laboratory of Molecular Microbiology and Food Safety, Zhejiang University College of Animal Sciences, Hangzhou 310058, China; Hainan Institute of Zhejiang University, Sanya 572025, China; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China. Electronic address:
Salmonella presents a significant threat to the health of animals and humans, especially with the rise of strains resistant to multiple drugs. This highlights the necessity for creating sustainable and efficient practical approaches to managing salmonellosis. The most recent and safest approach to combat antimicrobial resistance-associated infections is lytic bacteriophages.
View Article and Find Full Text PDFAstragaloside IV ameliorates autism-like behaviors in BTBR mice by modulating Camk2n2-dependent OXPHOS and neurotransmission in the mPFC.
J Adv Res
January 2025
Department of Military Cognitive Psychology, School of Psychology, Third Military Medical University (Army Medical University), Chongqing, China. Electronic address:
Introduction: Autism spectrum disorder (ASD) represents a multifaceted set of neurodevelopmental conditions marked by social deficits and repetitive behaviors. Astragaloside IV (ASIV), a natural compound derived from the traditional Chinese herb Astragali Radix, exhibits robust neuroprotective effects. However, whether ASIV can ameliorate behavioral deficits in ASD remains unknown.
View Article and Find Full Text PDFResonance SERS probe based on the bifunctional molecule IR808 combined with SA test strips for highly sensitive detection of monkeypox virus.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Clinical Research Institute, Department of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, College of Chemistry and Chemical Engineering, College of Energy, College of Physical Science and Technology, and Discipline of Intelligent Instrument and Equipment, Xiamen University, Xiamen 361005 China; Scientific Research Foundation of State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, Xiamen 361005 China. Electronic address:
As a zoonotic virus, highly sensitive detection of monkeypox virus is crucial for its prevention and control due to its rapid increase in cases worldwide and the extremely high risk of virus transmission. In this paper, based on the principle of antigen-antibody specific recognition, an ultrasensitive resonance Raman biosensing probe was prepared using a molecule with the bifunctionality of resonance Raman effect and capturing antibody; and with the strong affinity of the biotin-streptavidin (Bio-SA) system, Bio-antibody and SA test strips were prepared. To match the T-line of the test strip, a portable Raman instrument with a strip-shaped spot was designed.
View Article and Find Full Text PDFA comparison of energy dispersive spectroscopy in transmission scanning electron microscopy with scanning transmission electron microscopy.
Ultramicroscopy
January 2025
Mechanical Engineering, University of Michigan, USA.
The objective of this work was to explore the capabilities of a field emission gun scanning electron microscope (FEG-SEM) equipped with a transmission scanning electron detector (TSEM) and energy dispersive spectroscopy (EDS) to identify nanoscale chemical heterogeneities in a gas atomization reaction synthesis (GARS) steel sample. The results of this analysis were compared to the same study conducted with scanning transmission electron microscopy (STEM) with EDS mapping. TSEM-EDS was performed using the standard spectral analysis approach, i.
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