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Investigating amygdala nuclei volumes in military personnel with post-traumatic stress disorder, major depressive disorder, and adjustment disorder: A retrospective cross-sectional study using clinical routine data.
PLoS One
January 2025
Department of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Background: Post-traumatic Stress Disorder (PTSD), Major Depressive Disorder (MDD), and Adjustment Disorder (AdjD) are highly prevalent among military personnel, often presenting diagnostic challenges due to overlapping symptoms and reliance on self-reporting. The amygdala, particularly the basolateral complex involved in fear-related memory formation and extinction recall, plays a crucial role in emotional processing. Abnormalities in these amygdala nuclei are implicated in PTSD and may distinguish it from other disorders like MDD and AdjD, where these mechanisms are less central.
View Article and Find Full Text PDFObjective: Trauma survivors are more likely than others to use cannabis, and post-traumatic stress disorder (PTSD) commonly co-occurs with cannabis use disorder (CUD). Automatic memory associations between trauma reminders and cannabis use have been suggested as contributing mechanisms. These associations can be studied experimentally by manipulating trauma cue exposure in a cue-reactivity paradigm (CRP) and examining effects on the accessibility of cannabis information in memory in trauma survivors with and without PTSD.
View Article and Find Full Text PDFAutomatic screening for posttraumatic stress disorder in early adolescents following the Ya'an earthquake using text mining techniques.
Front Psychiatry
December 2024
Faculty of Psychology, Beijing Normal University, Beijing, China.
Background: Self-narratives about traumatic experiences and symptoms are informative for early identification of potential patients; however, their use in clinical screening is limited. This study aimed to develop an automated screening method that analyzes self-narratives of early adolescent earthquake survivors to screen for PTSD in a timely and effective manner.
Methods: An inquiry-based questionnaire consisting of a series of open-ended questions about trauma history and psychological symptoms, was designed to simulate the clinical structured interviews based on the DSM-5 diagnostic criteria, and was used to collect self-narratives from 430 survivors who experienced the Ya'an earthquake in Sichuan Province, China.
Using Technology to Support Measurement-Based Care: Design and Implementation of the Measurement-Assisted Care Program.
Psychiatr Serv
October 2024
Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora (Steidtmann, Green, MacPhee, Nagle-Yang, Schwenk, Cooke, Santisteban, Dempsey); Brain and Behavior Innovation Center, University of Colorado Anschutz Medical Campus, Aurora (Steidtmann, Cooke, Santisteban, Dempsey); Division of Hospital Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (Raffel); Institute for Healthcare Quality, Safety and Efficiency, University of Colorado School of Medicine, Aurora (Raffel).
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- * The program integrated various patient-reported outcome measures into the electronic check-in process, resulting in significant increases in completion rates for assessments like PHQ-9 and GAD-7, particularly during telehealth visits.
- * Clinicians found MAC to be helpful, with 90% reporting its usefulness, and 78% utilizing MAC data to inform their patient care, indicating that technology can effectively support patient-centered workflows in psychiatry.
The role of objective sleep in implicit and explicit affect regulation: A comprehensive review.
Neurobiol Stress
July 2024
San Diego VA Health Care System, San Diego, CA, USA.
Impairments in sleep and affect regulation are evident across a wide range of mental disorders. Understanding the sleep factors that relate to affect regulatory difficulties will inform mechanistic understanding and aid in treatment. Despite rising interest, some research challenges in this area include integrating across different clinical and non-clinical literatures investigating the role of sleep architecture (measured with polysomnography) and experimentally manipulated sleep, as well as integrating more explicit versus implicit affect regulation processes.
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