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Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias.
J Cardiovasc Dev Dis
December 2024
Department of Cardiology, Rush University Medical Center, Chicago, IL 60612, USA.
Pulsed field ablation (PFA) is a catheter-based procedure that utilizes short high voltage and short-duration electrical field pulses to induce tissue injury. The last decade has yielded significant scientific progress and quickened interest in PFA as an energy modality leading to the emergence of the clinical use of PFA technologies for the treatment of atrial fibrillation. It is generally agreed that more research is needed to improve our biophysical understanding of PFA for clinical cardiac applications as well as its potential as a potential alternative energy source to thermal ablation modalities for the treatment of other arrhythmias.
View Article and Find Full Text PDFGated myocardial perfusion SPECT for evaluating left ventricular dyssynchrony in cardiac resynchronization therapy candidates: a systematic review.
Nucl Med Commun
January 2025
Department of Cardiac and Vascular Diseases, St.John Paul II Hospital, Jagiellonian University Medical College, Krakow, Poland.
Objectives: Cardiac resynchronization therapy (CRT) is an intervention for heart failure patients with reduced ejection fraction who exhibit specific electrocardiographic indicators of electrical dyssynchrony. However, electrical dyssynchrony does not universally correspond to left ventricular mechanical dyssynchrony (LVMD). Gated single-photon emission computed tomography (SPECT) myocardial perfusion allows for the assessment of LVMD, yet its role in the CRT selection process remains debated.
View Article and Find Full Text PDFMagmatic evolution of the Kikai caldera revealed by zircon triple dating and its chemistry.
Sci Rep
January 2025
Central Research Institute of Electric Power Industry, Chiba, 270-1194, Japan.
Reconstructing the volcanic history of the Kikai caldera, a large active volcano that produced a ~ 160 km eruption at 7.3 ka off the southern coast of Kyushu Island (southwest Japan), is crucial to assess potential future volcanic hazards at both regional and global scales. However, revealing its volcanic history before the 7.
View Article and Find Full Text PDFcellular model systems provide a promising alternative to animal experiments for studying the intestine-organ axis.
Crit Rev Biotechnol
January 2025
Arterra Biosciences.P.A, Naples, Italy.
Limiting animal experiments is essential for ethical issues and also because scientific evidence highlights the discrepancies between human and animal metabolism. This review aims to provide a critical discussion of the strengths and limitations of the most appropriate intestine model to answer complex research questions in pharmaceutical and nutraceutical fields. This review describes the components contributing to the definition of the gut barrier structure, from the outer mucus layer to the inner part of lamina propria, including endothelial and neuronal networks.
View Article and Find Full Text PDFNote of concern regarding the sources of scientific evidence used to justify the Reclassification of Non-Invasive Brain Stimulation (NIBS) Devices without an intended medical purpose into Class III.
Brain Stimul
January 2025
Faculty of Medicine and Health Sciences, Department of Head and Skin, Ghent Experimental Psychiatry (GHEP) lab, Ghent University, Ghent, Belgium; Neuroprotection and Neuromodulation Research Group (NEUR), Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium; Department of Psychiatry, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium; Center for Care and Cure Technology (C3Te), Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
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