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Improved Hematology Analysis Based on Microfluidic Impedance Spectroscopy: Erythrocyte Orientation and Anisotropic Dielectric Properties of Flowing Blood.
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School of Mechanical and Robotics Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Republic of Korea.
Electrochemical impedance spectroscopy has great potential for laboratory blood tests. The overall aim of this study is to develop a microfluidic sensor for determining the physical properties and hematological parameters of blood based on its dielectric spectra. Impedance was measured in flowing blood to prevent aggregation and sedimentation at frequencies between 40 Hz and 110 MHz.
View Article and Find Full Text PDFEffects of Printing Orientation on the Tensile, Thermophysical, Smoke Density, and Toxicity Properties of Ultem 9085.
Polymers (Basel)
January 2025
Institute of Chemistry and Chemical Technology, Faculty of Natural Sciences and Technology, Riga Technical University, P. Valdena 3, LV-1048 Riga, Latvia.
Despite the impressive properties of additively manufactured products, their inherent anisotropy is a crucial challenge for polymeric parts made via fused filament fabrication (FFF). This study compared the tensile, thermophysical, smoke density, and toxicity characteristics of Ultem 9085 (a blend of polyetherimide and polycarbonate) for samples printed in various orientations (X, Y, and Z). The results revealed that mechanical properties, such as elastic modulus and tensile strength, significantly differed from the Z printing orientation, particularly in the X and Y printing layer orientations.
View Article and Find Full Text PDFDetermine the Relative Aromaticity of Bilayer Graphyne, Bilayer Graphdiyne, and Bilayer Graphtriyne.
Molecules
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College of Science, Liaoning Petrochemical University, Fushun 113001, China.
The electronic structure characteristics of bilayer graphyne, bilayer graphdiyne, and bilayer graphtriyne were systematically studied using molecular orbital (MO) analysis, density of states (DOS), and interaction region indicator (IRI) methods. The delocalization characteristics of the out-of-plane and in-plane π electrons (i.e.
View Article and Find Full Text PDFThe Role of Polarizability in Isoelectronic Ions: The Case of Pseudohalides.
Molecules
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Department of Chemistry "Ugo Schiff" and CSGI, University of Florence, 50019 Sesto Fiorentino, Italy.
Specific ion effects are widespread and have been studied for over a century, yet they remain poorly understood. Terms like "kosmotropes" and "chaotropes" are convenient rules of thumb but the frequent reversal of the Hofmeister series implies their limitations. Polarizability is often used to classify ions, with kosmotropes considered low in polarizability and chaotropes high.
View Article and Find Full Text PDFA multiscale functional map of somatic mutations in cancer integrating protein structure and network topology.
Nat Commun
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Department of Computational Biology, Cornell University, Ithaca, 14853, NY, USA.
A major goal of cancer biology is to understand the mechanisms driven by somatically acquired mutations. Two distinct methodologies-one analyzing mutation clustering within protein sequences and 3D structures, the other leveraging protein-protein interaction network topology-offer complementary strengths. We present NetFlow3D, a unified, end-to-end 3D structurally-informed protein interaction network propagation framework that maps the multiscale mechanistic effects of mutations.
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