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Intraoperative evaluation using a multimodality probe of temperature-dependent neurovascular modulation during focal brain cooling.
Clin Neurophysiol
March 2025
Department of Neurosurgery, Yamaguchi University School of Medicine, Ube, Japan.
Objective: This study aimed to assess the effects of focal brain cooling (FBC) on human brain tissue through use of multiple sensing techniques by monitoring cerebrovascular activity and brain temperature.
Methods: Intraoperative brain activity monitoring using a multimodality probe capable of measuring brain temperature, electrocorticography (ECoG) and changes in cerebral hemoglobin concentration was performed in 13 patients with refractory epilepsy. Brain temperature and neurovascular activity were measured beneath and surrounding the FBC device.
Machine-learning heat flux closure for multi-moment fluid modeling of nonlinear Landau damping.
Proc Natl Acad Sci U S A
March 2025
Department of Astronomy, Center for Space Physics, Boston University, Boston, MA 02215.
Nonlinear plasma physics problems are usually simulated through comprehensive modeling of phase space. The extreme computational cost of such simulations has motivated the development of multi-moment fluid models. However, a major challenge has been finding a suitable fluid closure for these fluid models.
View Article and Find Full Text PDFExploiting Polynomial Chaos Expansion for Rapid Assessment of the Impact of Tissue Property Uncertainties in Low-Intensity Focused Ultrasound Stimulation.
Bioelectromagnetics
April 2025
Care & Cure Lab of the Electromagnetics Group (EM4Care+Cure), Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
Neuromodulation with low-intensity focused ultrasound (LIFUS) holds significant promise for noninvasive treatment of neurological disorders, but its success relies heavily on accurately targeting specific brain regions. Computational model predictions can be used to optimize LIFUS, but uncertain acoustic tissue properties can affect prediction accuracy. The Monte Carlo method is often used to quantify the impact of uncertainties, but many iterations are generally needed for accurate estimates.
View Article and Find Full Text PDFPredictive control of musculotendon loads across fast and slow-twitch muscles in a simulated system with parallel actuation.
Wearable Technol
February 2025
Neuromuscular Robotics Laboratory, Department of Biomechanical Engineering, University of Twente, Enschede, the Netherlands.
Research in lower limb wearable robotic control has largely focused on reducing the metabolic cost of walking or compensating for a portion of the biological joint torque, for example, by applying support proportional to estimated biological joint torques. However, due to different musculotendon unit (MTU) contractile speed properties, less attention has been given to the development of wearable robotic controllers that can steer MTU dynamics directly. Therefore, closed-loop control of MTU dynamics needs to be robust across fiber phenotypes, that is ranging from slow type I to fast type IIx in humans.
View Article and Find Full Text PDFHeterojunctions Based on 2D Materials for Pulse Laser Applications.
ACS Nano
March 2025
Department of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China.
In recent years, heterostructures composed of two-dimensional (2D) materials have demonstrated broad application prospects across various domains, primarily attributed to their exceptional electrical and optical properties. The superior performance of these heterostructures is rooted in the interlayer interactions and the diversity of the constituent materials. Notably, their applications have been greatly advanced in optical fields such as photodetectors, lasers, modulators, optical sensors, and nonlinear optics.
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