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Niosome Preparation Techniques and Structure-An Illustrated Review.
Pharmaceutics
January 2025
Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
A comprehensive review of recent research on niosomes was conducted using a mixed methodology, including searches in databases such as Scopus, PubMed, and Web of Science (WoS). Articles were selected based on relevance. The current review examines the historical development of niosomes focusing on the methods of preparations and the contemporary strategies and prospective advancements within the realm of drug delivery systems, highlighting innovative approaches across transdermal, oral, and cellular delivery.
View Article and Find Full Text PDFTrench MOS Schottky Diodes: A Physics-Based Analytical Model Approach to Charge Sharing.
Micromachines (Basel)
January 2025
Power Solutions Group, Onsemi, Scottsdale, AZ 85250, USA.
Trench MOS Barrier Schottky (TMBS) rectifiers offer superior static and dynamic electrical characteristics when compared with planar Schottky rectifiers for a given active die size. The unique structure of TMBS devices allows for efficient manipulation of the electric field, enabling higher doping concentrations in the drift region and thus achieving a lower forward voltage drop (VF) and reduced leakage current (IR) while maintaining high breakdown voltage (BV). While the use of trenches to push electric fields away from the mesa surface is a widely employed concept for vertical power devices, a significant gap exists in the analytical modeling of this effect, with most prior studies relying heavily on computationally intensive numerical simulations.
View Article and Find Full Text PDFSize-controlled assembly of phase separated protein condensates with interfacial protein cages.
Nat Commun
January 2025
Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Phase separation of specific proteins into liquid-like condensates is a key mechanism for forming membrane-less organelles, which organize diverse cellular processes in space and time. These protein condensates hold immense potential as biomaterials capable of containing specific sets of biomolecules with high densities and dynamic liquid properties. Despite their appeal, methods to manipulate protein condensate materials remain largely unexplored.
View Article and Find Full Text PDFUiO-66 Metal-Organic Framework Membranes: Structural Engineering for Separation Applications.
Membranes (Basel)
January 2025
Faculty of Arts and Sciences, Beijing Normal University, Zhuhai 519087, China.
Metal-organic frameworks (MOFs) have been recognized as promising materials for membrane-based separation technologies due to their exceptional porosity, structural tunability, and chemical stability. This review presents a comprehensive discussion of the advancements in structure engineering and design strategies that have been employed to optimize UiO-66 membranes for enhanced separation performance. Various synthesis methods for UiO-66 membranes are explored, with a focus on modulated approaches that incorporate different modulators to fine-tune nucleation rates and crystallization processes.
View Article and Find Full Text PDFSynergistic Approach of High-Precision 3D Printing and Low Cell Adhesion for Enhanced Self-Assembled Spheroid Formation.
Biosensors (Basel)
December 2024
School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China.
Spheroids, as three-dimensional (3D) cell aggregates, can be prepared using various methods, including hanging drops, microwells, microfluidics, magnetic manipulation, and bioreactors. However, current spheroid manufacturing techniques face challenges such as complex workflows, the need for specialized personnel, and poor batch reproducibility. In this study, we designed a support-free, 3D-printed microwell chip and developed a compatible low-cell-adhesion process.
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