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Interplay between BMI, neutrophil, triglyceride and uric acid: a case-control study and bidirectional multivariate mendelian randomization analysis.
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School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, Hubei, 430065, China.
Background: This study aims to explore the interplay between body mass index (BMI), neutrophils, triglyceride levels, and uric acid (UA). Understanding the causal correlation between UA and health indicators, specifically its association with the body's inflammatory conditions, is crucial for preventing and managing various diseases.
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January 2025
Life and Environmental Science College, Wenzhou University, 325003, Wenzhou, China; Zhejiang Provincial Key Laboratory for Subtropical Water Environment and Marine Biological Resources Protection, Wenzhou University, 325003, Wenzhou, China. Electronic address:
The nitrate pollution has become an increasingly serious environmental problem worldwide, and the toxic effects of elevated nitrate levels in the environment on aquatic animals remain to be elucidated. The purpose of the present study was to investigate the mechanisms of liver injury to tadpoles after exposure to nitrate from embryonic to metamorphic climax and to assess the recovery process of liver function after cessation of exposure. In the group with continuous nitrate exposure, the livers and thyroid of tadpoles showed remarkably histological lesions, of this with structural disorganization of the hepatocytes, cellular atrophy, and fibrosis, as well as significant reduction in the follicular and colloidal area of the thyroid.
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Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, International Innovation Center for Forest Chemicals and Materials, College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037 China. Electronic address:
The mechanical flexibility and high conductivity of hydrogel electrolytes are crucial for their application in supercapacitors. In this study, we developed hydrogel electrolyte based on lignocellulose nanofibers (LCNFs) through nanofibrillation and self-catalytic gelation in a glycerinum/choline chloride/aluminum chloride hexahydrate (Gly/ChCl/AlCl·6HO) metal-based neutral deep eutectic solvent (DES) system. The lignin-Al self-catalytic mechanism offered an eco-friendly and sustainable method for synthesizing hydrogel electrolytes, while enhancing their ionic conductivity.
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Institute of Environmental Science and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, 030006, China. Electronic address:
Lipid droplets (LDs) are essential organelles used to store lipids and participate in cellular lipid metabolism. Imaging LDs is an intuitive approach to comprehend their biological functions. Herein, the LDs-targeted CDs (LD-CDs) featuring robust solvatochromic emission were elaborately designed by a Schiff base reaction using 1, 2-diamino-4-fluorobenzene, 3-dimethylaminophenol, and thiourea as precursors.
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School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. Electronic address:
Hepatocellular carcinoma (HCC) stands as a grave illness characterized by elevated death rates. Early identification plays a vital role in improving patient survival. Herein, a novel split-type dual-mode biosensor featuring with near-infrared photoelectronchemical (PEC) and colorimetric sensing characteristics was developed for the high-performance detection of HepG2 cells.
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