At the time of his death in 1776, most medical doctors in Paris challenged the views of Théophile de Bordeu on the "hormonal" action of internal secretions. At the University of Leuven, however, his concepts on the hormonal activity of semen had been positively approached in 1780 on the occasion of a public debate (disputatio), conducted by the medical student, Gregorius-Josephus Jacquelart. Therefore, we consider G.J. Jacquelart as being the first andrologist at the University of Leuven.
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http://dx.doi.org/10.1016/s0301-2115(98)00193-6 | DOI Listing |
Environ Sci Technol
January 2025
Laboratory of Evolutionary Stress Ecology and Ecotoxicology, University of Leuven, Charles Deberiotstraat 32, 3000 Leuven, Belgium.
Despite pleas to consider both evolutionary and multistressor climate change perspectives to improve ecological risk assessment, the much needed combination of both perspectives is largely missing. This is especially important when evaluating the costs of the evolution of genetic tolerance to pollutants as these costs may become visible only under combined exposure to the pollutant and warming due to energetic constraints. We investigated the costs of chlorpyrifos tolerance in when sequentially exposed to 4-day pesticide treatments and 4-day heat spike treatments.
View Article and Find Full Text PDFUltrasound Obstet Gynecol
January 2025
Hospital Necker-Enfants Malades, AP-HP, Uni- versité Paris Descartes, Paris, France.
Leukemia
January 2025
Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.
Expression of CD2, CD25 and/or CD30 in extracutaneous mast cells (MC) is a minor diagnostic criterion for systemic mastocytosis (SM) in the classification of the World Health Organization and International Consensus Classification. So far, it remains unknown whether expression of these antigens on MC is of prognostic significance in SM. We performed a retrospective multi-center study of patients with SM using the data set of the registry of the European Competence Network on Mastocytosis, including 5034 patients with various MC disorders.
View Article and Find Full Text PDFNat Hum Behav
January 2025
Faculty of Psychology and Educational Sciences; Equal Opportunities & Diversity Office, University of Geneva, Genève, Switzerland.
Nat Rev Nephrol
January 2025
APHP, Reference Center for Rare Diseases of Calcium and Phosphate Metabolism, and Filière OSCAR, endo ERN and ERN BOND, Paris, France.
X-linked hypophosphataemia (XLH) is a rare metabolic bone disorder caused by pathogenic variants in the PHEX gene, which is predominantly expressed in osteoblasts, osteocytes and odontoblasts. XLH is characterized by increased synthesis of the bone-derived phosphaturic hormone fibroblast growth factor 23 (FGF23), which results in renal phosphate wasting with consecutive hypophosphataemia, rickets, osteomalacia, disproportionate short stature, oral manifestations, pseudofractures, craniosynostosis, enthesopathies and osteoarthritis. Patients with XLH should be provided with multidisciplinary care organized by a metabolic bone expert.
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